STRINGSTRING
tiaS tiaS TSIB_1196 TSIB_1196 TSIB_1085 TSIB_1085 ribK ribK TSIB_0883 TSIB_0883 TSIB_0028 TSIB_0028 TSIB_1082 TSIB_1082 pfdB pfdB TSIB_1842 TSIB_1842 TSIB_0731 TSIB_0731 TSIB_0275 TSIB_0275
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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tiaSPutative transcription-associated protein TFIIS; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. (429 aa)    
Predicted Functional Partners:
TSIB_1196
Putative HTH-type transcriptional regulatory protein TK0539.
 
     0.712
TSIB_1085
Hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family.
  
     0.681
ribK
Riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
  
     0.670
TSIB_0883
GHMP kinase.
 
     0.620
TSIB_0028
Ribosomal protein S24E; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
 
     0.613
TSIB_1082
Nicotinamide-nucleotide adenylyltransferase.
  
     0.586
pfdB
Prefoldin subunit beta; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
  
     0.561
TSIB_1842
Sun/NOL1/NOP nucleolar protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
      
 0.532
TSIB_0731
Hypothetical protein.
 
     0.527
TSIB_0275
Transcription regulator, SpoVT/AbrB family, containing PhoU domain.
  
     0.499
Your Current Organism:
Thermococcus sibiricus
NCBI taxonomy Id: 604354
Other names: T. sibiricus MM 739, Thermococcus sibiricus MM 739, Thermococcus sibiricus str. MM 739, Thermococcus sibiricus strain MM 739
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