node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dole_1107 | Dole_1462 | Dole_1107 | Dole_1462 | TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase class-II; asparagine synthase; KEGG: rca:Rcas_2336 asparagine synthase (glutamine-hydrolyzing). | KEGG: ppd:Ppro_2466 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase class-II; asparagine synthase. | 0.927 |
Dole_1107 | purA | Dole_1107 | Dole_2029 | TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase class-II; asparagine synthase; KEGG: rca:Rcas_2336 asparagine synthase (glutamine-hydrolyzing). | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.916 |
Dole_1107 | pyrB | Dole_1107 | Dole_0514 | TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase class-II; asparagine synthase; KEGG: rca:Rcas_2336 asparagine synthase (glutamine-hydrolyzing). | KEGG: sfu:Sfum_2090 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.916 |
Dole_1462 | Dole_1107 | Dole_1462 | Dole_1107 | KEGG: ppd:Ppro_2466 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase class-II; asparagine synthase. | TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase class-II; asparagine synthase; KEGG: rca:Rcas_2336 asparagine synthase (glutamine-hydrolyzing). | 0.927 |
Dole_1462 | purA | Dole_1462 | Dole_2029 | KEGG: ppd:Ppro_2466 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase class-II; asparagine synthase. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.916 |
Dole_1462 | pyrB | Dole_1462 | Dole_0514 | KEGG: ppd:Ppro_2466 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase class-II; asparagine synthase. | KEGG: sfu:Sfum_2090 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.916 |
carA | carB | Dole_0120 | Dole_0121 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; KEGG: dps:DP3095 probable carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; RimK domain protein ATP-grasp; KEGG: sat:SYN_01625 carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | 0.999 |
carA | carB-2 | Dole_0120 | Dole_1446 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; KEGG: dps:DP3095 probable carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: gme:Gmet_0661 carbamoyl-phosphate synthase, large subunit, glutamine-dependent; Belongs to the CarB family. | 0.999 |
carA | pyrB | Dole_0120 | Dole_0514 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; KEGG: dps:DP3095 probable carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | KEGG: sfu:Sfum_2090 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
carA | pyrC | Dole_0120 | Dole_0515 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; KEGG: dps:DP3095 probable carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.993 |
carA | pyrD | Dole_0120 | Dole_1495 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; KEGG: dps:DP3095 probable carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. | 0.908 |
carA | pyrF | Dole_0120 | Dole_2568 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; KEGG: dps:DP3095 probable carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.903 |
carA | pyrR | Dole_0120 | Dole_3195 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; KEGG: dps:DP3095 probable carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Uracil phosphoribosyltransferase; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | 0.802 |
carB | carA | Dole_0121 | Dole_0120 | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; RimK domain protein ATP-grasp; KEGG: sat:SYN_01625 carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; KEGG: dps:DP3095 probable carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.999 |
carB | carB-2 | Dole_0121 | Dole_1446 | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; RimK domain protein ATP-grasp; KEGG: sat:SYN_01625 carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: gme:Gmet_0661 carbamoyl-phosphate synthase, large subunit, glutamine-dependent; Belongs to the CarB family. | 0.903 |
carB | purA | Dole_0121 | Dole_2029 | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; RimK domain protein ATP-grasp; KEGG: sat:SYN_01625 carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.480 |
carB | pyrB | Dole_0121 | Dole_0514 | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; RimK domain protein ATP-grasp; KEGG: sat:SYN_01625 carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | KEGG: sfu:Sfum_2090 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.998 |
carB | pyrC | Dole_0121 | Dole_0515 | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; RimK domain protein ATP-grasp; KEGG: sat:SYN_01625 carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.984 |
carB | pyrD | Dole_0121 | Dole_1495 | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; RimK domain protein ATP-grasp; KEGG: sat:SYN_01625 carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. | 0.800 |
carB | pyrF | Dole_0121 | Dole_2568 | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; RimK domain protein ATP-grasp; KEGG: sat:SYN_01625 carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.786 |