node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACADL | ACADM | ENSBTAP00000013988 | ENSBTAP00000033383 | Acyl-Coenzyme A dehydrogenase, long chain. | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). | 0.967 |
ACADL | ACSBG1 | ENSBTAP00000013988 | ENSBTAP00000058590 | Acyl-Coenzyme A dehydrogenase, long chain. | Long-chain-fatty-acid--CoA ligase ACSBG1; Catalyzes the conversion of fatty acids such as long-chain and very long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation. Can activate diverse saturated, monosaturated and polyunsaturated fatty acids. | 0.540 |
ACADL | ACSL1 | ENSBTAP00000013988 | ENSBTAP00000061904 | Acyl-Coenzyme A dehydrogenase, long chain. | Acyl-CoA synthetase long chain family member 1. | 0.791 |
ACADL | ACSL3 | ENSBTAP00000013988 | ENSBTAP00000022939 | Acyl-Coenzyme A dehydrogenase, long chain. | Acyl-CoA synthetase long chain family member 3. | 0.756 |
ACADL | CPT1A | ENSBTAP00000013988 | ENSBTAP00000058061 | Acyl-Coenzyme A dehydrogenase, long chain. | Carnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. | 0.784 |
ACADL | CPT1B | ENSBTAP00000013988 | ENSBTAP00000021357 | Acyl-Coenzyme A dehydrogenase, long chain. | Carnitine O-palmitoyltransferase 1, muscle isoform. | 0.781 |
ACADL | CPT1C | ENSBTAP00000013988 | ENSBTAP00000066666 | Acyl-Coenzyme A dehydrogenase, long chain. | Carnitine palmitoyltransferase 1C. | 0.531 |
ACADL | CPT2 | ENSBTAP00000013988 | ENSBTAP00000019505 | Acyl-Coenzyme A dehydrogenase, long chain. | Carnitine O-palmitoyltransferase 2, mitochondrial; Belongs to the carnitine/choline acetyltransferase family. | 0.979 |
ACADL | UCP1 | ENSBTAP00000013988 | ENSBTAP00000006097 | Acyl-Coenzyme A dehydrogenase, long chain. | Mitochondrial brown fat uncoupling protein 1; Mitochondrial protein responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates to non-shivering adaptive thermogenesis to temperature and diet variations and more generally to the regulation of energy balance. Functions as a long-chain fatty acid/LCFA and proton symporter, simultaneously transporting one LCFA and one proton through the inner mitochondrial membrane. However, LCFAs remaining associated with the transporter via their hydrophobic tails, it results in an apparent tra [...] | 0.508 |
ACADL | UNG | ENSBTAP00000013988 | ENSBTAP00000029559 | Acyl-Coenzyme A dehydrogenase, long chain. | Acetyl-CoA carboxylase beta. | 0.672 |
ACADM | ACADL | ENSBTAP00000033383 | ENSBTAP00000013988 | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). | Acyl-Coenzyme A dehydrogenase, long chain. | 0.967 |
ACADM | ACSBG1 | ENSBTAP00000033383 | ENSBTAP00000058590 | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). | Long-chain-fatty-acid--CoA ligase ACSBG1; Catalyzes the conversion of fatty acids such as long-chain and very long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation. Can activate diverse saturated, monosaturated and polyunsaturated fatty acids. | 0.527 |
ACADM | ACSL1 | ENSBTAP00000033383 | ENSBTAP00000061904 | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). | Acyl-CoA synthetase long chain family member 1. | 0.771 |
ACADM | ACSL3 | ENSBTAP00000033383 | ENSBTAP00000022939 | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). | Acyl-CoA synthetase long chain family member 3. | 0.673 |
ACADM | CPT1A | ENSBTAP00000033383 | ENSBTAP00000058061 | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). | Carnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. | 0.838 |
ACADM | CPT1B | ENSBTAP00000033383 | ENSBTAP00000021357 | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). | Carnitine O-palmitoyltransferase 1, muscle isoform. | 0.775 |
ACADM | CPT1C | ENSBTAP00000033383 | ENSBTAP00000066666 | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). | Carnitine palmitoyltransferase 1C. | 0.465 |
ACADM | CPT2 | ENSBTAP00000033383 | ENSBTAP00000019505 | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). | Carnitine O-palmitoyltransferase 2, mitochondrial; Belongs to the carnitine/choline acetyltransferase family. | 0.984 |
ACADM | UCP1 | ENSBTAP00000033383 | ENSBTAP00000006097 | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). | Mitochondrial brown fat uncoupling protein 1; Mitochondrial protein responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates to non-shivering adaptive thermogenesis to temperature and diet variations and more generally to the regulation of energy balance. Functions as a long-chain fatty acid/LCFA and proton symporter, simultaneously transporting one LCFA and one proton through the inner mitochondrial membrane. However, LCFAs remaining associated with the transporter via their hydrophobic tails, it results in an apparent tra [...] | 0.548 |
ACADM | UNG | ENSBTAP00000033383 | ENSBTAP00000029559 | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). | Acetyl-CoA carboxylase beta. | 0.692 |