(6 nodes) Citrate cycle (TCA cycle) network (Nitrosarchaeum koreense)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MY1_0208	Succinate dehydrogenase or fumarate reductase, flavoprotein subunit; COG matches:COG1053; PFAM matches:PF00890, PF02910. (570 aa)
	MY1_0209	Succinate dehydrogenase, subunit D; COG matches:COG2009. (144 aa)
	MY1_0210	Hypothetical protein. (108 aa)
	MY1_0211	Succinate dehydrogenase and fumarate reductase iron-sulfur protein; COG matches:COG0479. (249 aa)
	MY1_1315	Succinate--CoA ligase (ADP-forming); COG matches:COG0045; PFAM matches:PF08442, PF00549. (368 aa)
	sucD	CoA-binding domain protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (305 aa)

Your Current Organism:

Nitrosarchaeum koreense

NCBI taxonomy Id: 1001994
Other names: Candidatus Nitrosoarchaeum koreensis MY1, N. koreense MY1, Nitrosarchaeum koreense MY1, Nitrosopumilus sp. MY1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MY1_0208	MY1_0209	MY1_0208	MY1_0209	Succinate dehydrogenase or fumarate reductase, flavoprotein subunit; COG matches:COG1053; PFAM matches:PF00890, PF02910.	Succinate dehydrogenase, subunit D; COG matches:COG2009.	0.999
MY1_0208	MY1_0210	MY1_0208	MY1_0210	Succinate dehydrogenase or fumarate reductase, flavoprotein subunit; COG matches:COG1053; PFAM matches:PF00890, PF02910.	Hypothetical protein.	0.999
MY1_0208	MY1_0211	MY1_0208	MY1_0211	Succinate dehydrogenase or fumarate reductase, flavoprotein subunit; COG matches:COG1053; PFAM matches:PF00890, PF02910.	Succinate dehydrogenase and fumarate reductase iron-sulfur protein; COG matches:COG0479.	0.999
MY1_0208	MY1_1315	MY1_0208	MY1_1315	Succinate dehydrogenase or fumarate reductase, flavoprotein subunit; COG matches:COG1053; PFAM matches:PF00890, PF02910.	Succinate--CoA ligase (ADP-forming); COG matches:COG0045; PFAM matches:PF08442, PF00549.	0.995
MY1_0208	sucD	MY1_0208	MY1_1316	Succinate dehydrogenase or fumarate reductase, flavoprotein subunit; COG matches:COG1053; PFAM matches:PF00890, PF02910.	CoA-binding domain protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.995
MY1_0209	MY1_0208	MY1_0209	MY1_0208	Succinate dehydrogenase, subunit D; COG matches:COG2009.	Succinate dehydrogenase or fumarate reductase, flavoprotein subunit; COG matches:COG1053; PFAM matches:PF00890, PF02910.	0.999
MY1_0209	MY1_0210	MY1_0209	MY1_0210	Succinate dehydrogenase, subunit D; COG matches:COG2009.	Hypothetical protein.	0.999
MY1_0209	MY1_0211	MY1_0209	MY1_0211	Succinate dehydrogenase, subunit D; COG matches:COG2009.	Succinate dehydrogenase and fumarate reductase iron-sulfur protein; COG matches:COG0479.	0.999
MY1_0209	MY1_1315	MY1_0209	MY1_1315	Succinate dehydrogenase, subunit D; COG matches:COG2009.	Succinate--CoA ligase (ADP-forming); COG matches:COG0045; PFAM matches:PF08442, PF00549.	0.997
MY1_0209	sucD	MY1_0209	MY1_1316	Succinate dehydrogenase, subunit D; COG matches:COG2009.	CoA-binding domain protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.991
MY1_0210	MY1_0208	MY1_0210	MY1_0208	Hypothetical protein.	Succinate dehydrogenase or fumarate reductase, flavoprotein subunit; COG matches:COG1053; PFAM matches:PF00890, PF02910.	0.999
MY1_0210	MY1_0209	MY1_0210	MY1_0209	Hypothetical protein.	Succinate dehydrogenase, subunit D; COG matches:COG2009.	0.999
MY1_0210	MY1_0211	MY1_0210	MY1_0211	Hypothetical protein.	Succinate dehydrogenase and fumarate reductase iron-sulfur protein; COG matches:COG0479.	0.999
MY1_0210	MY1_1315	MY1_0210	MY1_1315	Hypothetical protein.	Succinate--CoA ligase (ADP-forming); COG matches:COG0045; PFAM matches:PF08442, PF00549.	0.993
MY1_0210	sucD	MY1_0210	MY1_1316	Hypothetical protein.	CoA-binding domain protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.976
MY1_0211	MY1_0208	MY1_0211	MY1_0208	Succinate dehydrogenase and fumarate reductase iron-sulfur protein; COG matches:COG0479.	Succinate dehydrogenase or fumarate reductase, flavoprotein subunit; COG matches:COG1053; PFAM matches:PF00890, PF02910.	0.999
MY1_0211	MY1_0209	MY1_0211	MY1_0209	Succinate dehydrogenase and fumarate reductase iron-sulfur protein; COG matches:COG0479.	Succinate dehydrogenase, subunit D; COG matches:COG2009.	0.999
MY1_0211	MY1_0210	MY1_0211	MY1_0210	Succinate dehydrogenase and fumarate reductase iron-sulfur protein; COG matches:COG0479.	Hypothetical protein.	0.999
MY1_0211	MY1_1315	MY1_0211	MY1_1315	Succinate dehydrogenase and fumarate reductase iron-sulfur protein; COG matches:COG0479.	Succinate--CoA ligase (ADP-forming); COG matches:COG0045; PFAM matches:PF08442, PF00549.	0.994
MY1_0211	sucD	MY1_0211	MY1_1316	Succinate dehydrogenase and fumarate reductase iron-sulfur protein; COG matches:COG0479.	CoA-binding domain protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.996