STRINGSTRING
Ift57 Ift57 Mthfd1l Mthfd1l Kdm2b Kdm2b Tsc2 Tsc2 Mthfr Mthfr Setd2 Setd2 Opa1 Opa1 Prkaca Prkaca Mthfd1 Mthfd1 Deaf1 Deaf1 Sema4c Sema4c Tgif1 Tgif1 Fuz Fuz Sfrp1 Sfrp1 Brd2 Brd2 Scrib Scrib Gatad2a Gatad2a Zeb2 Zeb2 Rarg Rarg Traf6 Traf6 Cc2d2a Cc2d2a Abl2 Abl2 Folr1 Folr1 Tfap2a Tfap2a Tbxt Tbxt Sall4 Sall4 Plxnb2 Plxnb2 Trim71 Trim71 Ift122 Ift122 Pax2 Pax2 Fzd1 Fzd1 Fzd6 Fzd6 Dvl2 Dvl2 Dvl3 Dvl3 Stil Stil St14 St14 Sall1 Sall1 Tgfb2 Tgfb2 Tgfb1 Tgfb1 Phactr4 Phactr4 Lrp6 Lrp6 Sec24b Sec24b Tmed2 Tmed2 Kif20b Kif20b Arid1a Arid1a Arhgap35 Arhgap35 Grhl3 Grhl3 Ptch1 Ptch1 Lias Lias Lmo4 Lmo4 Cited2 Cited2 Prkacb Prkacb Adm Adm Mks1 Mks1 Tsc1 Tsc1 Ptk7 Ptk7 Kdm2a Kdm2a Lrp2 Lrp2 Bmp4 Bmp4 Pax3 Pax3 Lrrc1 Lrrc1 Cdk20 Cdk20 Med12 Med12 Cluap1 Cluap1 Vangl2 Vangl2 Apaf1 Apaf1 Sfrp5 Sfrp5 Rock2 Rock2 Celsr1 Celsr1 Grhl2 Grhl2 Kat2a Kat2a Cecr2 Cecr2 Dlc1 Dlc1 Gm19410 Gm19410 Prickle1 Prickle1 Fzd2 Fzd2 Rara Rara Rab23 Rab23 Tulp3 Tulp3 Bcl10 Bcl10 Pfn1 Pfn1 Wnt5a Wnt5a Hectd1 Hectd1 Enah Enah Rala Rala Ift172 Ift172 Rgma Rgma Nckap1 Nckap1 Bbs4 Bbs4 Sufu Sufu ENSDORP00000023623 ENSDORP00000023623 Vasp Vasp Rps7 Rps7 Sdc4 Sdc4 Glmn Glmn Fzd3 Fzd3 Cthrc1 Cthrc1 Specc1l Specc1l Ski Ski Sfrp2 Sfrp2 Nog Nog ENSDORP00000026600 ENSDORP00000026600 ENSDORP00000027373 ENSDORP00000027373 Lhx2 Lhx2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Ift57Intraflagellar transport protein 57 homolog isoform X1. (429 aa)
Mthfd1lMonofunctional C1-tetrahydrofolate synthase, mitochondrial. (831 aa)
Kdm2bLysine-specific demethylase 2B isoform X2. (704 aa)
Tsc2Tuberin isoform X1. (1809 aa)
MthfrMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (559 aa)
Setd2Histone-lysine N-methyltransferase SETD2. (2320 aa)
Opa1LOW QUALITY PROTEIN: dynamin-like 120 kDa protein, mitochondrial; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (922 aa)
PrkacacAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
Mthfd1C-1-tetrahydrofolate synthase, cytoplasmic. (938 aa)
Deaf1Deformed epidermal autoregulatory factor 1 homolog. (500 aa)
Sema4csemaphorin-4C; Belongs to the semaphorin family. (831 aa)
Tgif1Homeobox protein TGIF1 isoform X1. (270 aa)
FuzProtein fuzzy homolog isoform X2. (415 aa)
Sfrp1Secreted frizzled-related protein 1. (314 aa)
Brd2Bromodomain-containing protein 2 isoform X1. (801 aa)
ScribProtein scribble homolog. (1608 aa)
Gatad2aTranscriptional repressor p66-alpha isoform X1. (623 aa)
Zeb2Zinc finger E-box-binding homeobox 2. (1249 aa)
RargRetinoic acid receptor gamma isoform X1. (458 aa)
Traf6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (529 aa)
Cc2d2aCoiled-coil and C2 domain-containing protein 2A. (1580 aa)
Abl2Tyrosine-protein kinase. (1132 aa)
Folr1Folate receptor alpha-like. (256 aa)
Tfap2aTranscription factor AP-2-alpha isoform X1. (437 aa)
TbxtBrachyury protein isoform X1. (137 aa)
Sall4Sal-like protein 4. (998 aa)
Plxnb2Plexin B2. (470 aa)
Trim71E3 ubiquitin-protein ligase TRIM71. (842 aa)
Ift122Intraflagellar transport protein 122 homolog isoform X2. (1242 aa)
Pax2Paired box protein Pax-2 isoform X2. (417 aa)
Fzd1Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (656 aa)
Fzd6Frizzled-6; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa)
Dvl2Segment polarity protein dishevelled homolog DVL-2 isoform X3. (736 aa)
Dvl3Segment polarity protein dishevelled homolog DVL-3. (716 aa)
StilSCL-interrupting locus protein. (1126 aa)
St14Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family. (855 aa)
Sall1Sal-like protein 1. (144 aa)
Tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (443 aa)
Tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (130 aa)
Phactr4Phosphatase and actin regulator. (701 aa)
Lrp6Low-density lipoprotein receptor-related protein 6. (1602 aa)
Sec24bLOW QUALITY PROTEIN: protein transport protein Sec24B. (1232 aa)
Tmed2Transmembrane emp24 domain-containing protein 2. (112 aa)
Kif20bKinesin-like protein KIF20B isoform X2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1771 aa)
Arid1aAT-rich interactive domain-containing protein 1A isoform X2. (1862 aa)
Arhgap35Rho GTPase-activating protein 35. (1500 aa)
Grhl3Grainyhead-like protein 3 homolog. (603 aa)
Ptch1Protein patched homolog 1. (1300 aa)
LiasLipoyl synthase, mitochondrial. (74 aa)
Lmo4LIM domain transcription factor LMO4. (165 aa)
Cited2Cbp/p300-interacting transactivator 2. (271 aa)
PrkacbcAMP-dependent protein kinase catalytic subunit beta isoform X2; Belongs to the protein kinase superfamily. (351 aa)
AdmADM. (189 aa)
Mks1Meckel syndrome type 1 protein. (559 aa)
Tsc1Hamartin isoform X1. (1121 aa)
Ptk7Inactive tyrosine-protein kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1043 aa)
Kdm2aLysine-specific demethylase 2A. (1112 aa)
Lrp2Low-density lipoprotein receptor-related protein 2. (4626 aa)
Bmp4Bone morphogenetic protein 4. (409 aa)
Pax3Paired box protein Pax-3 isoform X1. (484 aa)
Lrrc1Leucine-rich repeat-containing protein 1. (419 aa)
Cdk20Cyclin-dependent kinase 20; Belongs to the protein kinase superfamily. (346 aa)
Med12Mediator of RNA polymerase II transcription subunit 12. (2183 aa)
Cluap1Clusterin-associated protein 1 isoform X1. (413 aa)
Vangl2Vang-like protein. (550 aa)
Apaf1Apoptotic protease-activating factor 1. (1107 aa)
Sfrp5Secreted frizzled-related protein 5. (311 aa)
Rock2Rho-associated protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1114 aa)
Celsr1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2759 aa)
Grhl2Grainyhead-like protein 2 homolog. (631 aa)
Kat2aHistone acetyltransferase KAT2A isoform X1. (829 aa)
Cecr2Cat eye syndrome critical region protein 2 isoform X2. (1394 aa)
Dlc1Rho GTPase-activating protein 7 isoform X1. (1125 aa)
Gm19410Predicted gene, 19410. (2104 aa)
Prickle1Prickle-like protein 1. (838 aa)
Fzd2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
RaraRetinoic acid receptor alpha. (343 aa)
Rab23Ras-related protein Rab-23. (236 aa)
Tulp3Tubby-like protein; Belongs to the TUB family. (452 aa)
Bcl10B-cell lymphoma/leukemia 10. (117 aa)
Pfn1Profilin; Belongs to the profilin family. (140 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
Hectd1E3 ubiquitin-protein ligase HECTD1 isoform X1. (2610 aa)
EnahENAH actin regulator. (731 aa)
RalaRas-related protein Ral-A. (206 aa)
Ift172Intraflagellar transport protein 172 homolog. (1659 aa)
RgmaRepulsive guidance molecule A. (452 aa)
Nckap1Nck-associated protein 1. (1100 aa)
Bbs4Bardet-Biedl syndrome 4 protein isoform X2. (514 aa)
SufuSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (485 aa)
ENSDORP00000023623annotation not available (140 aa)
VaspVasodilator-stimulated phosphoprotein isoform X2; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (379 aa)
Rps740S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (169 aa)
Sdc4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (204 aa)
GlmnGlomulin. (595 aa)
Fzd3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
Cthrc1Collagen triple helix repeat-containing protein 1. (245 aa)
Specc1lcytospin-A. (1130 aa)
SkiSki oncogene. (719 aa)
Sfrp2Secreted frizzled-related protein 2. (296 aa)
NogNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (233 aa)
ENSDORP00000026600annotation not available (64 aa)
ENSDORP00000027373annotation not available (156 aa)
Lhx2LIM/homeobox protein Lhx2 isoform X1. (406 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.