STRINGSTRING
PGBD2 PGBD2 ZBED8 ZBED8 PGBD1 PGBD1 ZNF862 ZNF862 THAP9 THAP9 PGBD5 PGBD5 POGK POGK ERCC6 ERCC6 ZNF672 ZNF672 BET1L BET1L NAIF1 NAIF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PGBD2piggyBac transposable element derived 2. (592 aa)    
Predicted Functional Partners:
ZBED8
Protein ZBED8; Zinc finger BED-type containing 8.
  
  
 0.692
PGBD1
piggyBac transposable element derived 1.
  
 
 
0.653
ZNF862
Zinc finger protein 862; May be involved in transcriptional regulation.
  
  
 0.603
THAP9
DNA transposase THAP9; Active transposase that specifically recognizes the bipartite 5'-TXXGGGX(A/T)-3' consensus motif and mediates transposition.
   
  
 0.563
PGBD5
PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. Can induce genomic rearrangements that inactivate the HPRT1 gene.
    
 
0.542
POGK
Pogo transposable element derived with KRAB domain.
   
  
 0.530
ERCC6
DNA excision repair protein ERCC-6; Essential factor involved in transcription-coupled nucleotide excision repair which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, thereby modifying the interface between stalled RNA polymerase II and DNA. It is required for transcription-coupled repair complex formation. It recruits the CSA complex (DCX(ERCC8) complex), nucleotide excision repair proteins and EP300 to the sites of RNA polymerase II-b [...]
   
 
 0.527
ZNF672
Zinc finger protein 672; May be involved in transcriptional regulation.
   
  
 0.487
BET1L
BET1-like protein; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity).
      
 0.480
NAIF1
Nuclear apoptosis-inducing factor 1; Induces apoptosis; Belongs to the NAIF1 family.
   
  
 0.456
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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