STRINGSTRING
Erbb3 Erbb3 Sos1 Sos1 Shc1 Shc1 Shc3 Shc3 Ptpn11 Ptpn11 Shc4 Shc4 Erbb2 Erbb2 Gab1 Gab1 Met Met Sos2 Sos2 Grb2 Grb2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Erbb3Receptor tyrosine-protein kinase erbB-3. (1339 aa)
Sos1Son of sevenless homolog 1. (1301 aa)
Shc1SHC-transforming protein 1 isoform X2. (473 aa)
Shc3SHC-transforming protein 3. (598 aa)
Ptpn11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (583 aa)
Shc4SHC-transforming protein 4. (340 aa)
Erbb2Receptor protein-tyrosine kinase. (1255 aa)
Gab1GRB2-associated-binding protein 1. (707 aa)
MetHepatocyte growth factor receptor. (1382 aa)
Sos2Son of sevenless homolog 2. (1320 aa)
Grb2Growth factor receptor-bound protein 2. (217 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.