STRINGSTRING
PEBP4 PEBP4 MRPL40 MRPL40 DAP3 DAP3 MRPL19 MRPL19 MRPL27 MRPL27 MRPL46 MRPL46 MRPS10 MRPS10 MAP2K1 MAP2K1 MRPS5 MRPS5 MRPS35 MRPS35 MRPL16 MRPL16
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
PEBP4Phosphatidylethanolamine-binding protein 4; Seems to promote cellular resistance to TNF-induced apoptosis by inhibiting activation of the Raf-1/MEK/ERK pathway, JNK and phosphatidylethanolamine externalization. Belongs to the phosphatidylethanolamine-binding protein family. (227 aa)    
Predicted Functional Partners:
MRPL40
Mitochondrial ribosomal protein L40; Belongs to the mitochondrion-specific ribosomal protein mL40 family.
   
 
 0.844
DAP3
28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family.
   
 
 0.826
MRPL19
Mitochondrial ribosomal protein L19.
   
 
 0.820
MRPL27
Mitochondrial ribosomal protein L27.
   
 
 0.816
MRPL46
Mitochondrial ribosomal protein L46; Belongs to the mitochondrion-specific ribosomal protein mL46 family.
   
 
 0.816
MRPS10
Mitochondrial ribosomal protein S10; Belongs to the universal ribosomal protein uS10 family.
   
 
 0.811
MAP2K1
Dual specificity mitogen-activated protein kinase kinase 1; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2. Both MAP2K1/MEK1 and MAP2K2/MEK2 function specifically in the MAPK/ERK cascade, and catalyze the concomitant phosphorylation of a threonine and a tyrosine resid [...]
    
 
 0.804
MRPS5
Mitochondrial ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.
   
   0.801
MRPS35
Mitochondrial ribosomal protein S35.
   
   0.796
MRPL16
Mitochondrial ribosomal protein L16; Belongs to the universal ribosomal protein uL16 family.
   
 
 0.795
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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