STRINGSTRING
fadA fadA fadB fadB fadJ fadJ ABK48552.1 ABK48552.1 ABK47901.1 ABK47901.1 fadI fadI ABK48998.1 ABK48998.1 ABK48997.1 ABK48997.1 ABK49331.1 ABK49331.1 ABK47785.1 ABK47785.1 ABK47908.1 ABK47908.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fadA3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (387 aa)    
Predicted Functional Partners:
fadB
3-hydroxyacyl-CoA dehydrogenase / short chain enoyl-CoA hydratase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
 0.999
fadJ
Short chain enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
 0.999
ABK48552.1
PFAM: acyl-CoA dehydrogenase domain protein; KEGG: son:SO2536 oxidoreductase, acyl-CoA dehydrogenase family.
 
 0.965
ABK47901.1
hydroxymethylglutaryl-CoA lyase; PFAM: pyruvate carboxyltransferase; KEGG: son:SO1893 hydroxymethylglutaryl-CoA lyase.
  
 
 0.931
fadI
3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
  
  
 
0.921
ABK48998.1
TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; KEGG: son:SO1677 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
  
 
0.917
ABK48997.1
TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: son:SO1678 methylmalonate-semialdehyde dehydrogenase.
   
 0.907
ABK49331.1
TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: hch:HCH_01157 methylmalonate-semialdehyde dehydrogenase.
   
 0.905
ABK47785.1
Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
    
 0.891
ABK47908.1
PFAM: AMP-dependent synthetase and ligase; KEGG: mag:amb2304 acyl-coenzyme A synthetase/AMP-(fatty) acid ligase.
  
 
 0.878
Your Current Organism:
Shewanella sp. ANA3
NCBI taxonomy Id: 94122
Other names: S. sp. ANA-3, Shewanella sp. ANA-3, Shewanella sp. arsenana, Shewanella trabarsenatis
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.