STRINGSTRING
Flna Flna Dcp1a Dcp1a H2ax H2ax Ncoa3 Ncoa3 Vps35 Vps35 Serpinh1 Serpinh1 Prrx1 Prrx1 Myh9 Myh9 Smarca5 Smarca5 Smarcd1 Smarcd1 Eif4b Eif4b Parg Parg Smc1a Smc1a Myh10 Myh10 Ddx5 Ddx5 Med1 Med1 Kat6b Kat6b Xrn2 Xrn2 Hsp90b1 Hsp90b1 Adam12 Adam12 Ncor2 Ncor2 Mcm3 Mcm3 Tln1 Tln1 Rbpj Rbpj Pgd Pgd Stub1 Stub1 Ppm1g Ppm1g Acaca Acaca Top2b Top2b Pds5b Pds5b Gli2 Gli2 Uba2 Uba2 Baz2a Baz2a Huwe1 Huwe1 Eif4g1 Eif4g1 Hat1 Hat1 Brd7 Brd7 Sin3a Sin3a Flnc Flnc Shmt2 Shmt2 Khdrbs1 Khdrbs1 Wasl Wasl Kdm2a Kdm2a Mcrs1 Mcrs1 Rad9a Rad9a Samhd1 Samhd1 Baz1b Baz1b Rela Rela Dhx9 Dhx9 Mcm6 Mcm6 Flnb Flnb Hdac2 Hdac2 Kat6a Kat6a Adam19 Adam19 Fxr2 Fxr2 Taf1 Taf1 Pnkp Pnkp Eps15 Eps15 Srsf1 Srsf1 Supt5 Supt5 Msn Msn Ranbp2 Ranbp2 LOC106000030 LOC106000030 Cntln Cntln ENSDORP00000016214 ENSDORP00000016214 LOC106000028 LOC106000028 ENSDORP00000016447 ENSDORP00000016447 Foxo3 Foxo3 Epha2 Epha2 Zyx Zyx Smc4 Smc4 G3bp2 G3bp2 Smg1 Smg1 Cavin1 Cavin1 Tpx2 Tpx2 Rbbp4 Rbbp4 Ctnnd1 Ctnnd1 ENSDORP00000018236 ENSDORP00000018236 Frs2 Frs2 Smchd1 Smchd1 Atrx Atrx Igf2r Igf2r LOC106000027 LOC106000027 ENSDORP00000019242 ENSDORP00000019242 Kmt2c Kmt2c P4ha2 P4ha2 ENSDORP00000019608 ENSDORP00000019608 Kif2a Kif2a ENSDORP00000019812 ENSDORP00000019812 Eif4a1 Eif4a1 Bhlhe40 Bhlhe40 Hsf1 Hsf1 Tbc1d15 Tbc1d15 Hmga1 Hmga1 Hdac4 Hdac4 Crebbp Crebbp Kmt2d Kmt2d LOC105997010 LOC105997010 ENSDORP00000022892 ENSDORP00000022892 LOC105996995 LOC105996995 Hmga2 Hmga2 Nipbl Nipbl H2bc3 H2bc3 Trp53 Trp53 H2bc18 H2bc18 Lrp1 Lrp1 Abi1 Abi1 Hcfc1 Hcfc1 LOC105996996 LOC105996996 ENSDORP00000024945 ENSDORP00000024945 Pcbp1 Pcbp1 Rpa1 Rpa1 Arhgdia Arhgdia Myc Myc Fosl2 Fosl2 LOC105994671 LOC105994671 Smarcc1 Smarcc1 Mecp2 Mecp2 LOC105996994 LOC105996994 Tigar Tigar Lig1 Lig1 ENSDORP00000027720 ENSDORP00000027720 Emd Emd
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Flnafilamin-A isoform X1. (2647 aa)
Dcp1amRNA-decapping enzyme 1A isoform X1. (603 aa)
H2axHistone H2A; Belongs to the histone H2A family. (143 aa)
Ncoa3Nuclear receptor coactivator 3. (1412 aa)
Vps35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (764 aa)
Serpinh1Serpin H1; Belongs to the serpin family. (201 aa)
Prrx1Paired mesoderm homeobox protein 1. (132 aa)
Myh9Myosin-9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1960 aa)
Smarca5SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5. (959 aa)
Smarcd1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (515 aa)
Eif4bEukaryotic translation initiation factor 4B isoform X4. (614 aa)
Pargpoly(ADP-ribose) glycohydrolase. (943 aa)
Smc1aStructural maintenance of chromosomes protein 1A. (990 aa)
Myh10Myosin-10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1976 aa)
Ddx5Probable ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family. (614 aa)
Med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1546 aa)
Kat6bHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (79 aa)
Xrn25'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (931 aa)
Hsp90b1Endoplasmin. (804 aa)
Adam12Disintegrin and metalloproteinase domain-containing protein 12. (884 aa)
Ncor2Nuclear receptor corepressor 2. (2240 aa)
Mcm3DNA helicase; Belongs to the MCM family. (815 aa)
Tln1Talin-1 isoform X2. (2541 aa)
RbpjRecombining binding protein suppressor of hairless isoform X1. (526 aa)
Pgd6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (483 aa)
Stub1E3 ubiquitin-protein ligase CHIP. (267 aa)
Ppm1gProtein phosphatase 1G. (541 aa)
Acacaacetyl-CoA carboxylase 1 isoform X1. (2346 aa)
Top2bDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1607 aa)
Pds5bSister chromatid cohesion protein PDS5 homolog B isoform X1. (1449 aa)
Gli2Zinc finger protein GLI2. (1549 aa)
Uba2SUMO-activating enzyme subunit 2. (538 aa)
Baz2aBromodomain adjacent to zinc finger domain protein 2A isoform X1. (1886 aa)
Huwe1E3 ubiquitin-protein ligase HUWE1 isoform X1. (4373 aa)
Eif4g1Eukaryotic translation initiation factor 4 gamma 1 isoform X2. (1306 aa)
Hat1Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. (419 aa)
Brd7Bromodomain-containing protein 7. (652 aa)
Sin3aPaired amphipathic helix protein Sin3a. (1274 aa)
Flncfilamin-C isoform X1. (2726 aa)
Shmt2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa)
Khdrbs1KH domain-containing, RNA-binding, signal transduction-associated protein 1. (441 aa)
WaslNeural Wiskott-Aldrich syndrome protein. (506 aa)
Kdm2aLysine-specific demethylase 2A. (1112 aa)
Mcrs1Microspherule protein 1 isoform X2. (450 aa)
Rad9aCell cycle checkpoint control protein; Belongs to the rad9 family. (389 aa)
Samhd1Deoxynucleoside triphosphate triphosphohydrolase SAMHD1. (503 aa)
Baz1bTyrosine-protein kinase BAZ1B. (1476 aa)
RelaTranscription factor p65 isoform X1. (236 aa)
Dhx9ATP-dependent RNA helicase A. (1375 aa)
Mcm6DNA helicase; Belongs to the MCM family. (749 aa)
Flnbfilamin-B isoform X2. (2591 aa)
Hdac2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa)
Kat6aHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (886 aa)
Adam19Disintegrin and metalloproteinase domain-containing protein 19. (849 aa)
Fxr2Fragile X mental retardation syndrome-related protein 2. (647 aa)
Taf1Transcription initiation factor TFIID subunit. (1831 aa)
PnkpBifunctional polynucleotide phosphatase/kinase. (524 aa)
Eps15Epidermal growth factor receptor substrate 15. (880 aa)
Srsf1Serine/arginine-rich splicing factor 1. (253 aa)
Supt5Transcription elongation factor SPT5. (1041 aa)
MsnMoesin. (583 aa)
Ranbp2E3 SUMO-protein ligase RanBP2 isoform X1. (3090 aa)
LOC106000030Histone H2B; Belongs to the histone H2B family. (126 aa)
CntlnCentlein. (262 aa)
ENSDORP00000016214annotation not available (94 aa)
LOC106000028Histone H2B type 1. (126 aa)
ENSDORP00000016447annotation not available (183 aa)
Foxo3Forkhead box protein O3. (672 aa)
Epha2Ephrin type-A receptor 2 isoform X2. (976 aa)
ZyxZyxin. (559 aa)
Smc4Structural maintenance of chromosomes protein. (1279 aa)
G3bp2Ras GTPase-activating protein-binding protein 2 isoform X1. (483 aa)
Smg1Serine/threonine-protein kinase SMG1; Belongs to the PI3/PI4-kinase family. (3643 aa)
Cavin1Polymerase I and transcript release factor. (391 aa)
Tpx2Targeting protein for Xklp2. (587 aa)
Rbbp4Histone-binding protein RBBP4. (425 aa)
Ctnnd1Catenin delta-1 isoform X1. (964 aa)
ENSDORP00000018236annotation not available (218 aa)
Frs2Fibroblast growth factor receptor substrate 2. (507 aa)
Smchd1Structural maintenance of chromosomes flexible hinge domain-containing protein 1. (1911 aa)
AtrxTranscriptional regulator ATRX isoform X1. (2472 aa)
Igf2rCation-independent mannose-6-phosphate receptor. (2410 aa)
LOC106000027Histone H2B type 1. (126 aa)
ENSDORP00000019242annotation not available (209 aa)
Kmt2cHistone-lysine N-methyltransferase 2C. (328 aa)
P4ha2Prolyl 4-hydroxylase subunit alpha-2 isoform X4. (535 aa)
ENSDORP00000019608annotation not available (164 aa)
Kif2aKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (722 aa)
ENSDORP00000019812annotation not available (107 aa)
Eif4a1Eukaryotic initiation factor 4A-I; Belongs to the DEAD box helicase family. (406 aa)
Bhlhe40Class E basic helix-loop-helix protein 40. (412 aa)
Hsf1Heat shock factor protein 1. (512 aa)
Tbc1d15TBC1 domain family member 15 isoform X2. (673 aa)
Hmga1High mobility group protein HMG-I/HMG-Y isoform X1. (107 aa)
Hdac4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1062 aa)
CrebbpCREB-binding protein. (2432 aa)
Kmt2dHistone-lysine N-methyltransferase 2D. (774 aa)
LOC105997010Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSDORP00000022892annotation not available (166 aa)
LOC105996995Histone H2B type 1. (126 aa)
Hmga2High mobility group protein HMGI-C. (108 aa)
NipblNipped-B protein. (2804 aa)
H2bc3Histone H2B; Belongs to the histone H2B family. (126 aa)
Trp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (356 aa)
H2bc18Histone H2B; Belongs to the histone H2B family. (126 aa)
Lrp1Prolow-density lipoprotein receptor-related protein 1. (4543 aa)
Abi1Abl interactor 1 isoform X1. (461 aa)
Hcfc1Host cell factor 1 isoform X1. (2086 aa)
LOC105996996Histone H2B type 1. (126 aa)
ENSDORP00000024945annotation not available (210 aa)
Pcbp1poly(RC)-binding protein 1. (356 aa)
Rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
ArhgdiaRho GDP-dissociation inhibitor 1. (204 aa)
MycMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (435 aa)
Fosl2Fos-related antigen 2. (327 aa)
LOC105994671Chromobox protein homolog 3. (173 aa)
Smarcc1SWI/SNF complex subunit SMARCC1. (1061 aa)
Mecp2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (500 aa)
LOC105996994Histone H2B type 1. (126 aa)
TigarFructose-2,6-bisphosphatase TIGAR. (244 aa)
Lig1DNA ligase. (912 aa)
ENSDORP00000027720annotation not available (121 aa)
EmdEmerin. (255 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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