STRINGSTRING
LOC103247786 LOC103247786 EZH2 EZH2 LOC103221971 LOC103221971 LOC103247785 LOC103247785 HAT1 HAT1 SUZ12 SUZ12 JARID2 JARID2 EED EED CARM1 CARM1 AEBP2 AEBP2 CBX1 CBX1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurrence
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[Homology]
Score
LOC103247786Histone H3; Belongs to the histone H3 family. (136 aa)    
Predicted Functional Partners:
EZH2
Enhancer of zeste 2 polycomb repressive complex 2 subunit.
   
 0.992
LOC103221971
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.986
LOC103247785
Histone H2A; Belongs to the histone H2A family.
 
 
 0.985
HAT1
Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG.
   
 0.964
SUZ12
SUZ12 polycomb repressive complex 2 subunit.
    
 0.944
JARID2
Jumonji and AT-rich interaction domain containing 2.
   
 0.928
EED
Embryonic ectoderm development.
   
 0.924
CARM1
Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
   
 0.913
AEBP2
AE binding protein 2.
   
 0.906
CBX1
Chromobox 1.
   
 0.902
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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