node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FtsL | hemY | azo0877 | azo0996 | Putative cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | HemY protein. involved in a late step of protoheme ix synthesis; High confidence in function and specificity. | 0.424 |
FtsL | lolB | azo0877 | azo0757 | Putative cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Conserved hypothetical outer membrane lipoprotein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | 0.639 |
FtsL | nudJ | azo0877 | azo2774 | Putative cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Conserved hypothetical protein; Putative Nudix hydrolase ymfB (EC 3.6.-.-). mutt: mutator mutT protein; Specificity unclear; Belongs to the Nudix hydrolase family. NudJ subfamily. | 0.499 |
FtsL | omlA | azo0877 | azo2577 | Putative cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Putative outer membrane lipoprotein OmlA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.590 |
azo0758 | ispE | azo0758 | azo0756 | Conserved hypothetical secreted protein. Homology to cv4061 of C. violaceum of 37% (trembl|Q7NQS6). InterPro: TPR repeat (IPR001440) signal peptide no TMHs; Conserved hypothetical protein. | Probable 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.800 |
azo0758 | lolB | azo0758 | azo0757 | Conserved hypothetical secreted protein. Homology to cv4061 of C. violaceum of 37% (trembl|Q7NQS6). InterPro: TPR repeat (IPR001440) signal peptide no TMHs; Conserved hypothetical protein. | Conserved hypothetical outer membrane lipoprotein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | 0.847 |
azo0758 | mutM | azo0758 | azo0759 | Conserved hypothetical secreted protein. Homology to cv4061 of C. violaceum of 37% (trembl|Q7NQS6). InterPro: TPR repeat (IPR001440) signal peptide no TMHs; Conserved hypothetical protein. | MutM protein; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.577 |
hemY | FtsL | azo0996 | azo0877 | HemY protein. involved in a late step of protoheme ix synthesis; High confidence in function and specificity. | Putative cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.424 |
hemY | lolB | azo0996 | azo0757 | HemY protein. involved in a late step of protoheme ix synthesis; High confidence in function and specificity. | Conserved hypothetical outer membrane lipoprotein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | 0.672 |
ispE | azo0758 | azo0756 | azo0758 | Probable 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | Conserved hypothetical secreted protein. Homology to cv4061 of C. violaceum of 37% (trembl|Q7NQS6). InterPro: TPR repeat (IPR001440) signal peptide no TMHs; Conserved hypothetical protein. | 0.800 |
ispE | lolB | azo0756 | azo0757 | Probable 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | Conserved hypothetical outer membrane lipoprotein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | 0.864 |
ispE | mutM | azo0756 | azo0759 | Probable 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | MutM protein; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.578 |
lepB | lolB | azo1640 | azo0757 | LepB protein; Signal peptidase I (EC 3.4.21.89) (SPase I) (Leader peptidase I). SPase I is an integral membrane protein that is anchored in the cytoplasmic membrane by one or two N-terminal transmembrane domains, with the main part of the protein protuding in the periplasmic space. SPase I can cleave N-terminal leader sequences of nonlipoprotein that are exported by the SecYEG pathway or the twin arginine translocation (Tat) pathway. Pfam: Peptidase_S26 probable 2 TMH no signal peptide; High confidence in function and specificity. | Conserved hypothetical outer membrane lipoprotein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | 0.581 |
lepB | minE | azo1640 | azo1654 | LepB protein; Signal peptidase I (EC 3.4.21.89) (SPase I) (Leader peptidase I). SPase I is an integral membrane protein that is anchored in the cytoplasmic membrane by one or two N-terminal transmembrane domains, with the main part of the protein protuding in the periplasmic space. SPase I can cleave N-terminal leader sequences of nonlipoprotein that are exported by the SecYEG pathway or the twin arginine translocation (Tat) pathway. Pfam: Peptidase_S26 probable 2 TMH no signal peptide; High confidence in function and specificity. | Putative cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.700 |
lolA | lolB | azo1366 | azo0757 | Putative outer membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | Conserved hypothetical outer membrane lipoprotein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | 0.695 |
lolA | omlA | azo1366 | azo2577 | Putative outer membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | Putative outer membrane lipoprotein OmlA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.611 |
lolB | FtsL | azo0757 | azo0877 | Conserved hypothetical outer membrane lipoprotein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | Putative cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.639 |
lolB | azo0758 | azo0757 | azo0758 | Conserved hypothetical outer membrane lipoprotein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | Conserved hypothetical secreted protein. Homology to cv4061 of C. violaceum of 37% (trembl|Q7NQS6). InterPro: TPR repeat (IPR001440) signal peptide no TMHs; Conserved hypothetical protein. | 0.847 |
lolB | hemY | azo0757 | azo0996 | Conserved hypothetical outer membrane lipoprotein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | HemY protein. involved in a late step of protoheme ix synthesis; High confidence in function and specificity. | 0.672 |
lolB | ispE | azo0757 | azo0756 | Conserved hypothetical outer membrane lipoprotein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | Probable 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.864 |