STRINGSTRING
DOK6 DOK6 EFR3A EFR3A SEMA3E SEMA3E COL5A2 COL5A2 RET RET NLGN4X NLGN4X GDNF GDNF CRK CRK CRKL CRKL GRAP GRAP GRB2 GRB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DOK6Docking protein 6. (331 aa)    
Predicted Functional Partners:
EFR3A
EFR3A isoform 1.
   
  
 0.887
SEMA3E
SEMA3E isoform 1; Belongs to the semaphorin family.
      
 0.866
COL5A2
Collagen type V alpha 2 chain.
      
 0.860
RET
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
    
 0.661
NLGN4X
NLGN4X isoform 2.
   
  
 0.598
GDNF
GDNF isoform 6.
     
 0.559
CRK
CRK isoform 1.
    
 0.461
CRKL
CRKL isoform 1.
    
 0.461
GRAP
GRAP isoform 1.
    
 0.408
GRB2
Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family.
    
 0.408
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: low (24%) [HD]