node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
azo0793 | azo0794 | azo0793 | azo0794 | Probable phosphatase (HAD superfamily); Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate TREMBL:Q9JSU3: 43% identity, 59% similarity InterPro: IPR006549; HAD-SF-IIIA. IPR005834; Hydrolase. IPR008230; Sugar_Ptase. IPR010023; YrbI_phosphatas. Pfam: PF00702; Hydrolase TIGR00099: conserved hypothetical prote Absence of transmembrane helices; Specificity unclear. | Arabinose 5-phosphate isomerase (EC 5.3.1.13). Catalyzes the interconversion of D-arabinose 5-phosphate and D-ribulose 5-phosphate (By similarity). InterPro: KpsF/GutQ family protein kpsF: KpsF/GutQ family protein; High confidence in function and specificity; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.998 |
azo0793 | kdsA | azo0793 | azo2145 | Probable phosphatase (HAD superfamily); Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate TREMBL:Q9JSU3: 43% identity, 59% similarity InterPro: IPR006549; HAD-SF-IIIA. IPR005834; Hydrolase. IPR008230; Sugar_Ptase. IPR010023; YrbI_phosphatas. Pfam: PF00702; Hydrolase TIGR00099: conserved hypothetical prote Absence of transmembrane helices; Specificity unclear. | 2-dehydro-3-deoxyphosphooctonate aldolase (EC 2.5.1.55) (Phospho-2- dehydro-3-deoxyoctonate aldolase) (3-deoxy-D-manno-octulosonic acid 8- phosphate synthetase) (KDO-8-phosphate synthetase) (KDO 8-P synthase) (KDOPS). Homology to kdsA of Pseudomonas aeruginosa of 45% (gi|6647573|sp|Q9ZFK4|KDSA_PSEAE(SwissProt (ExPASy))). Tigrfam: 3-deoxy-8-phosphooctulonate synthase. This HMM describes 3-deoxy-8-phosphooctulonate synthase. Alternate names include 2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-d-manno-octulosonic acid 8-phosphate and KDO-8 phosphate synthetase. It catalyzes the aldo [...] | 0.985 |
azo0793 | kdsB | azo0793 | azo1472 | Probable phosphatase (HAD superfamily); Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate TREMBL:Q9JSU3: 43% identity, 59% similarity InterPro: IPR006549; HAD-SF-IIIA. IPR005834; Hydrolase. IPR008230; Sugar_Ptase. IPR010023; YrbI_phosphatas. Pfam: PF00702; Hydrolase TIGR00099: conserved hypothetical prote Absence of transmembrane helices; Specificity unclear. | Probable 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.981 |
azo0793 | lpxB | azo0793 | azo1896 | Probable phosphatase (HAD superfamily); Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate TREMBL:Q9JSU3: 43% identity, 59% similarity InterPro: IPR006549; HAD-SF-IIIA. IPR005834; Hydrolase. IPR008230; Sugar_Ptase. IPR010023; YrbI_phosphatas. Pfam: PF00702; Hydrolase TIGR00099: conserved hypothetical prote Absence of transmembrane helices; Specificity unclear. | Probable lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.654 |
azo0793 | lpxC | azo0793 | azo0890 | Probable phosphatase (HAD superfamily); Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate TREMBL:Q9JSU3: 43% identity, 59% similarity InterPro: IPR006549; HAD-SF-IIIA. IPR005834; Hydrolase. IPR008230; Sugar_Ptase. IPR010023; YrbI_phosphatas. Pfam: PF00702; Hydrolase TIGR00099: conserved hypothetical prote Absence of transmembrane helices; Specificity unclear. | Probable UDP-3-O-acyl N-acetylglycosmaine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.690 |
azo0793 | lpxD | azo0793 | azo1899 | Probable phosphatase (HAD superfamily); Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate TREMBL:Q9JSU3: 43% identity, 59% similarity InterPro: IPR006549; HAD-SF-IIIA. IPR005834; Hydrolase. IPR008230; Sugar_Ptase. IPR010023; YrbI_phosphatas. Pfam: PF00702; Hydrolase TIGR00099: conserved hypothetical prote Absence of transmembrane helices; Specificity unclear. | Probable UDP-3-O-[3-hydroxymyristol] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.653 |
azo0793 | lpxK | azo0793 | azo1470 | Probable phosphatase (HAD superfamily); Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate TREMBL:Q9JSU3: 43% identity, 59% similarity InterPro: IPR006549; HAD-SF-IIIA. IPR005834; Hydrolase. IPR008230; Sugar_Ptase. IPR010023; YrbI_phosphatas. Pfam: PF00702; Hydrolase TIGR00099: conserved hypothetical prote Absence of transmembrane helices; Specificity unclear. | Probable tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.606 |
azo0793 | waaA | azo0793 | azo0851 | Probable phosphatase (HAD superfamily); Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate TREMBL:Q9JSU3: 43% identity, 59% similarity InterPro: IPR006549; HAD-SF-IIIA. IPR005834; Hydrolase. IPR008230; Sugar_Ptase. IPR010023; YrbI_phosphatas. Pfam: PF00702; Hydrolase TIGR00099: conserved hypothetical prote Absence of transmembrane helices; Specificity unclear. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.720 |
azo0794 | azo0793 | azo0794 | azo0793 | Arabinose 5-phosphate isomerase (EC 5.3.1.13). Catalyzes the interconversion of D-arabinose 5-phosphate and D-ribulose 5-phosphate (By similarity). InterPro: KpsF/GutQ family protein kpsF: KpsF/GutQ family protein; High confidence in function and specificity; Belongs to the SIS family. GutQ/KpsF subfamily. | Probable phosphatase (HAD superfamily); Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate TREMBL:Q9JSU3: 43% identity, 59% similarity InterPro: IPR006549; HAD-SF-IIIA. IPR005834; Hydrolase. IPR008230; Sugar_Ptase. IPR010023; YrbI_phosphatas. Pfam: PF00702; Hydrolase TIGR00099: conserved hypothetical prote Absence of transmembrane helices; Specificity unclear. | 0.998 |
azo0794 | kdsA | azo0794 | azo2145 | Arabinose 5-phosphate isomerase (EC 5.3.1.13). Catalyzes the interconversion of D-arabinose 5-phosphate and D-ribulose 5-phosphate (By similarity). InterPro: KpsF/GutQ family protein kpsF: KpsF/GutQ family protein; High confidence in function and specificity; Belongs to the SIS family. GutQ/KpsF subfamily. | 2-dehydro-3-deoxyphosphooctonate aldolase (EC 2.5.1.55) (Phospho-2- dehydro-3-deoxyoctonate aldolase) (3-deoxy-D-manno-octulosonic acid 8- phosphate synthetase) (KDO-8-phosphate synthetase) (KDO 8-P synthase) (KDOPS). Homology to kdsA of Pseudomonas aeruginosa of 45% (gi|6647573|sp|Q9ZFK4|KDSA_PSEAE(SwissProt (ExPASy))). Tigrfam: 3-deoxy-8-phosphooctulonate synthase. This HMM describes 3-deoxy-8-phosphooctulonate synthase. Alternate names include 2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-d-manno-octulosonic acid 8-phosphate and KDO-8 phosphate synthetase. It catalyzes the aldo [...] | 0.992 |
azo0794 | kdsB | azo0794 | azo1472 | Arabinose 5-phosphate isomerase (EC 5.3.1.13). Catalyzes the interconversion of D-arabinose 5-phosphate and D-ribulose 5-phosphate (By similarity). InterPro: KpsF/GutQ family protein kpsF: KpsF/GutQ family protein; High confidence in function and specificity; Belongs to the SIS family. GutQ/KpsF subfamily. | Probable 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.891 |
azo0794 | lpxB | azo0794 | azo1896 | Arabinose 5-phosphate isomerase (EC 5.3.1.13). Catalyzes the interconversion of D-arabinose 5-phosphate and D-ribulose 5-phosphate (By similarity). InterPro: KpsF/GutQ family protein kpsF: KpsF/GutQ family protein; High confidence in function and specificity; Belongs to the SIS family. GutQ/KpsF subfamily. | Probable lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.878 |
azo0794 | lpxC | azo0794 | azo0890 | Arabinose 5-phosphate isomerase (EC 5.3.1.13). Catalyzes the interconversion of D-arabinose 5-phosphate and D-ribulose 5-phosphate (By similarity). InterPro: KpsF/GutQ family protein kpsF: KpsF/GutQ family protein; High confidence in function and specificity; Belongs to the SIS family. GutQ/KpsF subfamily. | Probable UDP-3-O-acyl N-acetylglycosmaine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.882 |
azo0794 | lpxD | azo0794 | azo1899 | Arabinose 5-phosphate isomerase (EC 5.3.1.13). Catalyzes the interconversion of D-arabinose 5-phosphate and D-ribulose 5-phosphate (By similarity). InterPro: KpsF/GutQ family protein kpsF: KpsF/GutQ family protein; High confidence in function and specificity; Belongs to the SIS family. GutQ/KpsF subfamily. | Probable UDP-3-O-[3-hydroxymyristol] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.881 |
azo0794 | lpxK | azo0794 | azo1470 | Arabinose 5-phosphate isomerase (EC 5.3.1.13). Catalyzes the interconversion of D-arabinose 5-phosphate and D-ribulose 5-phosphate (By similarity). InterPro: KpsF/GutQ family protein kpsF: KpsF/GutQ family protein; High confidence in function and specificity; Belongs to the SIS family. GutQ/KpsF subfamily. | Probable tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.887 |
azo0794 | waaA | azo0794 | azo0851 | Arabinose 5-phosphate isomerase (EC 5.3.1.13). Catalyzes the interconversion of D-arabinose 5-phosphate and D-ribulose 5-phosphate (By similarity). InterPro: KpsF/GutQ family protein kpsF: KpsF/GutQ family protein; High confidence in function and specificity; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.885 |
exbB3 | kdsB | azo1468 | azo1472 | Conserved hypothetical biopolymer transport protein ExbB. Homology to exbB of B. pertussis. ExbB is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. Pfam: MotA/TolQ/ExbB proton channel family no signal peptide probable 3 TMHS; Family membership. | Probable 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.871 |
exbB3 | lpxB | azo1468 | azo1896 | Conserved hypothetical biopolymer transport protein ExbB. Homology to exbB of B. pertussis. ExbB is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. Pfam: MotA/TolQ/ExbB proton channel family no signal peptide probable 3 TMHS; Family membership. | Probable lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.447 |
exbB3 | lpxD | azo1468 | azo1899 | Conserved hypothetical biopolymer transport protein ExbB. Homology to exbB of B. pertussis. ExbB is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. Pfam: MotA/TolQ/ExbB proton channel family no signal peptide probable 3 TMHS; Family membership. | Probable UDP-3-O-[3-hydroxymyristol] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.471 |
exbB3 | lpxK | azo1468 | azo1470 | Conserved hypothetical biopolymer transport protein ExbB. Homology to exbB of B. pertussis. ExbB is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. Pfam: MotA/TolQ/ExbB proton channel family no signal peptide probable 3 TMHS; Family membership. | Probable tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.860 |