(35 nodes) TRP channels, and Store-operated calcium entry network (Dipodomys ordii)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	9530068E07Rik	Keratinocyte-associated transmembrane protein 2. (255 aa)
	Trpm7	Transient receptor potential cation channel subfamily M member 7. (1863 aa)
	Trpm8	Transient receptor potential cation channel subfamily M member 8. (1055 aa)
	Trpm5	Transient receptor potential cation channel subfamily M member 5. (1148 aa)
	Cacna1i	Voltage-dependent T-type calcium channel subunit alpha-1I. (2201 aa)
	Trpc6	Short transient receptor potential channel 6. (513 aa)
	Trpv4	Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (869 aa)
	Mcoln1	Mucolipin-1. (609 aa)
	Trpv2	Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (753 aa)
	Cacna1g	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2385 aa)
	Trpc4	Short transient receptor potential channel 4 isoform X2; Belongs to the transient receptor (TC 1.A.4) family. (978 aa)
	Trpv3	Transient receptor potential cation channel subfamily V member 3 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (790 aa)
	Trpv1	Transient receptor potential cation channel subfamily V member 1 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (841 aa)
	Trpm3	Transient receptor potential cation channel subfamily M member 3 isoform X3. (1699 aa)
	Prkce	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (548 aa)
	Orai3	Protein orai-3. (248 aa)
	Trpc7	Short transient receptor potential channel 7 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (862 aa)
	Trpc5	Short transient receptor potential channel 5; Belongs to the transient receptor (TC 1.A.4) family. (966 aa)
	Trpc1	Short transient receptor potential channel 1. (756 aa)
	Mcoln2	Mucolipin-2 isoform X1. (564 aa)
	Mcoln3	Mucolipin-3 isoform X1. (553 aa)
	Trpc3	Short transient receptor potential channel 3 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (836 aa)
	Stim2	Stromal interaction molecule 2. (566 aa)
	Orai2	Protein orai-2. (250 aa)
	Trpa1	Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1081 aa)
	Prkch	Protein kinase C. (645 aa)
	Stim2-2	Stromal interaction molecule 2. (85 aa)
	Cacna1h	Voltage-dependent T-type calcium channel subunit alpha-1H. (2166 aa)
	Trpm1-2	Transient receptor potential cation channel subfamily M member 1. (388 aa)
	Stim1	Stromal interaction molecule 1 isoform X2. (685 aa)
	ENSDORP00000023167	annotation not available (153 aa)
	Trpm4	Transient receptor potential cation channel subfamily M member 4. (1206 aa)
	Trpv5	Transient receptor potential cation channel subfamily V member 5; Belongs to the transient receptor (TC 1.A.4) family. (723 aa)
	ENSDORP00000026631	annotation not available (111 aa)
	Orai1	Calcium release-activated calcium channel protein 1. (300 aa)

Your Current Organism:

Dipodomys ordii

NCBI taxonomy Id: 10020
Other names: D. ordii

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
9530068E07Rik	Stim1	ENSDORP00000000665	ENSDORP00000023026	Keratinocyte-associated transmembrane protein 2.	Stromal interaction molecule 1 isoform X2.	0.565
9530068E07Rik	Stim2	ENSDORP00000000665	ENSDORP00000015626	Keratinocyte-associated transmembrane protein 2.	Stromal interaction molecule 2.	0.565
9530068E07Rik	Stim2-2	ENSDORP00000000665	ENSDORP00000020812	Keratinocyte-associated transmembrane protein 2.	Stromal interaction molecule 2.	0.565
9530068E07Rik	Trpa1	ENSDORP00000000665	ENSDORP00000017166	Keratinocyte-associated transmembrane protein 2.	Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family.	0.441
Cacna1g	Cacna1h	ENSDORP00000008577	ENSDORP00000021896	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	Voltage-dependent T-type calcium channel subunit alpha-1H.	0.911
Cacna1g	Cacna1i	ENSDORP00000008577	ENSDORP00000004757	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	Voltage-dependent T-type calcium channel subunit alpha-1I.	0.922
Cacna1g	Trpc1	ENSDORP00000008577	ENSDORP00000013121	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	Short transient receptor potential channel 1.	0.859
Cacna1g	Trpc3	ENSDORP00000008577	ENSDORP00000014908	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	Short transient receptor potential channel 3 isoform X1; Belongs to the transient receptor (TC 1.A.4) family.	0.434
Cacna1g	Trpc4	ENSDORP00000008577	ENSDORP00000008684	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	Short transient receptor potential channel 4 isoform X2; Belongs to the transient receptor (TC 1.A.4) family.	0.857
Cacna1g	Trpc5	ENSDORP00000008577	ENSDORP00000011579	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	Short transient receptor potential channel 5; Belongs to the transient receptor (TC 1.A.4) family.	0.857
Cacna1g	Trpc6	ENSDORP00000008577	ENSDORP00000005103	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	Short transient receptor potential channel 6.	0.421
Cacna1g	Trpc7	ENSDORP00000008577	ENSDORP00000010461	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	Short transient receptor potential channel 7 isoform X1; Belongs to the transient receptor (TC 1.A.4) family.	0.421
Cacna1h	Cacna1g	ENSDORP00000021896	ENSDORP00000008577	Voltage-dependent T-type calcium channel subunit alpha-1H.	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	0.911
Cacna1h	Cacna1i	ENSDORP00000021896	ENSDORP00000004757	Voltage-dependent T-type calcium channel subunit alpha-1H.	Voltage-dependent T-type calcium channel subunit alpha-1I.	0.938
Cacna1h	Trpc1	ENSDORP00000021896	ENSDORP00000013121	Voltage-dependent T-type calcium channel subunit alpha-1H.	Short transient receptor potential channel 1.	0.860
Cacna1h	Trpc3	ENSDORP00000021896	ENSDORP00000014908	Voltage-dependent T-type calcium channel subunit alpha-1H.	Short transient receptor potential channel 3 isoform X1; Belongs to the transient receptor (TC 1.A.4) family.	0.427
Cacna1h	Trpc4	ENSDORP00000021896	ENSDORP00000008684	Voltage-dependent T-type calcium channel subunit alpha-1H.	Short transient receptor potential channel 4 isoform X2; Belongs to the transient receptor (TC 1.A.4) family.	0.857
Cacna1h	Trpc5	ENSDORP00000021896	ENSDORP00000011579	Voltage-dependent T-type calcium channel subunit alpha-1H.	Short transient receptor potential channel 5; Belongs to the transient receptor (TC 1.A.4) family.	0.857
Cacna1h	Trpc6	ENSDORP00000021896	ENSDORP00000005103	Voltage-dependent T-type calcium channel subunit alpha-1H.	Short transient receptor potential channel 6.	0.426
Cacna1h	Trpc7	ENSDORP00000021896	ENSDORP00000010461	Voltage-dependent T-type calcium channel subunit alpha-1H.	Short transient receptor potential channel 7 isoform X1; Belongs to the transient receptor (TC 1.A.4) family.	0.421