STRINGSTRING
Lck Lck Syk Syk Lyn Lyn Erbb3 Erbb3 Ptpn6 Ptpn6 Shc2 Shc2 Vav3 Vav3 Sos1 Sos1 Yes1 Yes1 Cd3e Cd3e Cd3d Cd3d Dock1 Dock1 Rapgef1 Rapgef1 Shc1 Shc1 Mast3 Mast3 Ptk6 Ptk6 Pik3r6 Pik3r6 Grap Grap Shc3 Shc3 Pik3cb Pik3cb Zap70 Zap70 Dock4 Dock4 Cass4 Cass4 Ptpn11 Ptpn11 Rac2 Rac2 Pik3ca Pik3ca Ptk2b Ptk2b Cblb Cblb Pik3cg Pik3cg Shc4 Shc4 Ptpn18 Ptpn18 Itk Itk Elmo2 Elmo2 Inppl1 Inppl1 Tgfb1i1 Tgfb1i1 Plce1 Plce1 Vav2 Vav2 Plcg1 Plcg1 Irs1 Irs1 Pik3cd Pik3cd Irs4 Irs4 Csk Csk Mst1r Mst1r Rac1 Rac1 Erbb2 Erbb2 Rras Rras Elmo3 Elmo3 Fgr Fgr Inpp5d Inpp5d Kalrn Kalrn Grap2 Grap2 Gab1 Gab1 Lat Lat Plcg2 Plcg2 Src Src Lcp2 Lcp2 Fyn Fyn Tec Tec Clnk Clnk Cd3g Cd3g Pik3r3 Pik3r3 Lpxn Lpxn Rras2 Rras2 Rhof Rhof Dock2 Dock2 Rhog Rhog Ptk2 Ptk2 Met Met Pik3r1 Pik3r1 Dock3 Dock3 Vav1 Vav1 Sos2 Sos2 Crkl Crkl Txk Txk LOC106000559 LOC106000559 Pik3r5 Pik3r5 Axl Axl Crk Crk Nras Nras Bmx Bmx Nedd9 Nedd9 Cd247 Cd247 Pag1 Pag1 Rhoj Rhoj LOC105996454 LOC105996454 Pdgfrb Pdgfrb Hck Hck Rasgrf1 Rasgrf1 Btk Btk Matk Matk Bcar1 Bcar1 Sh2d1a Sh2d1a Blnk Blnk Grb2 Grb2 Nrarp Nrarp
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LckTyrosine-protein kinase. (509 aa)
SykTyrosine-protein kinase. (633 aa)
LynTyrosine-protein kinase. (512 aa)
Erbb3Receptor tyrosine-protein kinase erbB-3. (1339 aa)
Ptpn6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
Shc2SHC-transforming protein 2. (513 aa)
Vav3Guanine nucleotide exchange factor VAV3. (847 aa)
Sos1Son of sevenless homolog 1. (1301 aa)
Yes1Tyrosine-protein kinase. (541 aa)
Cd3eT-cell surface glycoprotein CD3 epsilon chain. (190 aa)
Cd3dT-cell surface glycoprotein CD3 delta chain. (167 aa)
Dock1Dedicator of cytokinesis protein 1 isoform X2; Belongs to the DOCK family. (1870 aa)
Rapgef1Rap guanine nucleotide exchange factor 1 isoform X1. (1198 aa)
Shc1SHC-transforming protein 1 isoform X2. (473 aa)
Mast3Microtubule associated serine/threonine kinase 3. (71 aa)
Ptk6Tyrosine-protein kinase. (451 aa)
Pik3r6LOW QUALITY PROTEIN: phosphoinositide 3-kinase regulatory subunit 6. (682 aa)
GrapGRB2-related adapter protein isoform X1. (217 aa)
Shc3SHC-transforming protein 3. (598 aa)
Pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
Zap70Tyrosine-protein kinase. (618 aa)
Dock4Dedicator of cytokinesis protein 4; Belongs to the DOCK family. (1971 aa)
Cass4Cas scaffolding protein family member 4. (743 aa)
Ptpn11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (583 aa)
Rac2Ras-related C3 botulinum toxin substrate 2. (184 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Ptk2bProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
CblbE3 ubiquitin-protein ligase CBL-B isoform X2. (939 aa)
Pik3cgPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1; Belongs to the PI3/PI4-kinase family. (264 aa)
Shc4SHC-transforming protein 4. (340 aa)
Ptpn18Tyrosine-protein phosphatase non-receptor type 18 isoform X1. (455 aa)
ItkTyrosine-protein kinase. (620 aa)
Elmo2Engulfment and cell motility protein 2 isoform X1. (732 aa)
Inppl1Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2. (1240 aa)
Tgfb1i1Transforming growth factor beta-1-induced transcript 1 protein; Belongs to the paxillin family. (462 aa)
Plce1Phosphoinositide phospholipase C. (2291 aa)
Vav2Guanine nucleotide exchange factor VAV2. (766 aa)
Plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
Irs1Insulin receptor substrate 1. (1239 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
Irs4Insulin receptor substrate 4. (1262 aa)
CskTyrosine-protein kinase. (450 aa)
Mst1rMacrophage-stimulating protein receptor isoform X1. (266 aa)
Rac1Ras-related C3 botulinum toxin substrate 1. (187 aa)
Erbb2Receptor protein-tyrosine kinase. (1255 aa)
RrasRas-related protein R-Ras. (218 aa)
Elmo3Engulfment and cell motility protein 3 isoform X1. (719 aa)
FgrTyrosine-protein kinase. (527 aa)
Inpp5dPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1. (1186 aa)
KalrnKalirin isoform X2. (2981 aa)
Grap2GRB2-related adapter protein 2 isoform X2. (324 aa)
Gab1GRB2-associated-binding protein 1. (707 aa)
LatLinker for activation of T-cells family member 1 isoform X1. (234 aa)
Plcg2Phosphoinositide phospholipase C. (1065 aa)
SrcTyrosine-protein kinase. (539 aa)
Lcp2Lymphocyte cytosolic protein 2. (314 aa)
FynTyrosine-protein kinase. (518 aa)
TecTyrosine-protein kinase. (631 aa)
ClnkCytokine-dependent hematopoietic cell linker. (370 aa)
Cd3gT-cell surface glycoprotein CD3 gamma chain. (180 aa)
Pik3r3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
LpxnLeupaxin; Belongs to the paxillin family. (386 aa)
Rras2Ras-related protein R-Ras2 isoform X1. (171 aa)
RhofRho-related GTP-binding protein RhoF. (194 aa)
Dock2Dedicator of cytokinesis protein 2-like; Belongs to the DOCK family. (1727 aa)
RhogRho-related GTP-binding protein RhoG. (191 aa)
Ptk2Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1072 aa)
MetHepatocyte growth factor receptor. (1382 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
Dock3Dedicator of cytokinesis protein 3; Belongs to the DOCK family. (2017 aa)
Vav1Proto-oncogene vav. (845 aa)
Sos2Son of sevenless homolog 2. (1320 aa)
CrklCrk-like protein. (303 aa)
TxkTyrosine-protein kinase. (527 aa)
LOC106000559Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
Pik3r5Phosphoinositide 3-kinase regulatory subunit 5 isoform X1. (872 aa)
AxlTyrosine-protein kinase receptor UFO. (858 aa)
CrkAdapter molecule crk. (304 aa)
NrasGTPase NRas. (189 aa)
BmxTyrosine-protein kinase. (623 aa)
Nedd9Enhancer of filamentation 1 isoform X3. (834 aa)
Cd247T-cell surface glycoprotein CD3 zeta chain isoform X1. (164 aa)
Pag1Phosphoprotein associated with glycosphingolipid-enriched microdomains 1. (433 aa)
RhojRho-related GTP-binding protein RhoJ isoform X2. (169 aa)
LOC105996454Low affinity immunoglobulin gamma Fc region receptor II-like. (311 aa)
PdgfrbPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1098 aa)
HckTyrosine-protein kinase. (526 aa)
Rasgrf1Ras-specific guanine nucleotide-releasing factor 1. (1234 aa)
BtkTyrosine-protein kinase. (659 aa)
MatkTyrosine-protein kinase. (484 aa)
Bcar1Breast cancer anti-estrogen resistance protein 1 isoform X1. (931 aa)
Sh2d1aSH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. (126 aa)
BlnkB-cell linker protein. (427 aa)
Grb2Growth factor receptor-bound protein 2. (217 aa)
NrarpNotch-regulated ankyrin repeat-containing protein. (114 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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