STRINGSTRING
pnhd pnhd nfyb nfyb nfya nfya pole3 pole3 admp admp htra1 htra1 serpine2 serpine2 grem1 grem1 admp2 admp2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pnhdSolute carrier family 2 member 2. (319 aa)    
Predicted Functional Partners:
nfyb
Cyclin-dependent kinase 5, regulatory subunit 1 (p35).
   
 
 0.682
nfya
Uncharacterized protein.
    
 
 0.675
pole3
Polymerase (DNA directed), epsilon 3 (P17 subunit).
    
 
 0.675
admp
Novel protein similar to anti-dorsalizing morphogenic protein.
  
   
 0.511
htra1
Serine protease HTRA1; Serine protease with a variety of targets, including extracellular matrix proteins and proteoglycans such as biglycan, syndecan-4 and glypican-4. Through cleavage of proteoglycans, may release soluble FGF-glycosaminoglycan complexes that promote the range and intensity of FGF signals in the extracellular space. Consequently, facilitates inductive processes in the developping embryo, such as posteriorization, mesoderm induction and neuronal differentiation. Regulates the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. Inhibits [...]
      
 0.416
serpine2
SERPIN domain-containing protein; Belongs to the serpin family.
      
 0.410
grem1
Gremlin.
      
 0.410
admp2
TGF_BETA_2 domain-containing protein.
  
   
 0.406
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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