node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG34224 | gcm | FBpp0111332 | FBpp0307464 | HDC05732; DNA-binding transcription factor activity. It is involved in the biological process described with: regulation of transcription, DNA-templated. | Glial cells missing (gcm) encodes an essential zinc finger transcription factor that determines the fate of the lateral glial cells. It is involved in the differentiation of plasmatocytes, tendon cells and specific neurons. | 0.519 |
GATAe | gcm | FBpp0082672 | FBpp0307464 | Transcription factor dGATAe; GATAe (GATAe) encodes a endoderm-specific GATA factor. It regulates endoderm differentiation and intestinal stem cell maintenance. | Glial cells missing (gcm) encodes an essential zinc finger transcription factor that determines the fate of the lateral glial cells. It is involved in the differentiation of plasmatocytes, tendon cells and specific neurons. | 0.709 |
GATAe | hkb | FBpp0082672 | FBpp0078591 | Transcription factor dGATAe; GATAe (GATAe) encodes a endoderm-specific GATA factor. It regulates endoderm differentiation and intestinal stem cell maintenance. | Huckebein (hkb) is expressed in patches within the embryonic neuroectoderm and a subset of neuroblasts and their progeny, where it is required for proper neuronal specification and axon targeting. It is a terminal gap gene mediating the maternal terminal information at the posterior end of the blastoderm embryo. | 0.478 |
GATAe | nej | FBpp0082672 | FBpp0291862 | Transcription factor dGATAe; GATAe (GATAe) encodes a endoderm-specific GATA factor. It regulates endoderm differentiation and intestinal stem cell maintenance. | Nejire, isoform C; Nejire (nej) encodes the transcriptional co-activator CBP. It acetylates several nuclear proteins, including the histone encoded by His3 on K18, K27, and H4 on K8. By regulating gene expression, the product of nej has roles in cell proliferation, cell signaling and differentiation, and in developmental patterning. | 0.630 |
gcm | CG34224 | FBpp0307464 | FBpp0111332 | Glial cells missing (gcm) encodes an essential zinc finger transcription factor that determines the fate of the lateral glial cells. It is involved in the differentiation of plasmatocytes, tendon cells and specific neurons. | HDC05732; DNA-binding transcription factor activity. It is involved in the biological process described with: regulation of transcription, DNA-templated. | 0.519 |
gcm | GATAe | FBpp0307464 | FBpp0082672 | Glial cells missing (gcm) encodes an essential zinc finger transcription factor that determines the fate of the lateral glial cells. It is involved in the differentiation of plasmatocytes, tendon cells and specific neurons. | Transcription factor dGATAe; GATAe (GATAe) encodes a endoderm-specific GATA factor. It regulates endoderm differentiation and intestinal stem cell maintenance. | 0.709 |
gcm | hkb | FBpp0307464 | FBpp0078591 | Glial cells missing (gcm) encodes an essential zinc finger transcription factor that determines the fate of the lateral glial cells. It is involved in the differentiation of plasmatocytes, tendon cells and specific neurons. | Huckebein (hkb) is expressed in patches within the embryonic neuroectoderm and a subset of neuroblasts and their progeny, where it is required for proper neuronal specification and axon targeting. It is a terminal gap gene mediating the maternal terminal information at the posterior end of the blastoderm embryo. | 0.585 |
gcm | nej | FBpp0307464 | FBpp0291862 | Glial cells missing (gcm) encodes an essential zinc finger transcription factor that determines the fate of the lateral glial cells. It is involved in the differentiation of plasmatocytes, tendon cells and specific neurons. | Nejire, isoform C; Nejire (nej) encodes the transcriptional co-activator CBP. It acetylates several nuclear proteins, including the histone encoded by His3 on K18, K27, and H4 on K8. By regulating gene expression, the product of nej has roles in cell proliferation, cell signaling and differentiation, and in developmental patterning. | 0.508 |
gcm | nerfin-1 | FBpp0307464 | FBpp0072489 | Glial cells missing (gcm) encodes an essential zinc finger transcription factor that determines the fate of the lateral glial cells. It is involved in the differentiation of plasmatocytes, tendon cells and specific neurons. | Nervous fingers 1 (nerfin-1) encodes a zinc finger transcription factor that regulates early axon guidance at the embryonic stage and is required for the maintenance of larval neuron differentiation. In the larval medulla cortex, nerfin-1 is expressed in medulla neurons at the early stage and protects them from dedifferentiation via the repression of Notch signaling pathway. | 0.587 |
gcm | repo | FBpp0307464 | FBpp0082986 | Glial cells missing (gcm) encodes an essential zinc finger transcription factor that determines the fate of the lateral glial cells. It is involved in the differentiation of plasmatocytes, tendon cells and specific neurons. | Reversed polarity (repo) encodes a homeodomain transcription factor specifically expressed in glial cells. It is is a direct target of the pan-glial fate determinant encoded by gcm and is required for acquisition of glial fate and subsequent terminal glial differentiation. | 0.933 |
gcm | slmb | FBpp0307464 | FBpp0303082 | Glial cells missing (gcm) encodes an essential zinc finger transcription factor that determines the fate of the lateral glial cells. It is involved in the differentiation of plasmatocytes, tendon cells and specific neurons. | Supernumerary limbs (slmb) encodes an essential, conserved F-box protein and a component of the SCF (Skp/Cullin/F-box) E3 ubiquitin-ligase, providing substrate specificity to the SCF. It negatively regulates multiple signaling pathways and cellular processes by promoting the proteasome-mediated degradation or cleavage of its targets, including the products of arm and ci (Wg and Hh signaling), SAK, per and Cap-H2. | 0.510 |
gcm | sna | FBpp0307464 | FBpp0080298 | Glial cells missing (gcm) encodes an essential zinc finger transcription factor that determines the fate of the lateral glial cells. It is involved in the differentiation of plasmatocytes, tendon cells and specific neurons. | Snail (sna) encodes a transcription factor that contributes to embryonic mesoderm development, epithelial to mesenchymal transition and asymmetric cell division. | 0.601 |
gcm | ttk | FBpp0307464 | FBpp0085186 | Glial cells missing (gcm) encodes an essential zinc finger transcription factor that determines the fate of the lateral glial cells. It is involved in the differentiation of plasmatocytes, tendon cells and specific neurons. | Protein tramtrack, alpha isoform; Binds to a number of sites in the transcriptional regulatory region of ftz. Isoform alpha is required to repress genes that promote the R7 cell fate. Probable repressor of the transcription of the segmentation genes ftz, eve, h, odd, run, and en. May bind to the region 5'-AGGG[CT]GG-3'. Degradation of ttk is directed by binding of sinah or sina, via the adapter molecule phyl which binds to the BTB domain of ttk. | 0.545 |
gcm | wor | FBpp0307464 | FBpp0080299 | Glial cells missing (gcm) encodes an essential zinc finger transcription factor that determines the fate of the lateral glial cells. It is involved in the differentiation of plasmatocytes, tendon cells and specific neurons. | Worniu (wor) encodes a zinc finger C2H2 transcription factor involved in nervous system development. It contributes to neuroblast asymmetric cell division and brain development. | 0.518 |
hkb | GATAe | FBpp0078591 | FBpp0082672 | Huckebein (hkb) is expressed in patches within the embryonic neuroectoderm and a subset of neuroblasts and their progeny, where it is required for proper neuronal specification and axon targeting. It is a terminal gap gene mediating the maternal terminal information at the posterior end of the blastoderm embryo. | Transcription factor dGATAe; GATAe (GATAe) encodes a endoderm-specific GATA factor. It regulates endoderm differentiation and intestinal stem cell maintenance. | 0.478 |
hkb | gcm | FBpp0078591 | FBpp0307464 | Huckebein (hkb) is expressed in patches within the embryonic neuroectoderm and a subset of neuroblasts and their progeny, where it is required for proper neuronal specification and axon targeting. It is a terminal gap gene mediating the maternal terminal information at the posterior end of the blastoderm embryo. | Glial cells missing (gcm) encodes an essential zinc finger transcription factor that determines the fate of the lateral glial cells. It is involved in the differentiation of plasmatocytes, tendon cells and specific neurons. | 0.585 |
hkb | sna | FBpp0078591 | FBpp0080298 | Huckebein (hkb) is expressed in patches within the embryonic neuroectoderm and a subset of neuroblasts and their progeny, where it is required for proper neuronal specification and axon targeting. It is a terminal gap gene mediating the maternal terminal information at the posterior end of the blastoderm embryo. | Snail (sna) encodes a transcription factor that contributes to embryonic mesoderm development, epithelial to mesenchymal transition and asymmetric cell division. | 0.510 |
nej | GATAe | FBpp0291862 | FBpp0082672 | Nejire, isoform C; Nejire (nej) encodes the transcriptional co-activator CBP. It acetylates several nuclear proteins, including the histone encoded by His3 on K18, K27, and H4 on K8. By regulating gene expression, the product of nej has roles in cell proliferation, cell signaling and differentiation, and in developmental patterning. | Transcription factor dGATAe; GATAe (GATAe) encodes a endoderm-specific GATA factor. It regulates endoderm differentiation and intestinal stem cell maintenance. | 0.630 |
nej | gcm | FBpp0291862 | FBpp0307464 | Nejire, isoform C; Nejire (nej) encodes the transcriptional co-activator CBP. It acetylates several nuclear proteins, including the histone encoded by His3 on K18, K27, and H4 on K8. By regulating gene expression, the product of nej has roles in cell proliferation, cell signaling and differentiation, and in developmental patterning. | Glial cells missing (gcm) encodes an essential zinc finger transcription factor that determines the fate of the lateral glial cells. It is involved in the differentiation of plasmatocytes, tendon cells and specific neurons. | 0.508 |
nej | slmb | FBpp0291862 | FBpp0303082 | Nejire, isoform C; Nejire (nej) encodes the transcriptional co-activator CBP. It acetylates several nuclear proteins, including the histone encoded by His3 on K18, K27, and H4 on K8. By regulating gene expression, the product of nej has roles in cell proliferation, cell signaling and differentiation, and in developmental patterning. | Supernumerary limbs (slmb) encodes an essential, conserved F-box protein and a component of the SCF (Skp/Cullin/F-box) E3 ubiquitin-ligase, providing substrate specificity to the SCF. It negatively regulates multiple signaling pathways and cellular processes by promoting the proteasome-mediated degradation or cleavage of its targets, including the products of arm and ci (Wg and Hh signaling), SAK, per and Cap-H2. | 0.490 |