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bcs1l bcs1l uqcrq uqcrq lyrm7 lyrm7 uqcrfs1 uqcrfs1 slc39a7 slc39a7 mrpl16 mrpl16 cox10 cox10 taco1 taco1 LOC100534805 LOC100534805 cox15 cox15 twnk twnk
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
bcs1lMitochondrial chaperone BCS1; Chaperone necessary for the assembly of mitochondrial respiratory chain complex III; Belongs to the AAA ATPase family. BCS1 subfamily. (420 aa)    
Predicted Functional Partners:
uqcrq
Ubiquinol-cytochrome c reductase, complex III subunit VII.
   
 
 0.875
lyrm7
Complex III assembly factor LYRM7; Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane (By similarity).
    
 
 0.851
uqcrfs1
Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
  
 
 0.829
slc39a7
Zinc transporter Slc39a7; Zinc transporter, that transports Zn(2+) from the endoplasmic reticulum/Golgi apparatus to the cytosol; Belongs to the ZIP transporter (TC 2.A.5) family. KE4/Catsup subfamily.
 
 
    0.807
mrpl16
Mitochondrial ribosomal protein L16; Belongs to the universal ribosomal protein uL16 family.
   
 
 0.797
cox10
Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family.
   
  
 0.787
taco1
Translational activator of mitochondrially encoded cytochrome c oxidase I.
  
  
 0.786
LOC100534805
Translational activator of mitochondrially encoded cytochrome c oxidase I.
  
  
 0.783
cox15
Cytochrome c oxidase assembly homolog 15 (yeast).
   
  
 0.772
twnk
Twinkle mtDNA helicase.
      
 0.742
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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