STRINGSTRING
Naa80 Naa80 Naa40 Naa40 Naa20B Naa20B Naa20A Naa20A chic chic Naa60 Naa60 Ate1 Ate1 prel prel Naa30B Naa30B anchor anchor CG13630 CG13630
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Naa80N-alpha-acetyltransferase 80; N-alpha-acetyltransferase that acetylates the amino terminal acidic residue of proteins devoid of initiator methionine. Preferentially acts on proteins starting with Asp- Asp-Asp and Glu-Glu-Glu sequences. In vitro, shows high activity towards N-terminal sequences starting with Met-Asp-Glu- Leu, Met-Glu-Glu-Glu and Met-Asp-Asp-Asp. (178 aa)    
Predicted Functional Partners:
Naa40
N(Alpha)-acetyltransferase 40; peptide-serine-N-acetyltransferase activity; H4 histone acetyltransferase activity; peptide alpha-N-acetyltransferase activity; H2A histone acetyltransferase activity. It is involved in the biological process described with: regulation of ribosomal DNA heterochromatin assembly; N-terminal protein amino acid acetylation.
      
 0.855
Naa20B
N(Alpha)-acetyltransferase 20 B, isoform A; Peptide alpha-N-acetyltransferase activity. It is involved in the biological process described with: N-terminal peptidyl-methionine acetylation.
      
 0.841
Naa20A
N(Alpha)-acetyltransferase 20 A, isoform B; Peptide alpha-N-acetyltransferase activity. It is involved in the biological process described with: negative regulation of neuron apoptotic process; histone acetylation; N-terminal peptidyl-methionine acetylation.
      
 0.840
chic
Profilin; Chickadee (chic) encodes an actin monomer binding protein that provides the major cellular pool of readily polymerizing ATP-actin monomers. It is involved in oogenesis, spermatogenesis, cell division, bristle formation, cellular morphogenesis, axon growth, filopodia formation, dorsal closure, wound healing and stem cell maintenance.
    
 
 0.767
Naa60
N-alpha-acetyltransferase 60; Displays alpha (N-terminal) acetyltransferase activity towards a range of N-terminal sequences including those starting with Met-Lys, Met-Val, Met-Ala and Met-Met. Required for normal chromosomal segregation during anaphase. [Isoform B]: Does not show histone acetyltransferase activity toward free histones; Belongs to the acetyltransferase family. NAA60 subfamily.
   
  
 0.759
Ate1
Arginyl-tRNA--protein transferase 1; Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Does not arginylate cysteine residues (By similarity).
   
  
 0.672
prel
Preli-like (prel) encodes a mitochondrial protein in the PRELI/MSF1 family that contributes to the integrity of mitochondrial structures and the activity of respiratory chain complex IV.
   
    0.641
Naa30B
N(Alpha)-acetyltransferase 30 B; Peptide alpha-N-acetyltransferase activity. It is involved in the biological process described with: N-terminal peptidyl-methionine acetylation.
      
 0.561
anchor
Anchor, isoform B; It is involved in the biological process described with: transmembrane transport; intracellular signal transduction.
      
 0.549
CG13630
Methionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
      
 0.516
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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