node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
TK1334 | TK1697 | TK1334 | TK1697 | dephospho-CoA kinase; Belongs to the UPF0200 family. | Hypothetical protein, conserved, DUF359 family; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). Can also use UTP, with lower efficiency and has weak activity with ATP, but shows a strong preference for GTP as the phosphate donor. | 0.826 |
TK1334 | coaBC | TK1334 | TK0517 | dephospho-CoA kinase; Belongs to the UPF0200 family. | Phosphopantothenoylcysteine synthetase/decarboxylase; Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'- phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'- phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.783 |
TK1334 | coaD | TK1334 | TK2128 | dephospho-CoA kinase; Belongs to the UPF0200 family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. | 0.743 |
TK1697 | TK1334 | TK1697 | TK1334 | Hypothetical protein, conserved, DUF359 family; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). Can also use UTP, with lower efficiency and has weak activity with ATP, but shows a strong preference for GTP as the phosphate donor. | dephospho-CoA kinase; Belongs to the UPF0200 family. | 0.826 |
TK1697 | TK1699 | TK1697 | TK1699 | Hypothetical protein, conserved, DUF359 family; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). Can also use UTP, with lower efficiency and has weak activity with ATP, but shows a strong preference for GTP as the phosphate donor. | DNA-directed RNA polymerase, subunit E'. | 0.937 |
TK1697 | TK2192 | TK1697 | TK2192 | Hypothetical protein, conserved, DUF359 family; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). Can also use UTP, with lower efficiency and has weak activity with ATP, but shows a strong preference for GTP as the phosphate donor. | dephospho-CoA kinase. | 0.976 |
TK1697 | coaBC | TK1697 | TK0517 | Hypothetical protein, conserved, DUF359 family; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). Can also use UTP, with lower efficiency and has weak activity with ATP, but shows a strong preference for GTP as the phosphate donor. | Phosphopantothenoylcysteine synthetase/decarboxylase; Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'- phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'- phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.644 |
TK1697 | coaD | TK1697 | TK2128 | Hypothetical protein, conserved, DUF359 family; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). Can also use UTP, with lower efficiency and has weak activity with ATP, but shows a strong preference for GTP as the phosphate donor. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. | 0.978 |
TK1697 | ppa | TK1697 | TK1700 | Hypothetical protein, conserved, DUF359 family; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). Can also use UTP, with lower efficiency and has weak activity with ATP, but shows a strong preference for GTP as the phosphate donor. | Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. | 0.739 |
TK1697 | rps24e | TK1697 | TK1696 | Hypothetical protein, conserved, DUF359 family; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). Can also use UTP, with lower efficiency and has weak activity with ATP, but shows a strong preference for GTP as the phosphate donor. | SSU ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family. | 0.982 |
TK1697 | rps27ae | TK1697 | TK1695 | Hypothetical protein, conserved, DUF359 family; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). Can also use UTP, with lower efficiency and has weak activity with ATP, but shows a strong preference for GTP as the phosphate donor. | SSU ribosomal protein S27AE; Belongs to the eukaryotic ribosomal protein eS31 family. | 0.942 |
TK1697 | rps6e | TK1697 | TK1951 | Hypothetical protein, conserved, DUF359 family; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). Can also use UTP, with lower efficiency and has weak activity with ATP, but shows a strong preference for GTP as the phosphate donor. | SSU ribosomal protein S6E; Belongs to the eukaryotic ribosomal protein eS6 family. | 0.740 |
TK1697 | spt4 | TK1697 | TK1698 | Hypothetical protein, conserved, DUF359 family; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). Can also use UTP, with lower efficiency and has weak activity with ATP, but shows a strong preference for GTP as the phosphate donor. | DNA-directed RNA polymerase subunit E'; Stimulates transcription elongation; Belongs to the archaeal Spt4 family. | 0.864 |
TK1699 | TK1697 | TK1699 | TK1697 | DNA-directed RNA polymerase, subunit E'. | Hypothetical protein, conserved, DUF359 family; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). Can also use UTP, with lower efficiency and has weak activity with ATP, but shows a strong preference for GTP as the phosphate donor. | 0.937 |
TK1699 | ppa | TK1699 | TK1700 | DNA-directed RNA polymerase, subunit E'. | Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. | 0.739 |
TK1699 | rps24e | TK1699 | TK1696 | DNA-directed RNA polymerase, subunit E'. | SSU ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family. | 0.935 |
TK1699 | rps27ae | TK1699 | TK1695 | DNA-directed RNA polymerase, subunit E'. | SSU ribosomal protein S27AE; Belongs to the eukaryotic ribosomal protein eS31 family. | 0.930 |
TK1699 | rps6e | TK1699 | TK1951 | DNA-directed RNA polymerase, subunit E'. | SSU ribosomal protein S6E; Belongs to the eukaryotic ribosomal protein eS6 family. | 0.632 |
TK1699 | spt4 | TK1699 | TK1698 | DNA-directed RNA polymerase, subunit E'. | DNA-directed RNA polymerase subunit E'; Stimulates transcription elongation; Belongs to the archaeal Spt4 family. | 0.993 |
TK2192 | TK1697 | TK2192 | TK1697 | dephospho-CoA kinase. | Hypothetical protein, conserved, DUF359 family; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). Can also use UTP, with lower efficiency and has weak activity with ATP, but shows a strong preference for GTP as the phosphate donor. | 0.976 |