STRINGSTRING
APE76848.1 APE76848.1 APE76849.1 APE76849.1 APE76846.1 APE76846.1 APE76847.1 APE76847.1
Network Stats
number of nodes:
11
number of edges:
28
average node degree:
5.09
avg. local clustering coefficient:
0.84
expected number of edges:
30
PPI enrichment p-value:
0.636
your network does not have significantly more
interactions than expected (what does that mean?)
Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight  explain columns
GO-term
description
count in network
strength
signal
false discovery rate
Pentose-phosphate shunt
6 of 14
2.53
5.23
4.93e-11
Reductive pentose-phosphate cycle
4 of 12
2.42
3.15
8.35e-07
D-gluconate metabolic process
2 of 3
2.72
1.53
0.0016
Pentose catabolic process
2 of 4
2.6
1.46
0.0021
Organophosphate metabolic process
7 of 329
1.23
1.45
5.79e-06
(more ...)
 
 
 
 
 
 
Molecular Function (Gene Ontology)
GO-term
description
count in network
strength
signal
false discovery rate
Transketolase activity
4 of 4
2.9
3.8
9.75e-08
D-ribulose-phosphate 3-epimerase activity
2 of 2
2.9
1.4
0.0029
Phosphogluconate dehydrogenase (decarboxylating) activity
2 of 2
2.9
1.4
0.0029
Metal ion binding
7 of 963
0.76
0.53
0.0093
Catalytic activity
11 of 4103
0.33
0.25
0.0328
 
 
 
 
 
 
Cellular Component (Gene Ontology)
GO-term
description
count in network
strength
signal
false discovery rate
Cytosol
8 of 826
0.88
0.81
0.00015
Cytoplasm
10 of 2873
0.44
0.33
0.0105
 
 
 
 
 
 
Reference Publications (PubMed)
publication
(year) title
count in network
strength
signal
false discovery rate
(2020) Horizontal acquisition of a patchwork Calvin cycle by symbiotic and free-living Campylobacterota (formerly Epsilonproteobacteria).
5 of 29
2.13
3.33
1.11e-07
(2021) Metabolic engineering of Escherichia coli for biosynthesis of beta-nicotinamide mononucleotide from nicotinamide.
2 of 10
2.2
0.95
0.0174
 
 
 
 
 
 
Local Network Cluster (STRING)
cluster
description
count in network
strength
signal
false discovery rate
Pentose phosphate pathway, and Glycolysis
11 of 37
2.37
9.43
7.70e-23
Transketolase activity, and Ribulose-phosphate 3-epimerase
7 of 7
2.9
8.13
3.10e-16
Mixed, incl. Glycolysis, and Transketolase activity
8 of 24
2.42
7.22
3.91e-16
Glucose 6-phosphate metabolic process, and ROK family
3 of 13
2.26
2.01
0.00014
 
 
 
 
 
 
pathway
description
count in network
strength
signal
false discovery rate
Pentose phosphate pathway
11 of 62
2.15
7.87
9.11e-22
Carbon metabolism
10 of 277
1.46
2.82
9.64e-13
Biosynthesis of amino acids
8 of 224
1.45
2.43
1.61e-09
Biosynthesis of secondary metabolites
10 of 930
0.93
1.06
7.11e-08
Microbial metabolism in diverse environments
10 of 1111
0.85
0.91
3.27e-07
(more ...)
 
 
 
 
 
 
Subcellular Localization (COMPARTMENTS)
compartment
description
count in network
strength
signal
false discovery rate
Cytosol
7 of 1072
0.71
0.46
0.0175
Cytoplasm
10 of 2237
0.55
0.41
0.0041
 
 
 
 
 
 
keyword
description
count in network
strength
signal
false discovery rate
Thiamine pyrophosphate
3 of 26
1.96
1.66
0.00047
Carbohydrate metabolism
3 of 36
1.82
1.48
0.00088
Magnesium
5 of 153
1.41
1.46
0.00012
Cobalt
2 of 13
2.09
1.12
0.0076
Metal-binding
7 of 481
1.06
1.03
0.00012
(more ...)
 
 
 
 
 
 
Protein Domains (Pfam)
domain
description
count in network
strength
signal
false discovery rate
Transketolase, C-terminal domain
4 of 7
2.66
3.38
4.54e-07
Transketolase, thiamine diphosphate binding domain
3 of 6
2.6
2.27
6.30e-05
Ribulose-phosphate 3 epimerase family
2 of 2
2.9
1.4
0.0029
 
 
 
 
 
 
domain
description
count in network
strength
signal
false discovery rate
Transketolase, C-terminal domain
4 of 7
2.66
3.18
1.16e-06
Transketolase-like, pyrimidine-binding domain
4 of 8
2.6
3.16
1.16e-06
Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II
4 of 13
2.39
2.89
2.77e-06
Transketolase family
3 of 3
2.9
2.58
1.92e-05
Transketolase, bacterial-like
3 of 3
2.9
2.58
1.92e-05
(more ...)
 
 
 
 
 
 
Protein Domains (SMART)
domain
description
count in network
strength
signal
false discovery rate
Transketolase, pyrimidine binding domain
4 of 8
2.6
3.66
1.16e-07
6-phosphogluconate dehydrogenase, C-terminal domain
2 of 2
2.9
1.73
0.00074
 
 
 
 
 
 
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