node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALB | BGLAP | ENSBTAP00000022763 | ENSBTAP00000047703 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (Probable). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The sh [...] | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. | 0.689 |
ALB | BMP2 | ENSBTAP00000022763 | ENSBTAP00000006739 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (Probable). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The sh [...] | Bone morphogenetic protein 2. | 0.894 |
ALB | CA10 | ENSBTAP00000022763 | ENSBTAP00000046047 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (Probable). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The sh [...] | Carbonic anhydrase-related protein 10; Does not have a catalytic activity. | 0.546 |
ALB | RUNX2 | ENSBTAP00000022763 | ENSBTAP00000072258 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (Probable). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The sh [...] | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.699 |
ALB | SPP1 | ENSBTAP00000022763 | ENSBTAP00000062863 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (Probable). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The sh [...] | Osteopontin; Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. | 0.750 |
BGLAP | ALB | ENSBTAP00000047703 | ENSBTAP00000022763 | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (Probable). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The sh [...] | 0.689 |
BGLAP | BMP2 | ENSBTAP00000047703 | ENSBTAP00000006739 | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. | Bone morphogenetic protein 2. | 0.891 |
BGLAP | CA10 | ENSBTAP00000047703 | ENSBTAP00000046047 | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. | Carbonic anhydrase-related protein 10; Does not have a catalytic activity. | 0.661 |
BGLAP | RUNX2 | ENSBTAP00000047703 | ENSBTAP00000072258 | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.939 |
BGLAP | SPP1 | ENSBTAP00000047703 | ENSBTAP00000062863 | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. | Osteopontin; Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. | 0.962 |
BMP2 | ALB | ENSBTAP00000006739 | ENSBTAP00000022763 | Bone morphogenetic protein 2. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (Probable). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The sh [...] | 0.894 |
BMP2 | BGLAP | ENSBTAP00000006739 | ENSBTAP00000047703 | Bone morphogenetic protein 2. | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. | 0.891 |
BMP2 | CA10 | ENSBTAP00000006739 | ENSBTAP00000046047 | Bone morphogenetic protein 2. | Carbonic anhydrase-related protein 10; Does not have a catalytic activity. | 0.626 |
BMP2 | RUNX2 | ENSBTAP00000006739 | ENSBTAP00000072258 | Bone morphogenetic protein 2. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.935 |
BMP2 | SPP1 | ENSBTAP00000006739 | ENSBTAP00000062863 | Bone morphogenetic protein 2. | Osteopontin; Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. | 0.923 |
CA10 | ALB | ENSBTAP00000046047 | ENSBTAP00000022763 | Carbonic anhydrase-related protein 10; Does not have a catalytic activity. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (Probable). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The sh [...] | 0.546 |
CA10 | BGLAP | ENSBTAP00000046047 | ENSBTAP00000047703 | Carbonic anhydrase-related protein 10; Does not have a catalytic activity. | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. | 0.661 |
CA10 | BMP2 | ENSBTAP00000046047 | ENSBTAP00000006739 | Carbonic anhydrase-related protein 10; Does not have a catalytic activity. | Bone morphogenetic protein 2. | 0.626 |
CA10 | PRSS48 | ENSBTAP00000046047 | ENSBTAP00000006095 | Carbonic anhydrase-related protein 10; Does not have a catalytic activity. | Serine protease 48; Belongs to the peptidase S1 family. | 0.648 |
CA10 | PURG | ENSBTAP00000046047 | ENSBTAP00000058772 | Carbonic anhydrase-related protein 10; Does not have a catalytic activity. | Purine rich element binding protein G. | 0.620 |