(153 nodes) Spliceosomal complex, and DEAD/DEAH box helicase domain network (Dipodomys ordii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Crnkl1	Crooked neck-like protein 1. (693 aa)
	Prpf18	pre-mRNA-splicing factor 18. (342 aa)
	Snrpa1	U2 small nuclear ribonucleoprotein A. (235 aa)
	Lsm6	U6 snRNA-associated Sm-like protein LSm6. (80 aa)
	Pprc1	Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 isoform X1. (1624 aa)
	Syf2	pre-mRNA-splicing factor SYF2. (244 aa)
	Snrpd2	Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (118 aa)
	Snrnp35	U11/U12 small nuclear ribonucleoprotein 35 kDa protein. (246 aa)
	Sf3b1	Splicing factor 3B subunit 1. (1260 aa)
	Sf3b2	Splicing factor 3B subunit 2. (879 aa)
	LOC105985762	Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (110 aa)
	Lrmda	Leucine-rich repeat-containing protein C10orf11 homolog isoform X1. (227 aa)
	Cwc25	pre-mRNA-splicing factor CWC25 homolog. (422 aa)
	Shb	SH2 domain-containing adapter protein B. (509 aa)
	Cactin	Cactin, spliceosome C complex subunit. (447 aa)
	Snrnp40	U5 small nuclear ribonucleoprotein 40 kDa protein. (358 aa)
	Zcchc17	Nucleolar protein of 40 kDa. (152 aa)
	Ddx42	ATP-dependent RNA helicase DDX42. (889 aa)
	Lrrc51	Leucine-rich repeat-containing protein 51. (192 aa)
	Snrpn	Small nuclear ribonucleoprotein-associated protein. (240 aa)
	Ppie	Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (301 aa)
	Txnl4b	Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (149 aa)
	Dhx38	pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16. (1228 aa)
	Rbm22	pre-mRNA-splicing factor RBM22. (358 aa)
	Prpf6	pre-mRNA-processing factor 6. (856 aa)
	Sf3a1	Splicing factor 3A subunit 1. (793 aa)
	ENSDORP00000005261	annotation not available (68 aa)
	Zmat5	Zinc finger matrin-type protein 5. (170 aa)
	Sf3b5	Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
	Snrnp200	U5 small nuclear ribonucleoprotein 200 kDa helicase. (2110 aa)
	Prkrip1	PRKR-interacting protein 1. (188 aa)
	Htatsf1	HIV Tat-specific factor 1. (188 aa)
	Prpf8	pre-mRNA-processing-splicing factor 8. (1966 aa)
	Slu7	pre-mRNA-splicing factor SLU7. (536 aa)
	Tfip11	Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (837 aa)
	Ubl5	Ubiquitin-like protein 5. (73 aa)
	Yju2	Coiled-coil domain-containing protein 94. (315 aa)
	Snrpa	U1 small nuclear ribonucleoprotein A. (284 aa)
	Isy1	pre-mRNA-splicing factor ISY1 homolog. (277 aa)
	Lsm3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (114 aa)
	Prpf19	pre-mRNA-processing factor 19. (504 aa)
	Ddx50	ATP-dependent RNA helicase DDX50 isoform X1. (737 aa)
	Ppwd1	Peptidylprolyl isomerase domain and WD repeat-containing protein 1 isoform X1. (646 aa)
	Ppil3	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (160 aa)
	Lsm10	U7 snRNA-associated Sm-like protein LSm10. (123 aa)
	Wbp4	WW domain-binding protein 4. (332 aa)
	Dhx32	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32. (711 aa)
	Prpf31	U4/U6 small nuclear ribonucleoprotein Prp31. (499 aa)
	Snrpd1	Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (119 aa)
	Dhx34	LOW QUALITY PROTEIN: probable ATP-dependent RNA helicase DHX34. (1140 aa)
	Cwf19l2	CWF19-like protein 2. (116 aa)
	Prpf3	U4/U6 small nuclear ribonucleoprotein Prp3. (634 aa)
	Cdc5l	Cell division cycle 5-like protein. (802 aa)
	Xab2	pre-mRNA-splicing factor SYF1 isoform X1. (855 aa)
	Sf3b6	Splicing factor 3B subunit 6. (125 aa)
	Snrnp27	U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein. (156 aa)
	Snrnp70	U1 small nuclear ribonucleoprotein 70 kDa. (442 aa)
	Cwc15	Spliceosome-associated protein CWC15 homolog. (227 aa)
	Cwc22	pre-mRNA-splicing factor CWC22 homolog. (907 aa)
	Snw1	SNW domain-containing protein 1. (539 aa)
	Spaca6	Uncharacterized protein LOC105994184. (324 aa)
	Ddx23	Probable ATP-dependent RNA helicase DDX23. (820 aa)
	Tcerg1l	Transcription elongation regulator 1-like protein. (512 aa)
	Mfap1	Microfibrillar-associated protein 1. (439 aa)
	Wdr25	WD repeat-containing protein 25. (537 aa)
	Sf3b3	Splicing factor 3B subunit 3. (1217 aa)
	Bcas2	pre-mRNA-splicing factor SPF27 isoform X1. (225 aa)
	Srrm3	Serine/arginine repetitive matrix protein 3. (121 aa)
	Sf3a2	Splicing factor 3A subunit 2. (463 aa)
	Zmat2	Zinc finger matrin-type protein 2. (171 aa)
	Hfm1	Probable ATP-dependent DNA helicase HFM1. (1454 aa)
	ENSDORP00000014116	annotation not available (71 aa)
	Snrnp48	U11/U12 small nuclear ribonucleoprotein 48 kDa protein. (340 aa)
	Ddx51	ATP-dependent RNA helicase DDX51; Belongs to the DEAD box helicase family. (170 aa)
	Aqr	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1464 aa)
	Plrg1	Pleiotropic regulator 1. (507 aa)
	Sf3b4	Splicing factor 3B subunit 4 isoform X2. (424 aa)
	Ccdc12	Coiled-coil domain-containing protein 12. (165 aa)
	Pqbp1	Polyglutamine-binding protein 1. (268 aa)
	ENSDORP00000016171	annotation not available (154 aa)
	Rbm42	RNA-binding protein 42 isoform X1. (478 aa)
	Snrpe	Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (92 aa)
	Lsm4	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (139 aa)
	ENSDORP00000016957	annotation not available (128 aa)
	Ik	Protein Red. (557 aa)
	Zcrb1	Zinc finger CCHC-type and RNA-binding motif-containing protein 1. (175 aa)
	ENSDORP00000017391	annotation not available (282 aa)
	ENSDORP00000017605	annotation not available (182 aa)
	Dhx8	ATP-dependent RNA helicase DHX8. (1183 aa)
	Nkapl	NKAP-like protein. (377 aa)
	BC024978	UPF0692 protein C19orf54 homolog. (343 aa)
	Wdr70	WD repeat-containing protein 70 isoform X2. (641 aa)
	ENSDORP00000018014	annotation not available (122 aa)
	Dnajc5	dnaJ homolog subfamily C member 5. (198 aa)
	Ctnnbl1	Beta-catenin-like protein 1 isoform X1. (563 aa)
	ENSDORP00000018504	annotation not available (282 aa)
	Lsm8	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
	Lsm5	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa)
	LOC105999785	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (174 aa)
	ENSDORP00000019128	annotation not available (173 aa)
	Parpbp	PCNA-interacting partner isoform X1. (132 aa)
	ENSDORP00000019253	annotation not available (506 aa)
	LOC106002817	Protein BUD31 homolog. (107 aa)
	ENSDORP00000019922	annotation not available (152 aa)
	Fam32a	Protein FAM32A isoform X2. (104 aa)
	Ddx46	Probable ATP-dependent RNA helicase DDX46. (983 aa)
	Prpf4	U4/U6 small nuclear ribonucleoprotein Prp4. (521 aa)
	ENSDORP00000020910	annotation not available (72 aa)
	Rbm41	RNA-binding protein 41 isoform X1. (434 aa)
	LOC105986255	Crooked neck-like protein 1. (677 aa)
	ENSDORP00000021263	annotation not available (92 aa)
	ENSDORP00000021463	annotation not available (108 aa)
	LOC106002076	Small nuclear ribonucleoprotein F. (82 aa)
	ENSDORP00000021845	annotation not available (52 aa)
	Dhx57	Putative ATP-dependent RNA helicase DHX57. (1375 aa)
	Snrpb	Small nuclear ribonucleoprotein-associated protein. (230 aa)
	ENSDORP00000022466	annotation not available (107 aa)
	Eftud2	116 kDa U5 small nuclear ribonucleoprotein component. (972 aa)
	Snrpg	Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
	Daw1	Dynein assembly factor with WDR repeat domains 1. (415 aa)
	Snrpb2	U2 small nuclear ribonucleoprotein B'. (225 aa)
	Usp39	U4/U6.U5 tri-snRNP-associated protein 2. (568 aa)
	Lsm2	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
	Txnl4a	Thioredoxin-like protein 4A. (71 aa)
	ENSDORP00000023181	annotation not available (92 aa)
	Ppih	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (177 aa)
	Rnpc3	RNA-binding protein 40. (515 aa)
	ENSDORP00000023286	annotation not available (584 aa)
	Wbp11	WW domain-binding protein 11. (32 aa)
	Wdr53	WD repeat-containing protein 53 isoform X2. (360 aa)
	ENSDORP00000023499	annotation not available (74 aa)
	Sf3a3	Splicing factor 3A subunit 3. (501 aa)
	ENSDORP00000023787	annotation not available (137 aa)
	LOC106001022	Crooked neck-like protein 1. (677 aa)
	ENSDORP00000024082	annotation not available (126 aa)
	Cdc40	pre-mRNA-processing factor 17 isoform X1. (579 aa)
	Prpf38a	pre-mRNA-splicing factor 38A. (270 aa)
	Smu1	WD40 repeat-containing protein SMU1. (495 aa)
	ENSDORP00000024643	annotation not available (76 aa)
	ENSDORP00000024666	annotation not available (89 aa)
	LOC106002143	Small nuclear ribonucleoprotein F-like. (43 aa)
	ENSDORP00000024924	annotation not available (177 aa)
	Phf5a	PHD finger-like domain-containing protein 5A. (110 aa)
	Bud31	Protein BUD31 homolog. (144 aa)
	Lsm1	U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation. (133 aa)
	Dhx35	Probable ATP-dependent RNA helicase DHX35. (703 aa)
	ENSDORP00000026285	annotation not available (59 aa)
	Ppil1	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa)
	Dhx36	ATP-dependent RNA helicase DHX36 isoform X1. (981 aa)
	ENSDORP00000027310	annotation not available (70 aa)
	Lsm7	U6 snRNA-associated Sm-like protein LSm7. (102 aa)
	Sart1	U4/U6.U5 tri-snRNP-associated protein 1. (772 aa)
	Tcerg1	Transcription elongation regulator 1 isoform X2. (1112 aa)

Your Current Organism:

Dipodomys ordii

NCBI taxonomy Id: 10020
Other names: D. ordii

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Aqr	Bcas2	ENSDORP00000014268	ENSDORP00000013371	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	pre-mRNA-splicing factor SPF27 isoform X1.	0.969
Aqr	Bud31	ENSDORP00000014268	ENSDORP00000025503	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Protein BUD31 homolog.	0.971
Aqr	Cactin	ENSDORP00000014268	ENSDORP00000003825	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Cactin, spliceosome C complex subunit.	0.738
Aqr	Cdc40	ENSDORP00000014268	ENSDORP00000024487	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	pre-mRNA-processing factor 17 isoform X1.	0.988
Aqr	Cdc5l	ENSDORP00000014268	ENSDORP00000008575	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Cell division cycle 5-like protein.	0.993
Aqr	Crnkl1	ENSDORP00000014268	ENSDORP00000000371	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Crooked neck-like protein 1.	0.976
Aqr	Ctnnbl1	ENSDORP00000014268	ENSDORP00000018364	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Beta-catenin-like protein 1 isoform X1.	0.738
Aqr	Cwc15	ENSDORP00000014268	ENSDORP00000010408	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Spliceosome-associated protein CWC15 homolog.	0.938
Aqr	Cwc22	ENSDORP00000014268	ENSDORP00000010792	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	pre-mRNA-splicing factor CWC22 homolog.	0.926
Aqr	Cwc25	ENSDORP00000014268	ENSDORP00000002874	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	pre-mRNA-splicing factor CWC25 homolog.	0.739
Aqr	Cwf19l2	ENSDORP00000014268	ENSDORP00000008067	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	CWF19-like protein 2.	0.932
Aqr	Ddx23	ENSDORP00000014268	ENSDORP00000011903	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Probable ATP-dependent RNA helicase DDX23.	0.652
Aqr	Ddx42	ENSDORP00000014268	ENSDORP00000003923	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	ATP-dependent RNA helicase DDX42.	0.459
Aqr	Ddx46	ENSDORP00000014268	ENSDORP00000020600	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Probable ATP-dependent RNA helicase DDX46.	0.459
Aqr	Ddx50	ENSDORP00000014268	ENSDORP00000006854	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	ATP-dependent RNA helicase DDX50 isoform X1.	0.421
Aqr	Ddx51	ENSDORP00000014268	ENSDORP00000014266	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	ATP-dependent RNA helicase DDX51; Belongs to the DEAD box helicase family.	0.419
Aqr	Dhx32	ENSDORP00000014268	ENSDORP00000007511	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32.	0.699
Aqr	Dhx34	ENSDORP00000014268	ENSDORP00000007921	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	LOW QUALITY PROTEIN: probable ATP-dependent RNA helicase DHX34.	0.884
Aqr	Dhx35	ENSDORP00000014268	ENSDORP00000026167	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Probable ATP-dependent RNA helicase DHX35.	0.785
Aqr	Dhx36	ENSDORP00000014268	ENSDORP00000027215	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	ATP-dependent RNA helicase DHX36 isoform X1.	0.480