node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MRPL15 | MRPL18 | ENSP00000260102 | ENSP00000356001 | Mitochondrial ribosomal protein L15. | 39S ribosomal protein L18, mitochondrial; Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA. | 0.967 |
MRPL15 | MRPL19 | ENSP00000260102 | ENSP00000377486 | Mitochondrial ribosomal protein L15. | Mitochondrial ribosomal protein L19. | 0.983 |
MRPL15 | MRPL27 | ENSP00000260102 | ENSP00000225969 | Mitochondrial ribosomal protein L15. | Mitochondrial ribosomal protein L27. | 0.998 |
MRPL15 | MRPL3 | ENSP00000260102 | ENSP00000264995 | Mitochondrial ribosomal protein L15. | Mitochondrial ribosomal protein L3. | 0.997 |
MRPL15 | MRPL38 | ENSP00000260102 | ENSP00000308275 | Mitochondrial ribosomal protein L15. | Mitochondrial ribosomal protein L38; Belongs to the phosphatidylethanolamine-binding protein family. Mitochondrion-specific ribosomal protein mL38 subfamily. | 0.988 |
MRPL15 | MRPL4 | ENSP00000260102 | ENSP00000306902 | Mitochondrial ribosomal protein L15. | Mitochondrial ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family. | 0.999 |
MRPL15 | MRPL40 | ENSP00000260102 | ENSP00000333401 | Mitochondrial ribosomal protein L15. | Mitochondrial ribosomal protein L40; Belongs to the mitochondrion-specific ribosomal protein mL40 family. | 0.941 |
MRPL15 | MRPL41 | ENSP00000260102 | ENSP00000360498 | Mitochondrial ribosomal protein L15. | 39S ribosomal protein L41, mitochondrial; Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins. | 0.961 |
MRPL15 | MRPL44 | ENSP00000260102 | ENSP00000258383 | Mitochondrial ribosomal protein L15. | 39S ribosomal protein L44, mitochondrial; Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome. | 0.944 |
MRPL15 | MRPL47 | ENSP00000260102 | ENSP00000417602 | Mitochondrial ribosomal protein L15. | Mitochondrial ribosomal protein L47; Belongs to the universal ribosomal protein uL29 family. | 0.998 |
MRPL18 | MRPL15 | ENSP00000356001 | ENSP00000260102 | 39S ribosomal protein L18, mitochondrial; Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA. | Mitochondrial ribosomal protein L15. | 0.967 |
MRPL18 | MRPL19 | ENSP00000356001 | ENSP00000377486 | 39S ribosomal protein L18, mitochondrial; Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA. | Mitochondrial ribosomal protein L19. | 0.974 |
MRPL18 | MRPL27 | ENSP00000356001 | ENSP00000225969 | 39S ribosomal protein L18, mitochondrial; Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA. | Mitochondrial ribosomal protein L27. | 0.977 |
MRPL18 | MRPL3 | ENSP00000356001 | ENSP00000264995 | 39S ribosomal protein L18, mitochondrial; Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA. | Mitochondrial ribosomal protein L3. | 0.970 |
MRPL18 | MRPL38 | ENSP00000356001 | ENSP00000308275 | 39S ribosomal protein L18, mitochondrial; Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA. | Mitochondrial ribosomal protein L38; Belongs to the phosphatidylethanolamine-binding protein family. Mitochondrion-specific ribosomal protein mL38 subfamily. | 0.993 |
MRPL18 | MRPL4 | ENSP00000356001 | ENSP00000306902 | 39S ribosomal protein L18, mitochondrial; Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA. | Mitochondrial ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family. | 0.988 |
MRPL18 | MRPL40 | ENSP00000356001 | ENSP00000333401 | 39S ribosomal protein L18, mitochondrial; Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA. | Mitochondrial ribosomal protein L40; Belongs to the mitochondrion-specific ribosomal protein mL40 family. | 0.957 |
MRPL18 | MRPL41 | ENSP00000356001 | ENSP00000360498 | 39S ribosomal protein L18, mitochondrial; Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA. | 39S ribosomal protein L41, mitochondrial; Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins. | 0.955 |
MRPL18 | MRPL44 | ENSP00000356001 | ENSP00000258383 | 39S ribosomal protein L18, mitochondrial; Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA. | 39S ribosomal protein L44, mitochondrial; Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome. | 0.978 |
MRPL18 | MRPL47 | ENSP00000356001 | ENSP00000417602 | 39S ribosomal protein L18, mitochondrial; Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA. | Mitochondrial ribosomal protein L47; Belongs to the universal ribosomal protein uL29 family. | 0.977 |