STRINGSTRING
Cyp6a9 Cyp6a9 Cpr Cpr Cyp303a1 Cyp303a1 Cyp6a21 Cyp6a21 CG34458 CG34458 Lcp3 Lcp3 CG3652 CG3652 CG13667 CG13667 CG4960 CG4960 Gpo2 Gpo2 spok spok
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cyp6a9Cytochrome P450 6a9; Involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. (504 aa)    
Predicted Functional Partners:
Cpr
NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome p450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome b5 (By similarity). May function to clear the olfactory organ (antennae) from accumulating chemicals. In the N-terminal section; belongs to the flavodoxin family.
 
 
 
 0.832
Cyp303a1
Probable cytochrome P450 303a1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
  
 
 0.661
Cyp6a21
Probable cytochrome P450 6a21; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
  
 
0.610
CG34458
Peptidase S1 domain-containing protein; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
    
 
 0.605
Lcp3
Larval cuticle protein 3; Component of the larval cuticle.
    
 
 0.533
CG3652
Protein YIPF.
      
 0.523
CG13667
NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of the anamorsin/DRE2 homolog. Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family. In the N-terminal section; belongs to the flavodoxin family.
 
  
 
 0.498
CG4960
Receptor expression-enhancing protein; It is involved in the biological process described with: endoplasmic reticulum tubular network organization; regulation of intracellular transport.
    
 
 0.495
Gpo2
Glycerol-3-phosphate dehydrogenase (quinone) activity; calcium ion binding. It is involved in the biological process described with: glycerol metabolic process; glycerol-3-phosphate metabolic process; oxidation-reduction process; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
      
 0.493
spok
Spookier (spok) encodes a cytochrome P450 involved in ecdysteroid biosynthesis that is expressed primarily in the prothoracic gland and is localized in the endoplasmic reticulum. Genetic evidence suggests that the product of spok acts with the products of sro and Cyp6t3 to catalyze conversion of 7 dehydrocholesterol to delta4, diketol during the ecdysone biosynthetic pathway.
  
 
 0.491
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (22%) [HD]