node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Tola_1217 | mnmA | Tola_1217 | Tola_2325 | Sulfur relay protein, TusE/DsrC/DsvC family; Part of a sulfur-relay system. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.938 |
Tola_2327 | hflD | Tola_2327 | Tola_2326 | TIGRFAM: adenylosuccinate lyase; PFAM: Adenylosuccinate lyase domain protein; fumarate lyase; KEGG: asa:ASA_1389 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | PFAM: protein of unknown function DUF489; KEGG: asa:ASA_1390 hypothetical protein. | 0.768 |
Tola_2327 | mnmA | Tola_2327 | Tola_2325 | TIGRFAM: adenylosuccinate lyase; PFAM: Adenylosuccinate lyase domain protein; fumarate lyase; KEGG: asa:ASA_1389 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.801 |
Tola_2327 | nudJ | Tola_2327 | Tola_2324 | TIGRFAM: adenylosuccinate lyase; PFAM: Adenylosuccinate lyase domain protein; fumarate lyase; KEGG: asa:ASA_1389 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | PFAM: NUDIX hydrolase; KEGG: aha:AHA_1416 7,8-dihydro-8-oxoguanine-triphosphatase; Belongs to the Nudix hydrolase family. NudJ subfamily. | 0.564 |
Tola_2525 | Tola_2955 | Tola_2525 | Tola_2955 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: aha:AHA_0681 riboflavin biosynthesis protein RibF; Belongs to the ribF family. | 0.708 |
Tola_2525 | mnmA | Tola_2525 | Tola_2325 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.581 |
Tola_2525 | mnmE | Tola_2525 | Tola_3166 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.429 |
Tola_2955 | Tola_2525 | Tola_2955 | Tola_2525 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: aha:AHA_0681 riboflavin biosynthesis protein RibF; Belongs to the ribF family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.708 |
Tola_2955 | mnmA | Tola_2955 | Tola_2325 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: aha:AHA_0681 riboflavin biosynthesis protein RibF; Belongs to the ribF family. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.685 |
hflD | Tola_2327 | Tola_2326 | Tola_2327 | PFAM: protein of unknown function DUF489; KEGG: asa:ASA_1390 hypothetical protein. | TIGRFAM: adenylosuccinate lyase; PFAM: Adenylosuccinate lyase domain protein; fumarate lyase; KEGG: asa:ASA_1389 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.768 |
hflD | mnmA | Tola_2326 | Tola_2325 | PFAM: protein of unknown function DUF489; KEGG: asa:ASA_1390 hypothetical protein. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.942 |
hflD | nudJ | Tola_2326 | Tola_2324 | PFAM: protein of unknown function DUF489; KEGG: asa:ASA_1390 hypothetical protein. | PFAM: NUDIX hydrolase; KEGG: aha:AHA_1416 7,8-dihydro-8-oxoguanine-triphosphatase; Belongs to the Nudix hydrolase family. NudJ subfamily. | 0.641 |
mnmA | Tola_1217 | Tola_2325 | Tola_1217 | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | Sulfur relay protein, TusE/DsrC/DsvC family; Part of a sulfur-relay system. | 0.938 |
mnmA | Tola_2327 | Tola_2325 | Tola_2327 | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | TIGRFAM: adenylosuccinate lyase; PFAM: Adenylosuccinate lyase domain protein; fumarate lyase; KEGG: asa:ASA_1389 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.801 |
mnmA | Tola_2525 | Tola_2325 | Tola_2525 | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.581 |
mnmA | Tola_2955 | Tola_2325 | Tola_2955 | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: aha:AHA_0681 riboflavin biosynthesis protein RibF; Belongs to the ribF family. | 0.685 |
mnmA | hflD | Tola_2325 | Tola_2326 | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | PFAM: protein of unknown function DUF489; KEGG: asa:ASA_1390 hypothetical protein. | 0.942 |
mnmA | mnmE | Tola_2325 | Tola_3166 | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.705 |
mnmA | mnmG | Tola_2325 | Tola_3144 | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.665 |
mnmA | nudJ | Tola_2325 | Tola_2324 | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | PFAM: NUDIX hydrolase; KEGG: aha:AHA_1416 7,8-dihydro-8-oxoguanine-triphosphatase; Belongs to the Nudix hydrolase family. NudJ subfamily. | 0.646 |