node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Hnf4b | vdrb | ENSDARP00000149108 | ENSDARP00000125655 | NR LBD domain-containing protein. | Vitamin D3 receptor B; Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells. Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR. The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3- responsive target genes. Recruited to promoters via its interaction with BAZ1B/WSTF which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis. | 0.753 |
acp5b | vdrb | ENSDARP00000141681 | ENSDARP00000125655 | Tartrate-resistant acid phosphatase type 5. | Vitamin D3 receptor B; Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells. Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR. The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3- responsive target genes. Recruited to promoters via its interaction with BAZ1B/WSTF which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis. | 0.666 |
cyp24a1 | cyp27b1 | ENSDARP00000130345 | ENSDARP00000142417 | Cytochrome P450, family 24, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. | Cytochrome P450, family 27, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. | 0.926 |
cyp24a1 | cyp2r1 | ENSDARP00000130345 | ENSDARP00000073546 | Cytochrome P450, family 24, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. | Cytochrome P450, family 2, subfamily R, polypeptide 1; Belongs to the cytochrome P450 family. | 0.950 |
cyp24a1 | slc8a1b | ENSDARP00000130345 | ENSDARP00000109925 | Cytochrome P450, family 24, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. | Solute carrier family 8 member 1b; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. | 0.541 |
cyp24a1 | trpv6 | ENSDARP00000130345 | ENSDARP00000105890 | Cytochrome P450, family 24, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. | Transient receptor potential cation channel, subfamily V, member 6; Belongs to the transient receptor (TC 1.A.4) family. | 0.578 |
cyp24a1 | vdrb | ENSDARP00000130345 | ENSDARP00000125655 | Cytochrome P450, family 24, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. | Vitamin D3 receptor B; Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells. Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR. The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3- responsive target genes. Recruited to promoters via its interaction with BAZ1B/WSTF which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis. | 0.705 |
cyp27a1.2 | cyp2r1 | ENSDARP00000118414 | ENSDARP00000073546 | Cytochrome P450, family 27, subfamily A, polypeptide 1, gene 2; Belongs to the cytochrome P450 family. | Cytochrome P450, family 2, subfamily R, polypeptide 1; Belongs to the cytochrome P450 family. | 0.482 |
cyp27a1.2 | vdrb | ENSDARP00000118414 | ENSDARP00000125655 | Cytochrome P450, family 27, subfamily A, polypeptide 1, gene 2; Belongs to the cytochrome P450 family. | Vitamin D3 receptor B; Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells. Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR. The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3- responsive target genes. Recruited to promoters via its interaction with BAZ1B/WSTF which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis. | 0.609 |
cyp27b1 | cyp24a1 | ENSDARP00000142417 | ENSDARP00000130345 | Cytochrome P450, family 27, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. | Cytochrome P450, family 24, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. | 0.926 |
cyp27b1 | cyp2r1 | ENSDARP00000142417 | ENSDARP00000073546 | Cytochrome P450, family 27, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. | Cytochrome P450, family 2, subfamily R, polypeptide 1; Belongs to the cytochrome P450 family. | 0.961 |
cyp27b1 | slc8a1b | ENSDARP00000142417 | ENSDARP00000109925 | Cytochrome P450, family 27, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. | Solute carrier family 8 member 1b; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. | 0.742 |
cyp27b1 | trpv6 | ENSDARP00000142417 | ENSDARP00000105890 | Cytochrome P450, family 27, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. | Transient receptor potential cation channel, subfamily V, member 6; Belongs to the transient receptor (TC 1.A.4) family. | 0.757 |
cyp27b1 | vdrb | ENSDARP00000142417 | ENSDARP00000125655 | Cytochrome P450, family 27, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. | Vitamin D3 receptor B; Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells. Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR. The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3- responsive target genes. Recruited to promoters via its interaction with BAZ1B/WSTF which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis. | 0.770 |
cyp2r1 | cyp24a1 | ENSDARP00000073546 | ENSDARP00000130345 | Cytochrome P450, family 2, subfamily R, polypeptide 1; Belongs to the cytochrome P450 family. | Cytochrome P450, family 24, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. | 0.950 |
cyp2r1 | cyp27a1.2 | ENSDARP00000073546 | ENSDARP00000118414 | Cytochrome P450, family 2, subfamily R, polypeptide 1; Belongs to the cytochrome P450 family. | Cytochrome P450, family 27, subfamily A, polypeptide 1, gene 2; Belongs to the cytochrome P450 family. | 0.482 |
cyp2r1 | cyp27b1 | ENSDARP00000073546 | ENSDARP00000142417 | Cytochrome P450, family 2, subfamily R, polypeptide 1; Belongs to the cytochrome P450 family. | Cytochrome P450, family 27, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. | 0.961 |
cyp2r1 | slc8a1b | ENSDARP00000073546 | ENSDARP00000109925 | Cytochrome P450, family 2, subfamily R, polypeptide 1; Belongs to the cytochrome P450 family. | Solute carrier family 8 member 1b; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. | 0.568 |
cyp2r1 | trpv6 | ENSDARP00000073546 | ENSDARP00000105890 | Cytochrome P450, family 2, subfamily R, polypeptide 1; Belongs to the cytochrome P450 family. | Transient receptor potential cation channel, subfamily V, member 6; Belongs to the transient receptor (TC 1.A.4) family. | 0.590 |
cyp2r1 | vdrb | ENSDARP00000073546 | ENSDARP00000125655 | Cytochrome P450, family 2, subfamily R, polypeptide 1; Belongs to the cytochrome P450 family. | Vitamin D3 receptor B; Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells. Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR. The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3- responsive target genes. Recruited to promoters via its interaction with BAZ1B/WSTF which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis. | 0.695 |