STRINGSTRING
stard3 stard3 top1mt-2 top1mt-2 mospd2 mospd2 stard3nl stard3nl vapb vapb pctp pctp stard7 stard7 star star cert1a cert1a zfyve27 zfyve27 abraa abraa
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
stard3StAR-related lipid transfer protein 3; Sterol-binding protein that mediates cholesterol transport from the endoplasmic reticulum to endosomes. Creates contact site between the endoplasmic reticulum and late endosomes: localizes to late endosome membranes and contacts the endoplasmic reticulum. Acts as a lipid transfer protein that redirects sterol to the endosome at the expense of the cell membrane and favors membrane formation inside endosomes. (448 aa)    
Predicted Functional Partners:
top1mt-2
DNA topoisomerase I mitochondrial.
    
 
 0.945
mospd2
Motile sperm domain-containing 2.
   
 
 0.938
stard3nl
STARD3 N-terminal-like.
  
 
0.933
vapb
VAMP (vesicle-associated membrane protein)-associated protein B and C.
    
 
 0.908
pctp
Phosphatidylcholine transfer protein.
      
 0.847
stard7
StAR-related lipid transfer (START) domain-containing 7.
      
 0.837
star
Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone (By similarity).
     
0.815
cert1a
Ceramide transfer protein; Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner (By similarity). Isoform 1 plays a role in neural development and skeletal muscle development. Negatively regulates apoptosis during development.
   
  
 0.796
zfyve27
Zinc finger, FYVE domain-containing 27.
   
  
 0.730
abraa
Actin-binding Rho-activating protein a.
      
 0.723
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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