STRINGSTRING
MCIDAS MCIDAS CCNO CCNO GMNN GMNN GMNC GMNC FOXJ1 FOXJ1 RFX2 RFX2 LDLRAD1 LDLRAD1 SHISA8 SHISA8 DEUP1 DEUP1 CDC20B CDC20B RSPH4A RSPH4A
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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MCIDASMulticilin; Transcription regulator specifically required for multiciliate cell differentiation. Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis. Required for the deuterosome-mediated acentriolar pathway. Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Modulates GMNN activity by reducing its affinity for CDT1. (374 aa)    
Predicted Functional Partners:
CCNO
Cyclin O; Belongs to the cyclin family.
 
 
  
 0.852
GMNN
Geminin DNA replication inhibitor.
    
 
0.838
GMNC
Geminin coiled-coil domain containing.
      
 0.796
FOXJ1
Forkhead box J1.
      
 0.782
RFX2
DNA-binding protein RFX2; Transcription factor that acts as a key regulator of spermatogenesis. Acts by regulating expression of genes required for the haploid phase during spermiogenesis, such as genes required for cilium assembly and function. Recognizes and binds the X-box, a regulatory motif with DNA sequence 5'-GTNRCC(0-3N)RGYAAC-3' present on promoters. Probably activates transcription of the testis-specific histone gene HIST1H1T.
      
 0.773
LDLRAD1
Low density lipoprotein receptor class A domain containing 1.
      
 0.693
SHISA8
Shisa family member 8.
      
 0.689
DEUP1
Deuterosome assembly protein 1.
      
 0.668
CDC20B
Cell division cycle 20B.
      
 0.662
RSPH4A
Radial spoke head component 4A.
      
 0.603
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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