node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AASDH | ACACA | ENSBTAP00000068886 | ENSBTAP00000074493 | Aminoadipate-semialdehyde dehydrogenase. | Acetyl-CoA carboxylase 1; Cytosolic enzyme that catalyzes the carboxylation of acetyl- CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis. This is a 2 steps reaction starting with the ATP- dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA. | 0.627 |
AASDH | ACLY | ENSBTAP00000068886 | ENSBTAP00000059914 | Aminoadipate-semialdehyde dehydrogenase. | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | 0.556 |
AASDH | ACSF3 | ENSBTAP00000068886 | ENSBTAP00000060268 | Aminoadipate-semialdehyde dehydrogenase. | Malonate--CoA ligase ACSF3, mitochondrial; Catalyzes the initial reaction in intramitochondrial fatty acid synthesis, by activating malonate and methylmalonate, but not acetate, into their respective CoA thioester. May have some preference toward very-long-chain substrates; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.595 |
AASDH | ACSL1 | ENSBTAP00000068886 | ENSBTAP00000061904 | Aminoadipate-semialdehyde dehydrogenase. | Acyl-CoA synthetase long chain family member 1. | 0.774 |
AASDH | ACSL3 | ENSBTAP00000068886 | ENSBTAP00000022939 | Aminoadipate-semialdehyde dehydrogenase. | Acyl-CoA synthetase long chain family member 3. | 0.794 |
AASDH | ACSL5 | ENSBTAP00000068886 | ENSBTAP00000053897 | Aminoadipate-semialdehyde dehydrogenase. | Acyl-CoA synthetase long-chain family member 5. | 0.676 |
AASDH | FASN | ENSBTAP00000068886 | ENSBTAP00000021260 | Aminoadipate-semialdehyde dehydrogenase. | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities as an acyl carrier protein. | 0.976 |
AASDH | MCAT | ENSBTAP00000068886 | ENSBTAP00000003130 | Aminoadipate-semialdehyde dehydrogenase. | Malonyl-CoA-acyl carrier protein transacylase. | 0.498 |
AASDH | UNG | ENSBTAP00000068886 | ENSBTAP00000029559 | Aminoadipate-semialdehyde dehydrogenase. | Acetyl-CoA carboxylase beta. | 0.587 |
ACACA | AASDH | ENSBTAP00000074493 | ENSBTAP00000068886 | Acetyl-CoA carboxylase 1; Cytosolic enzyme that catalyzes the carboxylation of acetyl- CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis. This is a 2 steps reaction starting with the ATP- dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA. | Aminoadipate-semialdehyde dehydrogenase. | 0.627 |
ACACA | ACLY | ENSBTAP00000074493 | ENSBTAP00000059914 | Acetyl-CoA carboxylase 1; Cytosolic enzyme that catalyzes the carboxylation of acetyl- CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis. This is a 2 steps reaction starting with the ATP- dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA. | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | 0.987 |
ACACA | ACSF3 | ENSBTAP00000074493 | ENSBTAP00000060268 | Acetyl-CoA carboxylase 1; Cytosolic enzyme that catalyzes the carboxylation of acetyl- CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis. This is a 2 steps reaction starting with the ATP- dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA. | Malonate--CoA ligase ACSF3, mitochondrial; Catalyzes the initial reaction in intramitochondrial fatty acid synthesis, by activating malonate and methylmalonate, but not acetate, into their respective CoA thioester. May have some preference toward very-long-chain substrates; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.938 |
ACACA | ACSL1 | ENSBTAP00000074493 | ENSBTAP00000061904 | Acetyl-CoA carboxylase 1; Cytosolic enzyme that catalyzes the carboxylation of acetyl- CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis. This is a 2 steps reaction starting with the ATP- dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA. | Acyl-CoA synthetase long chain family member 1. | 0.872 |
ACACA | ACSL3 | ENSBTAP00000074493 | ENSBTAP00000022939 | Acetyl-CoA carboxylase 1; Cytosolic enzyme that catalyzes the carboxylation of acetyl- CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis. This is a 2 steps reaction starting with the ATP- dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA. | Acyl-CoA synthetase long chain family member 3. | 0.823 |
ACACA | ACSL5 | ENSBTAP00000074493 | ENSBTAP00000053897 | Acetyl-CoA carboxylase 1; Cytosolic enzyme that catalyzes the carboxylation of acetyl- CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis. This is a 2 steps reaction starting with the ATP- dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA. | Acyl-CoA synthetase long-chain family member 5. | 0.645 |
ACACA | FASN | ENSBTAP00000074493 | ENSBTAP00000021260 | Acetyl-CoA carboxylase 1; Cytosolic enzyme that catalyzes the carboxylation of acetyl- CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis. This is a 2 steps reaction starting with the ATP- dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA. | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities as an acyl carrier protein. | 0.995 |
ACACA | MCAT | ENSBTAP00000074493 | ENSBTAP00000003130 | Acetyl-CoA carboxylase 1; Cytosolic enzyme that catalyzes the carboxylation of acetyl- CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis. This is a 2 steps reaction starting with the ATP- dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA. | Malonyl-CoA-acyl carrier protein transacylase. | 0.978 |
ACACA | UNG | ENSBTAP00000074493 | ENSBTAP00000029559 | Acetyl-CoA carboxylase 1; Cytosolic enzyme that catalyzes the carboxylation of acetyl- CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis. This is a 2 steps reaction starting with the ATP- dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA. | Acetyl-CoA carboxylase beta. | 0.943 |
ACLY | AASDH | ENSBTAP00000059914 | ENSBTAP00000068886 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Aminoadipate-semialdehyde dehydrogenase. | 0.556 |
ACLY | ACACA | ENSBTAP00000059914 | ENSBTAP00000074493 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Acetyl-CoA carboxylase 1; Cytosolic enzyme that catalyzes the carboxylation of acetyl- CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis. This is a 2 steps reaction starting with the ATP- dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA. | 0.987 |