STRINGSTRING
H1F0 H1F0 CDK2 CDK2 H2AC20 H2AC20 KPNB1 KPNB1 H2AC21 H2AC21 HIST2H2BE HIST2H2BE H2BC14 H2BC14 LOC100436122-8 LOC100436122-8 CR201_G0025626 CR201_G0025626 LOC100456589 LOC100456589 CDK1 CDK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H1F0Histone H1.0, N-terminally processed; Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The histones H1.0 are found in cells that are in terminal stages of differentiation or that have low rates of cell division (By similarity). (194 aa)    
Predicted Functional Partners:
CDK2
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
   
 0.943
H2AC20
Histone H2A; Belongs to the histone H2A family.
   
 0.887
KPNB1
KPNB1 isoform 1.
    
 
 0.883
H2AC21
Histone H2A; Belongs to the histone H2A family.
   
 0.880
HIST2H2BE
Histone H2B; Belongs to the histone H2B family.
   
 0.875
H2BC14
Histone H2B; Belongs to the histone H2B family.
   
 0.842
LOC100436122-8
Histone H3.1.
   
 0.842
CR201_G0025626
DFFB isoform 3.
    
 0.817
LOC100456589
Histone H2B; Belongs to the histone H2B family.
   
 0.803
CDK1
Cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis. Phosphorylates PARVA/actopaxin, APC, AMPH, APC, BARD1, Bcl-xL/BCL2L1, BRCA2, CALD1, CASP8, CDC7, CDC20, CDC25A, CDC25C, CC2D1A, CENPA, CSNK2 proteins/CKII, FZR1/CDH1, CDK7, CEBPB, CHAMP1, DMD/dystrophin, EEF1 proteins/EF-1, EZH2, KIF11/EG5, EGFR, FANCG, FOS, G [...]
   
 0.770
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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