STRINGSTRING
mshA mshA mshB mshB mshD mshD mshC mshC ACR18640.1 ACR18640.1 mca mca ACR17236.1 ACR17236.1 fadD3 fadD3 gpmA gpmA ACR16861.1 ACR16861.1 glgB glgB
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
mshAMshA glycosyltransferase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway. (451 aa)    
Predicted Functional Partners:
mshB
MshB deacetylase; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
 
  
 0.945
mshD
MshD acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
  
   
 0.938
mshC
MshC ligase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
  
   
 0.875
ACR18640.1
Hypothetical protein.
 
     0.864
mca
Mycothiol conjugate amidase; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily.
 
  
 0.818
ACR17236.1
Glutaredoxin and related proteins.
  
   
 0.708
fadD3
acyl-CoA synthetase.
       0.687
gpmA
Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
       0.681
ACR16861.1
Putative sugar transferase.
 
  
 0.663
glgB
1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
   
 0.627
Your Current Organism:
Corynebacterium kroppenstedtii
NCBI taxonomy Id: 645127
Other names: C. kroppenstedtii DSM 44385, Corynebacterium kroppenstedtii CCUG 35717, Corynebacterium kroppenstedtii CIP 105744, Corynebacterium kroppenstedtii DSM 44385, Corynebacterium kroppenstedtii str. DSM 44385, Corynebacterium kroppenstedtii strain DSM 44385
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