STRINGSTRING
CAPN7 CAPN7 UBQLNL UBQLNL CAPNS1 CAPNS1 MROH7 MROH7 USP12 USP12 CAST CAST PMPCA PMPCA KDM8 KDM8 CACNA1E CACNA1E TFAP2A TFAP2A BAP1 BAP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
CAPN7Calpain-7; Calcium-regulated non-lysosomal thiol-protease. Belongs to the peptidase C2 family. (769 aa)    
Predicted Functional Partners:
UBQLNL
Ubiquitin-like domain-containing protein.
   
 
 0.829
CAPNS1
Calpain small subunit 1; Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
   
 0.816
MROH7
Uncharacterized protein.
      
 0.776
USP12
Ubiquitin specific peptidase 12; Belongs to the peptidase C19 family.
      
 0.726
CAST
Calpastatin; Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue; Belongs to the protease inhibitor I27 (calpastatin) family.
   
 
 0.721
PMPCA
Peptidase, mitochondrial processing alpha subunit; Belongs to the peptidase M16 family.
   
  
 0.677
KDM8
JmjC domain-containing protein 5 isoform 1.
   
 
 0.621
CACNA1E
Voltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents.
      
 0.611
TFAP2A
Transcription factor AP-2 alpha.
      
 0.571
BAP1
BRCA1 associated protein 1.
      
 0.554
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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