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kduI kduI Tola_3049 Tola_3049 Tola_1315 Tola_1315 uxuA uxuA parC parC Tola_0224 Tola_0224 minE minE uxaC-2 uxaC-2 Tola_3026 Tola_3026 uxaC uxaC Tola_3027 Tola_3027
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
kduI4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family. (278 aa)    
Predicted Functional Partners:
Tola_3049
TIGRFAM: 2-deoxy-D-gluconate 3-dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; KEGG: esa:ESA_00452 2-deoxy-D-gluconate 3-dehydrogenase.
 
 
 0.988
Tola_1315
PFAM: YaeQ family protein; KEGG: esa:ESA_03147 hypothetical protein.
   
    0.731
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family.
 
  
 0.696
parC
DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
    0.694
Tola_0224
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: ect:ECIAI39_4739 5-keto-D-gluconate-5-reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
  
 0.662
minE
Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
   
    0.632
uxaC-2
PFAM: Glucuronate isomerase; KEGG: kpe:KPK_0591 glucuronate isomerase.
 
  
 0.628
Tola_3026
PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: ypp:YPDSF_0367 altronate oxidoreductase.
 
   
 0.625
uxaC
PFAM: Glucuronate isomerase; KEGG: vvu:VV2_1070 glucuronate isomerase.
 
  
 0.618
Tola_3027
PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; SAF domain protein; KEGG: eca:ECA0647 altronate hydrolase.
 
  
 0.577
Your Current Organism:
Tolumonas auensis
NCBI taxonomy Id: 595494
Other names: T. auensis DSM 9187, Tolumonas auensis DSM 9187, Tolumonas auensis TA 4, Tolumonas auensis str. DSM 9187, Tolumonas auensis strain DSM 9187
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