STRINGSTRING
CPT1B CPT1B UNG UNG CPT2 CPT2 CPT1A CPT1A CPT1C CPT1C ACSL1 ACSL1 ACSL3 ACSL3 ACSBG1 ACSBG1 ACADL ACADL UCP1 UCP1 ACADM ACADM
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
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Experiments
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[Homology]
Score
CPT1BCarnitine O-palmitoyltransferase 1, muscle isoform. (771 aa)    
Predicted Functional Partners:
UNG
Acetyl-CoA carboxylase beta.
     
 0.951
CPT2
Carnitine O-palmitoyltransferase 2, mitochondrial; Belongs to the carnitine/choline acetyltransferase family.
  
 
0.941
CPT1A
Carnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family.
  
  
0.904
CPT1C
Carnitine palmitoyltransferase 1C.
  
  
0.903
ACSL1
Acyl-CoA synthetase long chain family member 1.
   
 
 0.870
ACSL3
Acyl-CoA synthetase long chain family member 3.
   
 
 0.812
ACSBG1
Long-chain-fatty-acid--CoA ligase ACSBG1; Catalyzes the conversion of fatty acids such as long-chain and very long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation. Can activate diverse saturated, monosaturated and polyunsaturated fatty acids.
     
 0.796
ACADL
Acyl-Coenzyme A dehydrogenase, long chain.
      
 0.781
UCP1
Mitochondrial brown fat uncoupling protein 1; Mitochondrial protein responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates to non-shivering adaptive thermogenesis to temperature and diet variations and more generally to the regulation of energy balance. Functions as a long-chain fatty acid/LCFA and proton symporter, simultaneously transporting one LCFA and one proton through the inner mitochondrial membrane. However, LCFAs remaining associated with the transporter via their hydrophobic tails, it results in an apparent tra [...]
   
  
 0.777
ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).
      
 0.775
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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