node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SH3RF3 | zfyve28 | ENSDARP00000131264 | ENSDARP00000116818 | Si:ch211-124n19.2. | Lateral signaling target protein 2 homolog; Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated (By similarity); Belongs to the lst-2 family. | 0.574 |
col5a3a | zfyve28 | ENSDARP00000141009 | ENSDARP00000116818 | Collagen, type V, alpha 3a. | Lateral signaling target protein 2 homolog; Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated (By similarity); Belongs to the lst-2 family. | 0.480 |
eps8l3b | jph1a | ENSDARP00000114441 | ENSDARP00000144362 | EPS8-like 3b. | Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. | 0.511 |
eps8l3b | pik3r3b | ENSDARP00000114441 | ENSDARP00000040333 | EPS8-like 3b. | Phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (P55, gamma). | 0.410 |
eps8l3b | ush1c | ENSDARP00000114441 | ENSDARP00000104974 | EPS8-like 3b. | Usher syndrome 1C (Autosomal recessive, severe). | 0.546 |
eps8l3b | zfyve28 | ENSDARP00000114441 | ENSDARP00000116818 | EPS8-like 3b. | Lateral signaling target protein 2 homolog; Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated (By similarity); Belongs to the lst-2 family. | 0.837 |
exd3 | zfyve28 | ENSDARP00000086444 | ENSDARP00000116818 | Exonuclease 3'-5' domain-containing 3. | Lateral signaling target protein 2 homolog; Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated (By similarity); Belongs to the lst-2 family. | 0.592 |
il6r | zfyve28 | ENSDARP00000154692 | ENSDARP00000116818 | Interleukin 6 receptor. | Lateral signaling target protein 2 homolog; Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated (By similarity); Belongs to the lst-2 family. | 0.479 |
jph1a | eps8l3b | ENSDARP00000144362 | ENSDARP00000114441 | Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. | EPS8-like 3b. | 0.511 |
jph1a | zfyve28 | ENSDARP00000144362 | ENSDARP00000116818 | Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. | Lateral signaling target protein 2 homolog; Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated (By similarity); Belongs to the lst-2 family. | 0.721 |
pik3r3b | eps8l3b | ENSDARP00000040333 | ENSDARP00000114441 | Phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (P55, gamma). | EPS8-like 3b. | 0.410 |
pik3r3b | zfyve28 | ENSDARP00000040333 | ENSDARP00000116818 | Phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (P55, gamma). | Lateral signaling target protein 2 homolog; Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated (By similarity); Belongs to the lst-2 family. | 0.644 |
sdf4 | zfyve28 | ENSDARP00000094806 | ENSDARP00000116818 | 45 kDa calcium-binding protein; May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment; Belongs to the CREC family. | Lateral signaling target protein 2 homolog; Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated (By similarity); Belongs to the lst-2 family. | 0.485 |
si:dkey-97o5.1 | zfyve28 | ENSDARP00000061728 | ENSDARP00000116818 | Uncharacterized protein C1orf112 homolog. | Lateral signaling target protein 2 homolog; Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated (By similarity); Belongs to the lst-2 family. | 0.557 |
ush1c | eps8l3b | ENSDARP00000104974 | ENSDARP00000114441 | Usher syndrome 1C (Autosomal recessive, severe). | EPS8-like 3b. | 0.546 |
ush1c | zfyve28 | ENSDARP00000104974 | ENSDARP00000116818 | Usher syndrome 1C (Autosomal recessive, severe). | Lateral signaling target protein 2 homolog; Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated (By similarity); Belongs to the lst-2 family. | 0.542 |
zfyve28 | SH3RF3 | ENSDARP00000116818 | ENSDARP00000131264 | Lateral signaling target protein 2 homolog; Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated (By similarity); Belongs to the lst-2 family. | Si:ch211-124n19.2. | 0.574 |
zfyve28 | col5a3a | ENSDARP00000116818 | ENSDARP00000141009 | Lateral signaling target protein 2 homolog; Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated (By similarity); Belongs to the lst-2 family. | Collagen, type V, alpha 3a. | 0.480 |
zfyve28 | eps8l3b | ENSDARP00000116818 | ENSDARP00000114441 | Lateral signaling target protein 2 homolog; Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated (By similarity); Belongs to the lst-2 family. | EPS8-like 3b. | 0.837 |
zfyve28 | exd3 | ENSDARP00000116818 | ENSDARP00000086444 | Lateral signaling target protein 2 homolog; Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated (By similarity); Belongs to the lst-2 family. | Exonuclease 3'-5' domain-containing 3. | 0.592 |