node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HI_1333 | ftsH | HI_1333 | HI_1335 | Conserved hypothetical protein; Similar to SP:P42550 PID:606118 GB:U00096 PID:1789570 percent identity: 75.00; identified by sequence similarity; putative. | Cell division protein (ftsH); Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | 0.403 |
HI_1333 | rlmE | HI_1333 | HI_1334 | Conserved hypothetical protein; Similar to SP:P42550 PID:606118 GB:U00096 PID:1789570 percent identity: 75.00; identified by sequence similarity; putative. | Cell division protein (ftsJ); Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.581 |
HI_1333 | rpsP | HI_1333 | HI_0204 | Conserved hypothetical protein; Similar to SP:P42550 PID:606118 GB:U00096 PID:1789570 percent identity: 75.00; identified by sequence similarity; putative. | Ribosomal protein S16 (rpS16); Similar to SP:P02372 PID:43143 GB:U00096 PID:1788961 percent identity: 70.73; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bS16 family. | 0.587 |
HI_1333 | rsfS | HI_1333 | HI_0034 | Conserved hypothetical protein; Similar to SP:P42550 PID:606118 GB:U00096 PID:1789570 percent identity: 75.00; identified by sequence similarity; putative. | Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.467 |
HI_1333 | topA | HI_1333 | HI_1365 | Conserved hypothetical protein; Similar to SP:P42550 PID:606118 GB:U00096 PID:1789570 percent identity: 75.00; identified by sequence similarity; putative. | DNA topoisomerase I (topA); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing D [...] | 0.420 |
ftsH | HI_1333 | HI_1335 | HI_1333 | Cell division protein (ftsH); Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | Conserved hypothetical protein; Similar to SP:P42550 PID:606118 GB:U00096 PID:1789570 percent identity: 75.00; identified by sequence similarity; putative. | 0.403 |
ftsH | rlmE | HI_1335 | HI_1334 | Cell division protein (ftsH); Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | Cell division protein (ftsJ); Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.773 |
ftsH | rpsP | HI_1335 | HI_0204 | Cell division protein (ftsH); Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | Ribosomal protein S16 (rpS16); Similar to SP:P02372 PID:43143 GB:U00096 PID:1788961 percent identity: 70.73; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bS16 family. | 0.689 |
rlmE | HI_1333 | HI_1334 | HI_1333 | Cell division protein (ftsJ); Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | Conserved hypothetical protein; Similar to SP:P42550 PID:606118 GB:U00096 PID:1789570 percent identity: 75.00; identified by sequence similarity; putative. | 0.581 |
rlmE | ftsH | HI_1334 | HI_1335 | Cell division protein (ftsJ); Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | Cell division protein (ftsH); Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | 0.773 |
rlmE | rsfS | HI_1334 | HI_0034 | Cell division protein (ftsJ); Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.497 |
rpsP | HI_1333 | HI_0204 | HI_1333 | Ribosomal protein S16 (rpS16); Similar to SP:P02372 PID:43143 GB:U00096 PID:1788961 percent identity: 70.73; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bS16 family. | Conserved hypothetical protein; Similar to SP:P42550 PID:606118 GB:U00096 PID:1789570 percent identity: 75.00; identified by sequence similarity; putative. | 0.587 |
rpsP | ftsH | HI_0204 | HI_1335 | Ribosomal protein S16 (rpS16); Similar to SP:P02372 PID:43143 GB:U00096 PID:1788961 percent identity: 70.73; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bS16 family. | Cell division protein (ftsH); Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | 0.689 |
rsfS | HI_1333 | HI_0034 | HI_1333 | Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | Conserved hypothetical protein; Similar to SP:P42550 PID:606118 GB:U00096 PID:1789570 percent identity: 75.00; identified by sequence similarity; putative. | 0.467 |
rsfS | rlmE | HI_0034 | HI_1334 | Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | Cell division protein (ftsJ); Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.497 |
topA | HI_1333 | HI_1365 | HI_1333 | DNA topoisomerase I (topA); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing D [...] | Conserved hypothetical protein; Similar to SP:P42550 PID:606118 GB:U00096 PID:1789570 percent identity: 75.00; identified by sequence similarity; putative. | 0.420 |