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| | MY1_1435 | Homocysteine S-methyltransferase; COG matches:COG0646; PFAM matches:PF02574. (320 aa) |
| | MY1_1434 | Methionine synthase; COG matches:COG1410; PFAM matches:PF02965, PF02310, PF00809, PF02607. (833 aa) |
| | MY1_1425 | D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COG matches:COG0111; PFAM matches:PF00389, PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (310 aa) |
| | ctaB | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (293 aa) |
| | MY1_1381 | Transcriptional regulator, AsnC family; COG matches:COG1522. (83 aa) |
| | MY1_1374 | YwbE; COG matches:COG4895; PFAM matches:PF09962. (65 aa) |
| | MY1_1370 | Alcohol dehydrogenase GroES domain protein; COG matches:COG1064; PFAM matches:PF08240, PF00107. (343 aa) |
| | MY1_1361 | Hypothetical protein. (355 aa) |
| | MY1_1356 | Beta-lactamase domain protein; COG matches:COG0491; PFAM matches:PF00753. (526 aa) |
| | MY1_1353 | Putative Pentapeptide repeats (8 copies); COG matches:COG2133; PFAM matches:PF07995. (469 aa) |
| | MY1_1340 | YhcX; COG matches:COG0454. (216 aa) |
| | MY1_1337 | Regulatory protein AsnC/Lrp family; COG matches:COG1522. (69 aa) |
| | sucD | CoA-binding domain protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (305 aa) |
| | MY1_1315 | Succinate--CoA ligase (ADP-forming); COG matches:COG0045; PFAM matches:PF08442, PF00549. (368 aa) |
| | purD | Phosphoribosylamine--glycine ligase; COG matches:COG0151; PFAM matches:PF01071, PF02844, PF02843, PF08442; Belongs to the GARS family. (421 aa) |
| | MY1_1306 | Putative Formyl transferase; COG matches:COG0299; PFAM matches:PF00551. (205 aa) |
| | MY1_1276 | Transcriptional regulator; COG matches:COG1522; PFAM matches:PF01037. (81 aa) |
| | MY1_1273 | Hydroxypyruvate reductase; COG matches:COG2379; PFAM matches:PF05161. (425 aa) |
| | MY1_1261 | Citrate synthase; COG matches:COG0372; PFAM matches:PF00285. (387 aa) |
| | MY1_1243 | Acetolactate synthase; COG matches:COG0028; PFAM matches:PF02776, PF02775, PF00205. (565 aa) |
| | MY1_1242 | Acetolactate synthase, small subunit; COG matches:COG0440; PFAM matches:PF10369, PF01842. (160 aa) |
| | MY1_1241 | Isopropylmalate/citramalate/homocitrate synthase; COG matches:COG0119; PFAM matches:PF00682, PF08502; Belongs to the alpha-IPM synthase/homocitrate synthase family. (504 aa) |
| | MY1_1240 | Isopropylmalate/isohomocitrate dehydrogenase; COG matches:COG0473; PFAM matches:PF00180. (337 aa) |
| | MY1_1207 | Rossmann-fold oxidoreductase; COG matches:COG1028; PFAM matches:PF00106, PF08659, PF01370. (594 aa) |
| | fbp | Fructose-16-bisphosphatase type V archaeal; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (378 aa) |
| | tuf | Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (432 aa) |
| | MY1_1187 | Putative ubiE/COQ5 methyltransferase family protein; COG matches:COG2226; PFAM matches:PF01209, PF08242, PF05175, PF08241, PF06325. (227 aa) |
| | MY1_1186 | Hypothetical protein. (227 aa) |
| | MY1_1185 | Putative 2-isopropylmalate synthase; COG matches:COG0119. (80 aa) |
| | MY1_1181 | Putative O-methyltransferase; COG matches:COG4122; PFAM matches:PF01596. (210 aa) |
| | MY1_1175 | Mannose-6-phosphate isomerase-like protein; COG matches:COG0662; PFAM matches:PF07883. (120 aa) |
| | MY1_1170 | Aminotransferase class-III; COG matches:COG0001; PFAM matches:PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (432 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (332 aa) |
| | MY1_1126 | Pyruvate, phosphate dikinase; COG matches:COG0574; PFAM matches:PF02896, PF01326, PF00391. (951 aa) |
| | MY1_1124 | Transcriptional regulator; COG matches:COG1522. (79 aa) |
| | MY1_1123 | Transcriptional regulator, AsnC family; COG matches:COG1522; PFAM matches:PF01037. (176 aa) |
| | MY1_1120 | Transcriptional regulator, AsnC family; COG matches:COG1522; PFAM matches:PF01037. (147 aa) |
| | MY1_1119 | Hypothetical protein. (153 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (219 aa) |
| | MY1_1077 | UbiA prenyltransferase; COG matches:COG1575; PFAM matches:PF01040. (257 aa) |
| | MY1_1073 | Asparagine synthase; COG matches:COG0367; PFAM matches:PF00733. (314 aa) |
| | trpA | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (267 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (396 aa) |
| | MY1_1052 | Indole-3-glycerol-phosphate synthase; COG matches:COG0134; PFAM matches:PF00218. (258 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (348 aa) |
| | MY1_1050 | Glutamine amidotransferase of anthranilate synthase; COG matches:COG0512; PFAM matches:PF00117. (197 aa) |
| | MY1_1049 | Anthranilate synthase; COG matches:COG0147; PFAM matches:PF00425, PF04715. (449 aa) |
| | ilvD | Dihydroxy-acid dehydratase; COG matches:COG0129; PFAM matches:PF00920; Belongs to the IlvD/Edd family. (557 aa) |
| | MY1_1011 | Putative AsnC family protein; COG matches:COG1522; PFAM matches:PF01037. (174 aa) |
| | MY1_0996 | High-affinity Fe2+/Pb2+ permease; COG matches:COG0672; PFAM matches:PF03239. (735 aa) |
| | purP | 5-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl 5'-monophosphate synthetase; Catalyzes the ATP- and formate-dependent formylation of 5- aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates. (341 aa) |
| | MY1_0986 | AMP-dependent synthetase and ligase; COG matches:COG0365; PFAM matches:PF00501, PF11930. (640 aa) |
| | MY1_0953 | Transcriptional regulator, AsnC family; COG matches:COG1522. (72 aa) |
| | MY1_0946 | Threonine dehydratase; COG matches:COG1171; PFAM matches:PF00291. (402 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (170 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (380 aa) |
| | MY1_0939 | Nucleotidyl transferase; COG matches:COG1208; PFAM matches:PF00483. (223 aa) |
| | MY1_0936 | Propanoyl-CoA C-acyltransferase; COG matches:COG0183; PFAM matches:PF02803. (369 aa) |
| | MY1_0935 | Hypothetical protein. (105 aa) |
| | MY1_0928 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (445 aa) |
| | MY1_0927 | Hemolysin; COG matches:COG1253; PFAM matches:PF01595, PF03471. (417 aa) |
| | MY1_0926 | Glyceraldehyde-3-phosphate dehydrogenase (NAD(P)(+)) (Phosphorylating); COG matches:COG0057. (350 aa) |
| | MY1_0919 | Hydroxymethylglutaryl-CoA synthase; COG matches:COG3425; PFAM matches:PF01154, PF08540. (464 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; COG matches:COG0152; PFAM matches:PF01259; Belongs to the SAICAR synthetase family. (274 aa) |
| | MY1_0866 | Transcriptional regulator; COG matches:COG1522; PFAM matches:PF01037. (81 aa) |
| | purF | Glutamine amidotransferase class-II; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (477 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (721 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (210 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (87 aa) |
| | ubiX | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (187 aa) |
| | MY1_0847 | IMP biosynthesis enzyme PurP domain protein; COG matches:COG1759; PFAM matches:PF06973, PF06849. (363 aa) |
| | mqnD | Periplasmic solute-binding protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. (275 aa) |
| | MY1_0807 | Aminotransferase class I and II; COG matches:COG0436; PFAM matches:PF00155. (451 aa) |
| | MY1_0806 | Hypothetical protein; COG matches:COG3205. (80 aa) |
| | MY1_0799 | Radical SAM domain protein; COG matches:COG1060; PFAM matches:PF04055. (365 aa) |
| | MY1_0792 | Transcriptional regulator, AsnC family; COG matches:COG1522; PFAM matches:PF01037. (147 aa) |
| | MY1_0758 | Regulatory protein AsnC/Lrp family; COG matches:COG1522. (69 aa) |
| | MY1_0733 | Hypothetical protein. (48 aa) |
| | MY1_0723 | Acetate--CoA ligase; COG matches:COG0365; PFAM matches:PF00501, PF11930. (638 aa) |
| | MY1_0701 | Homoserine dehydrogenase; COG matches:COG0460; PFAM matches:PF00742, PF00208. (336 aa) |
| | MY1_0700 | PUA domain containing protein; COG matches:COG2016; PFAM matches:PF01472. (158 aa) |
| | MY1_0690 | Phosphoglycolate phosphatase; COG matches:COG0561; PFAM matches:PF08282. (231 aa) |
| | MY1_0661 | Phosphoserine phosphatase SerB; COG matches:COG0560; PFAM matches:PF00702. (216 aa) |
| | MY1_0653 | Myo-inositol-1-phosphate synthase; COG matches:COG1260; PFAM matches:PF07994, PF01658. (364 aa) |
| | MY1_0602 | Hypothetical protein. (492 aa) |
| | map | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily. (298 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase; COG matches:COG0150; PFAM matches:PF02769, PF00586. (340 aa) |
| | MY1_0544 | UbiD family decarboxylase; COG matches:COG0043; PFAM matches:PF01977. (480 aa) |
| | mqnC | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (372 aa) |
| | aroA-2 | Putative phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. (262 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family. (353 aa) |
| | aroD | 3-dehydroquinate dehydratase, type I; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (224 aa) |
| | aroE | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (273 aa) |
| | aroK | Shikimate kinase; COG matches:COG1685; PFAM matches:PF00288. (284 aa) |
| | aroA | Putative 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (422 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (365 aa) |
| | MY1_0535 | Aminotransferase class I and II; COG matches:COG0436; PFAM matches:PF00155, PF01817, PF00266, PF01053. (456 aa) |
| | MY1_0534 | Prephenate dehydrogenase; COG matches:COG0287; PFAM matches:PF02153. (284 aa) |
| | MY1_0528 | Nucleotidyl transferase; COG matches:COG1208; PFAM matches:PF00483. (233 aa) |
| | MY1_0524 | Phosphoglycerate mutase; COG matches:COG3635; PFAM matches:PF10143, PF01676. (421 aa) |
| | MY1_0494 | Transcriptional Regulator, AsnC family; COG matches:COG1522. (166 aa) |
| | MY1_0492 | Alcohol dehydrogenase GroES domain protein; COG matches:COG1064; PFAM matches:PF08240, PF00107. (350 aa) |
| | MY1_0483 | Chlorite dismutase; COG matches:COG3253; PFAM matches:PF06778. (201 aa) |
| | MY1_0479 | Putative transcriptional regulator, AsnC family; COG matches:COG1522. (342 aa) |
| | MY1_0478 | Siroheme synthase; COG matches:COG1648. (217 aa) |
| | hemA-2 | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (421 aa) |
| | MY1_0476 | Delta-aminolevulinic acid dehydratase; COG matches:COG0113; PFAM matches:PF00490; Belongs to the ALAD family. (327 aa) |
| | MY1_0473 | DUF1722 domain containing protein; COG matches:COG3272; PFAM matches:PF08349. (181 aa) |
| | MY1_0471 | NAD-dependent epimerase/dehydratase; COG matches:COG0702; PFAM matches:PF01370, PF05368, PF01073, PF02719. (459 aa) |
| | pgk | Phosphoglycerate kinase; COG matches:COG0126; PFAM matches:PF00162; Belongs to the phosphoglycerate kinase family. (403 aa) |
| | MY1_0448 | Uroporphyrinogen III synthase HEM4; COG matches:COG1587; PFAM matches:PF02602. (266 aa) |
| | MY1_0447 | Uroporphyrin-III C-methyltransferase; COG matches:COG0007; PFAM matches:PF00590; Belongs to the precorrin methyltransferase family. (249 aa) |
| | hemC | Putative porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (311 aa) |
| | hemL | Glutamate-1-semialdehyde 2,1-aminomutase; COG matches:COG0001; PFAM matches:PF00202. (425 aa) |
| | MY1_0405 | Nucleotide binding protein, PINc; COG matches:COG1439. (168 aa) |
| | MY1_0385 | Nucleotidyl transferase; COG matches:COG1208; PFAM matches:PF00483. (241 aa) |
| | MY1_0384 | 3-isopropylmalate dehydratase, small subunit; COG matches:COG0066; PFAM matches:PF00694. (194 aa) |
| | MY1_0383 | 3-isopropylmalate dehydratase, large subunit; COG matches:COG0065; PFAM matches:PF00330. (471 aa) |
| | MY1_0382 | 3-isopropylmalate dehydratase, small subunit; COG matches:COG0066; PFAM matches:PF00694. (161 aa) |
| | leuC | 3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (423 aa) |
| | MY1_0375 | Pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; COG matches:COG1013; PFAM matches:PF02775, PF12367. (290 aa) |
| | MY1_0374 | Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COG matches:COG0674; PFAM matches:PF01855, PF01558. (636 aa) |
| | MY1_0372 | Glyoxylate reductase; COG matches:COG1052; PFAM matches:PF00389, PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (330 aa) |
| | adkA | Adenylate kinase; COG matches:COG2019; Belongs to the archaeal adenylate kinase family. (184 aa) |
| | MY1_0353 | Ornithine carbamoyltransferase; COG matches:COG0078; PFAM matches:PF02729, PF00185; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (303 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (538 aa) |
| | MY1_0340 | Transcriptional regulator, AsnC family; COG matches:COG1522; PFAM matches:PF01037. (143 aa) |
| | MY1_0301 | ExsB family protein; COG matches:COG1606; PFAM matches:PF06508, PF01171. (248 aa) |
| | MY1_0299 | Malate dehydrogenase; COG matches:COG0039; PFAM matches:PF00056, PF02866; Belongs to the LDH/MDH superfamily. (304 aa) |
| | MY1_0297 | Radical SAM domain protein; COG matches:COG1032; PFAM matches:PF04055. (511 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (412 aa) |
| | mvk | Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (315 aa) |
| | MY1_0272 | Aspartate/glutamate/uridylate kinase; COG matches:COG1608; PFAM matches:PF00696. (250 aa) |
| | MY1_0271 | Isopentenyl-diphosphate delta-isomerase, type 1; COG matches:COG1443; PFAM matches:PF00293. (213 aa) |
| | MY1_0270 | Polyprenyl synthetase; COG matches:COG0142; PFAM matches:PF00348; Belongs to the FPP/GGPP synthase family. (326 aa) |
| | gltX | Glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (568 aa) |
| | tal | Putative transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (223 aa) |
| | MY1_0254 | Transketolase central region; COG matches:COG3958; PFAM matches:PF02779, PF02780. (324 aa) |
| | MY1_0253 | Ribulose-phosphate 3-epimerase; COG matches:COG3959; PFAM matches:PF00456, PF00834, PF00676. (555 aa) |
| | MY1_0246 | Ribosomal-protein-alanine acetyltransferase; COG matches:COG0456; PFAM matches:PF00583. (141 aa) |
| | MY1_0239 | Polyprenyl synthetase; COG matches:COG0142; PFAM matches:PF00348; Belongs to the FPP/GGPP synthase family. (283 aa) |
| | MY1_0220 | Inositol-phosphate phosphatase; COG matches:COG0483; PFAM matches:PF00459. (266 aa) |
| | hemA | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (358 aa) |
| | argH | Argininosuccinate lyase; COG matches:COG0165; PFAM matches:PF00206. (486 aa) |
| | MY1_0212 | Metal-sulfur cluster biosynthetic enzyme; COG matches:COG2151; PFAM matches:PF01883. (107 aa) |
| | MY1_0211 | Succinate dehydrogenase and fumarate reductase iron-sulfur protein; COG matches:COG0479. (249 aa) |
| | MY1_0210 | Hypothetical protein. (108 aa) |
| | MY1_0209 | Succinate dehydrogenase, subunit D; COG matches:COG2009. (144 aa) |
| | MY1_0208 | Succinate dehydrogenase or fumarate reductase, flavoprotein subunit; COG matches:COG1053; PFAM matches:PF00890, PF02910. (570 aa) |
| | MY1_0206 | Putative methylisocitrate lyase; COG matches:COG2513; PFAM matches:PF00463. (282 aa) |
| | ilvE-2 | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (305 aa) |
| | ndk | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (133 aa) |
| | MY1_0173 | Phosphoglucosamine mutase; COG matches:COG1109; PFAM matches:PF02878, PF02880, PF02879, PF00408; Belongs to the phosphohexose mutase family. (456 aa) |
| | MY1_0167 | Ribose 5-phosphate isomerase; COG matches:COG0120; PFAM matches:PF06026. (224 aa) |
| | MY1_0152 | Radical SAM domain protein; COG matches:COG1032; PFAM matches:PF04055. (293 aa) |
| | MY1_0141 | Aspartate/glutamate/uridylate kinase; COG matches:COG0527; PFAM matches:PF00696. (471 aa) |
| | ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (337 aa) |
| | MY1_0137 | Methyltransferase type 11; COG matches:COG0500; PFAM matches:PF08241, PF08242. (184 aa) |
| | MY1_0131 | Heme A synthase; COG matches:COG1612; PFAM matches:PF02628. (130 aa) |
| | MY1_0126 | Phosphoglycerate mutase; COG matches:COG0406; PFAM matches:PF00300. (207 aa) |
| | MY1_0122 | Aminotransferase class I and II; COG matches:COG0436; PFAM matches:PF00155, PF01041, PF01053, PF00266. (390 aa) |
| | MY1_0116 | Short-chain dehydrogenase/reductase SDR; COG matches:COG1028. (215 aa) |
| | MY1_0113 | Glucose-6-phosphate isomerase; COG matches:COG0166; PFAM matches:PF10432. (341 aa) |
| | MY1_0098 | Hydrolase domain containing protein; PFAM matches:PF00702. (214 aa) |
| | MY1_0095 | Putative Pentapeptide repeats (8 copies); COG matches:COG2133; PFAM matches:PF07995. (436 aa) |
| | MY1_0091 | C-methyltransferase; COG matches:COG2423; PFAM matches:PF08484, PF08421, PF08242. (390 aa) |
| | MY1_0090 | dTDP-4-dehydrorhamnose 3,5-epimerase; COG matches:COG1898; PFAM matches:PF00908. (138 aa) |
| | MY1_0089 | dTDP-4-dehydrorhamnose reductase; COG matches:COG1091; PFAM matches:PF04321, PF01370, PF02719, PF01073, PF07993. (296 aa) |
| | MY1_0082 | dTDP-4-dehydrorhamnose reductase; COG matches:COG1091; PFAM matches:PF04321, PF01370, PF01073, PF02719, PF07993. (240 aa) |
| | MY1_0075 | Radical SAM domain protein; COG matches:COG1032; PFAM matches:PF04055, PF02310. (480 aa) |
| | MY1_0070 | Asparagine synthase (Glutamine-hydrolyzing); COG matches:COG0367; PFAM matches:PF00733. (401 aa) |
| | MY1_0069 | Methyltransferase; COG matches:COG0500; PFAM matches:PF08241, PF08242. (339 aa) |
| | MY1_0064 | Methyltransferase; COG matches:COG0500; PFAM matches:PF08241, PF08242. (252 aa) |
| | MY1_0061 | Asparagine synthase (Glutamine-hydrolyzing); COG matches:COG0367; PFAM matches:PF00733. (355 aa) |
| | MY1_0053 | Putative cytoplasmic protein; COG matches:COG1134; PFAM matches:PF01894. (139 aa) |
| | MY1_0025 | Methionine adenosyltransferase; COG matches:COG0192; PFAM matches:PF02773, PF02772, PF00438. (388 aa) |
| | MY1_0024 | NAD-dependent epimerase/dehydratase; COG matches:COG1271; PFAM matches:PF01370, PF01073, PF07993. (289 aa) |
| | sat | Putative ATP-sulfurylase; COG matches:COG2046; PFAM matches:PF01747; Belongs to the sulfate adenylyltransferase family. (378 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (307 aa) |
| | MY1_1939 | Short-chain dehydrogenase/reductase SDR; COG matches:COG1028; PFAM matches:PF00106. (251 aa) |
| | MY1_1913 | Hypothetical protein. (217 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (443 aa) |
| | MY1_1891 | Short-chain dehydrogenase/reductase SDR; COG matches:COG4221; PFAM matches:PF00106, PF08659; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (246 aa) |
| | MY1_1879 | Ribose-phosphate pyrophosphokinase; COG matches:COG0462; PFAM matches:PF00156; Belongs to the ribose-phosphate pyrophosphokinase family. (292 aa) |
| | MY1_1874 | Lactate/malate dehydrogenase; COG matches:COG0039; PFAM matches:PF02866, PF00056; Belongs to the LDH/MDH superfamily. (300 aa) |
| | MY1_1863 | Transcriptional regulator, AsnC family; COG matches:COG1522. (85 aa) |
| | MY1_1853 | Aspartokinase; COG matches:COG0527; PFAM matches:PF00696, PF01842; Belongs to the aspartokinase family. (467 aa) |
| | MY1_1824 | Serine--pyruvate transaminase; COG matches:COG0075; PFAM matches:PF00266. (381 aa) |
| | MY1_1815 | Methyltransferase type 11; COG matches:COG0500; PFAM matches:PF01209, PF08241, PF08242. (280 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (279 aa) |
| | MY1_1774 | Putative transcriptional regulator, CopG family; COG matches:COG0864; PFAM matches:PF08753. (127 aa) |
| | MY1_1755 | Propanoyl-CoA C-acyltransferase; COG matches:COG0183; PFAM matches:PF00108. (384 aa) |
| | MY1_1754 | Nucleic-acid-binding protein; COG matches:COG1545; PFAM matches:PF01796. (122 aa) |
| | MY1_1745 | DNA-binding TFAR19-related protein; COG matches:COG2118; PFAM matches:PF01984; Belongs to the PDCD5 family. (91 aa) |
| | MY1_1738 | Riboflavin synthase, alpha subunit; COG matches:COG0307; PFAM matches:PF00677. (195 aa) |
| | MY1_1737 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (221 aa) |
| | MY1_1736 | 6,7-dimethyl-8-ribityllumazine synthase; COG matches:COG0054; PFAM matches:PF00885. (121 aa) |
| | ctaB-2 | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (309 aa) |
| | MY1_1708 | Transcriptional regulator, AsnC family; COG matches:COG1522; PFAM matches:PF01037. (155 aa) |
| | MY1_1707 | Aspartate-semialdehyde dehydrogenase; COG matches:COG0136; PFAM matches:PF02774, PF01118. (360 aa) |
| | MY1_1697 | ROK family protein; COG matches:COG1940; PFAM matches:PF00480. (285 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (477 aa) |
| | MY1_1687 | Prephenate dehydratase; COG matches:COG0077; PFAM matches:PF00800. (271 aa) |
| | MY1_1680 | Glucose sorbosone dehydrogenase; COG matches:COG2133; PFAM matches:PF07995. (364 aa) |
| | MY1_1679 | Hydroxymethylglutaryl-CoA reductase, degradative; COG matches:COG1257; PFAM matches:PF00368; Belongs to the HMG-CoA reductase family. (419 aa) |
| | MY1_1677 | ATP phosphoribosyltransferase; COG matches:COG0040; PFAM matches:PF01634, PF08029. (325 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (423 aa) |
| | MY1_1675 | Aminotransferase class I and II; COG matches:COG0079; PFAM matches:PF00155. (356 aa) |
| | MY1_1674 | Haloacid dehalogenase domain protein hydrolase; COG matches:COG0546; PFAM matches:PF00702. (313 aa) |
| | MY1_1673 | Imidazoleglycerol-phosphate dehydratase; COG matches:COG0131; PFAM matches:PF00475. (146 aa) |
| | hisH | Putative glutamine amidotransferase class-I; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (201 aa) |
| | hisA | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; COG matches:COG0106; PFAM matches:PF00977. (235 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (267 aa) |
| | hisI | Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (110 aa) |
| | MY1_1667 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (412 aa) |
| | MY1_1652 | Putative Shikimate kinase; COG matches:COG1936. (182 aa) |
| | MY1_1641 | Transcriptional regulator, AsnC family; COG matches:COG1522; PFAM matches:PF01037. (175 aa) |
| | MY1_1630 | Pyridoxal-5'-phosphate-dependent protein beta subunit; COG matches:COG0031; PFAM matches:PF00291. (492 aa) |
| | MY1_1596 | Transcriptional regulator; COG matches:COG1522; PFAM matches:PF01037. (84 aa) |
| | MY1_1593 | Aconitate hydratase; COG matches:COG1048; PFAM matches:PF00330, PF00694. (754 aa) |
| | MY1_1584 | Asparagine synthase; COG matches:COG0367; PFAM matches:PF00733. (251 aa) |
| | MY1_1583 | Adenylosuccinate lyase; COG matches:COG0015; PFAM matches:PF00206, PF10397. (453 aa) |
| | MY1_1575 | Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; COG matches:COG1109; PFAM matches:PF02878, PF02880, PF02879. (384 aa) |
| | MY1_1523 | Radical SAM domain protein; COG matches:COG1032; PFAM matches:PF04055. (532 aa) |
| | MY1_1513 | Isocitrate dehydrogenase (NAD(+)); COG matches:COG0473; PFAM matches:PF00180. (336 aa) |
| | MY1_1469 | Putative short chain dehydrogenase; COG matches:COG1028; PFAM matches:PF00106, PF08643; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (276 aa) |
| | MY1_1463 | Methyltransferase type 11; COG matches:COG2226; PFAM matches:PF08241, PF01209. (229 aa) |
| | MY1_1452 | Cytidyltransferase-related domain-containing protein; COG matches:COG0615; PFAM matches:PF01467. (205 aa) |
| | MY1_1451 | Diphthine synthase; COG matches:COG1798; PFAM matches:PF00590, PF04010. (345 aa) |
| | MY1_1446 | Transcriptional regulator, AsnC family; COG matches:COG1522; PFAM matches:PF01037. (139 aa) |
| | lysJ | Acetylornithine and succinylornithine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. (385 aa) |
| | lysZ | Acetylglutamate/acetylaminoadipate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily. (267 aa) |
| | lysY | N-acetyl-gamma-glutamyl-phosphate/N-acetyl- gamma-aminoadipyl- phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. (349 aa) |
| | argG | Argininosuccinate synthase; COG matches:COG0137; PFAM matches:PF00764; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (399 aa) |
