STRINGSTRING
recR recR Tola_2216 Tola_2216 recO recO dnaX dnaX recF recF dnaA dnaA Tola_3141 Tola_3141 xerC xerC Tola_1996 Tola_1996 htpG htpG Tola_0349 Tola_0349
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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recRRecombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (200 aa)    
Predicted Functional Partners:
Tola_2216
Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
 
  
 0.976
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
 
 
 0.949
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
  
 0.844
recF
DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.
 
  
 0.793
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
 
  
 0.725
Tola_3141
KEGG: aha:AHA_4270 chromosome partitioning protein ParB; TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; Belongs to the ParB family.
  
     0.630
xerC
Tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
  
   
 0.619
Tola_1996
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: aha:AHA_1497 pyruvate:ferredoxin (flavodoxin) oxidoreductase.
   
 
 0.617
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
   
 
 0.617
Tola_0349
TIGRFAM: DNA helicase II; PFAM: UvrD/REP helicase; KEGG: aha:AHA_0220 DNA helicase II.
 
   
 0.610
Your Current Organism:
Tolumonas auensis
NCBI taxonomy Id: 595494
Other names: T. auensis DSM 9187, Tolumonas auensis DSM 9187, Tolumonas auensis TA 4, Tolumonas auensis str. DSM 9187, Tolumonas auensis strain DSM 9187
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