node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C13H9orf72 | FIG4 | ENSDARP00000005597 | ENSDARP00000152617 | Zgc:100846. | FIG4 phosphoinositide 5-phosphatase. | 0.605 |
C13H9orf72 | als2a | ENSDARP00000005597 | ENSDARP00000097741 | Zgc:100846. | Alsin Rho guanine nucleotide exchange factor ALS2 a. | 0.834 |
C13H9orf72 | chmp2ba | ENSDARP00000005597 | ENSDARP00000055865 | Zgc:100846. | Charged multivesicular body protein 2Ba. | 0.888 |
C13H9orf72 | chmp2bb | ENSDARP00000005597 | ENSDARP00000008354 | Zgc:100846. | Charged multivesicular body protein 2b; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids (By similarity). | 0.888 |
C13H9orf72 | tbk1 | ENSDARP00000005597 | ENSDARP00000132718 | Zgc:100846. | TANK-binding kinase 1. | 0.866 |
C13H9orf72 | vcp | ENSDARP00000005597 | ENSDARP00000012048 | Zgc:100846. | Transitional endoplasmic reticulum ATPase; Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles which derive from part-rough, part-smooth transitional elements of the endoplasmic reticulum (tER). Vesicle budding from the tER is an ATP-dependent process. Also involved in DNA damage response: recruited to double-strand [...] | 0.953 |
FIG4 | C13H9orf72 | ENSDARP00000152617 | ENSDARP00000005597 | FIG4 phosphoinositide 5-phosphatase. | Zgc:100846. | 0.605 |
FIG4 | als2a | ENSDARP00000152617 | ENSDARP00000097741 | FIG4 phosphoinositide 5-phosphatase. | Alsin Rho guanine nucleotide exchange factor ALS2 a. | 0.853 |
FIG4 | chmp2ba | ENSDARP00000152617 | ENSDARP00000055865 | FIG4 phosphoinositide 5-phosphatase. | Charged multivesicular body protein 2Ba. | 0.855 |
FIG4 | chmp2bb | ENSDARP00000152617 | ENSDARP00000008354 | FIG4 phosphoinositide 5-phosphatase. | Charged multivesicular body protein 2b; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids (By similarity). | 0.855 |
FIG4 | tbk1 | ENSDARP00000152617 | ENSDARP00000132718 | FIG4 phosphoinositide 5-phosphatase. | TANK-binding kinase 1. | 0.597 |
FIG4 | vcp | ENSDARP00000152617 | ENSDARP00000012048 | FIG4 phosphoinositide 5-phosphatase. | Transitional endoplasmic reticulum ATPase; Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles which derive from part-rough, part-smooth transitional elements of the endoplasmic reticulum (tER). Vesicle budding from the tER is an ATP-dependent process. Also involved in DNA damage response: recruited to double-strand [...] | 0.758 |
als2a | C13H9orf72 | ENSDARP00000097741 | ENSDARP00000005597 | Alsin Rho guanine nucleotide exchange factor ALS2 a. | Zgc:100846. | 0.834 |
als2a | FIG4 | ENSDARP00000097741 | ENSDARP00000152617 | Alsin Rho guanine nucleotide exchange factor ALS2 a. | FIG4 phosphoinositide 5-phosphatase. | 0.853 |
als2a | chmp2ba | ENSDARP00000097741 | ENSDARP00000055865 | Alsin Rho guanine nucleotide exchange factor ALS2 a. | Charged multivesicular body protein 2Ba. | 0.874 |
als2a | chmp2bb | ENSDARP00000097741 | ENSDARP00000008354 | Alsin Rho guanine nucleotide exchange factor ALS2 a. | Charged multivesicular body protein 2b; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids (By similarity). | 0.874 |
als2a | tbk1 | ENSDARP00000097741 | ENSDARP00000132718 | Alsin Rho guanine nucleotide exchange factor ALS2 a. | TANK-binding kinase 1. | 0.595 |
als2a | vcp | ENSDARP00000097741 | ENSDARP00000012048 | Alsin Rho guanine nucleotide exchange factor ALS2 a. | Transitional endoplasmic reticulum ATPase; Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles which derive from part-rough, part-smooth transitional elements of the endoplasmic reticulum (tER). Vesicle budding from the tER is an ATP-dependent process. Also involved in DNA damage response: recruited to double-strand [...] | 0.760 |
chmp1a | chmp1b | ENSDARP00000141533 | ENSDARP00000134015 | Charged multivesicular body protein 1a; Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids (By similarity). Belongs to the SNF7 family. | Charged multivesicular body protein 1b; Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. | 0.905 |
chmp1a | chmp2a | ENSDARP00000141533 | ENSDARP00000070582 | Charged multivesicular body protein 1a; Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids (By similarity). Belongs to the SNF7 family. | Charged multivesicular body protein 2a; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids (By similarity). | 0.996 |