node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABI3BP | OLFML1 | ENSP00000284322 | ENSP00000332511 | Target of Nesh-SH3; ABI family member 3 binding protein. | Olfactomedin-like protein 1; Olfactomedin like 1. | 0.406 |
ADCY4 | OLFML1 | ENSP00000312126 | ENSP00000332511 | Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Olfactomedin-like protein 1; Olfactomedin like 1. | 0.444 |
ATOH8 | OLFML1 | ENSP00000304676 | ENSP00000332511 | Protein atonal homolog 8; Transcription factor that binds a palindromic (canonical) core consensus DNA sequence 5'-CANNTG- 3' known as an E-box element, possibly as a heterodimer with other bHLH proteins. Regulates endothelial cell proliferation, migration and tube-like structures formation. Modulates endothelial cell differentiation through NOS3. May be implicated in specification and differentiation of neuronal cell lineages in the brain (By similarity). May participate in kidney development and may be involved in podocyte differentiation (By similarity). During early embryonic devel [...] | Olfactomedin-like protein 1; Olfactomedin like 1. | 0.444 |
ATOH8 | SRPX2 | ENSP00000304676 | ENSP00000362095 | Protein atonal homolog 8; Transcription factor that binds a palindromic (canonical) core consensus DNA sequence 5'-CANNTG- 3' known as an E-box element, possibly as a heterodimer with other bHLH proteins. Regulates endothelial cell proliferation, migration and tube-like structures formation. Modulates endothelial cell differentiation through NOS3. May be implicated in specification and differentiation of neuronal cell lineages in the brain (By similarity). May participate in kidney development and may be involved in podocyte differentiation (By similarity). During early embryonic devel [...] | Sushi repeat-containing protein SRPX2; Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration and adhesion. Increases the phosphorylation levels of FAK. Interacts with and increases the mitogenic activity of HGF. Promotes synapse formation. May have a role in the perisylvian region, critical for language and cognitive development. | 0.400 |
CTXN1 | OLFML1 | ENSP00000313226 | ENSP00000332511 | Cortexin-1; May mediate extracellular or intracellular signaling of cortical neurons during forebrain development; Belongs to the cortexin family. | Olfactomedin-like protein 1; Olfactomedin like 1. | 0.411 |
DCN | ECM2 | ENSP00000052754 | ENSP00000344758 | Decorin; May affect the rate of fibrils formation. | Extracellular matrix protein 2; Promotes matrix assembly and cell adhesiveness. | 0.684 |
DCN | MFAP4 | ENSP00000052754 | ENSP00000378957 | Decorin; May affect the rate of fibrils formation. | Microfibril-associated glycoprotein 4; Could be involved in calcium-dependent cell adhesion or intercellular interactions. May contribute to the elastic fiber assembly and/or maintenance. | 0.555 |
DCN | OLFML1 | ENSP00000052754 | ENSP00000332511 | Decorin; May affect the rate of fibrils formation. | Olfactomedin-like protein 1; Olfactomedin like 1. | 0.413 |
DKK2 | OLFML1 | ENSP00000285311 | ENSP00000332511 | Dickkopf-related protein 2; Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity); Belongs to the dickkopf family. | Olfactomedin-like protein 1; Olfactomedin like 1. | 0.400 |
ECM2 | DCN | ENSP00000344758 | ENSP00000052754 | Extracellular matrix protein 2; Promotes matrix assembly and cell adhesiveness. | Decorin; May affect the rate of fibrils formation. | 0.684 |
ECM2 | OLFML1 | ENSP00000344758 | ENSP00000332511 | Extracellular matrix protein 2; Promotes matrix assembly and cell adhesiveness. | Olfactomedin-like protein 1; Olfactomedin like 1. | 0.473 |
KCNE4 | OLFML1 | ENSP00000281830 | ENSP00000332511 | Potassium voltage-gated channel subfamily E member 4; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. May associate with KCNQ1/KVLTQ1 and inhibit potassium current; Belongs to the potassium channel KCNE family. | Olfactomedin-like protein 1; Olfactomedin like 1. | 0.452 |
MFAP4 | DCN | ENSP00000378957 | ENSP00000052754 | Microfibril-associated glycoprotein 4; Could be involved in calcium-dependent cell adhesion or intercellular interactions. May contribute to the elastic fiber assembly and/or maintenance. | Decorin; May affect the rate of fibrils formation. | 0.555 |
MFAP4 | OLFML1 | ENSP00000378957 | ENSP00000332511 | Microfibril-associated glycoprotein 4; Could be involved in calcium-dependent cell adhesion or intercellular interactions. May contribute to the elastic fiber assembly and/or maintenance. | Olfactomedin-like protein 1; Olfactomedin like 1. | 0.429 |
OLFML1 | ABI3BP | ENSP00000332511 | ENSP00000284322 | Olfactomedin-like protein 1; Olfactomedin like 1. | Target of Nesh-SH3; ABI family member 3 binding protein. | 0.406 |
OLFML1 | ADCY4 | ENSP00000332511 | ENSP00000312126 | Olfactomedin-like protein 1; Olfactomedin like 1. | Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | 0.444 |
OLFML1 | ATOH8 | ENSP00000332511 | ENSP00000304676 | Olfactomedin-like protein 1; Olfactomedin like 1. | Protein atonal homolog 8; Transcription factor that binds a palindromic (canonical) core consensus DNA sequence 5'-CANNTG- 3' known as an E-box element, possibly as a heterodimer with other bHLH proteins. Regulates endothelial cell proliferation, migration and tube-like structures formation. Modulates endothelial cell differentiation through NOS3. May be implicated in specification and differentiation of neuronal cell lineages in the brain (By similarity). May participate in kidney development and may be involved in podocyte differentiation (By similarity). During early embryonic devel [...] | 0.444 |
OLFML1 | CTXN1 | ENSP00000332511 | ENSP00000313226 | Olfactomedin-like protein 1; Olfactomedin like 1. | Cortexin-1; May mediate extracellular or intracellular signaling of cortical neurons during forebrain development; Belongs to the cortexin family. | 0.411 |
OLFML1 | DCN | ENSP00000332511 | ENSP00000052754 | Olfactomedin-like protein 1; Olfactomedin like 1. | Decorin; May affect the rate of fibrils formation. | 0.413 |
OLFML1 | DKK2 | ENSP00000332511 | ENSP00000285311 | Olfactomedin-like protein 1; Olfactomedin like 1. | Dickkopf-related protein 2; Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity); Belongs to the dickkopf family. | 0.400 |