STRINGSTRING
Krt27 Krt27 Lhx2 Lhx2 Hdac1 Hdac1 Inhba Inhba Psen2 Psen2 Lrp4 Lrp4 Bcl2 Bcl2 Lamc1 Lamc1 Sos1 Sos1 Fst Fst Pias4 Pias4 Pdgfa Pdgfa Tgfb2 Tgfb2 Gnas Gnas Runx1 Runx1 Ngfr Ngfr Smo Smo Fzd6 Fzd6 Wnt10a Wnt10a Dkk1 Dkk1 Dicer1 Dicer1 Lgr5 Lgr5 Rbpj Rbpj Krt25 Krt25 Krt28 Krt28 Celsr1 Celsr1 Intu Intu Fgf10 Fgf10 Ercc2 Ercc2 Gli2 Gli2 Edaradd Edaradd Igfbp5 Igfbp5 Vangl2 Vangl2 Ldb2 Ldb2 Tmem79 Tmem79 Pum2 Pum2 Nf1 Nf1 Dsg4 Dsg4 Trps1 Trps1 Rela Rela Egfr Egfr Hdac2 Hdac2 Alx4 Alx4 Zmpste24 Zmpste24 Cd109 Cd109 Foxn1 Foxn1 Tnfrsf19 Tnfrsf19 Edar Edar Nom1 Nom1 Pla2g10 Pla2g10 Krt71 Krt71 Lama5 Lama5 Hoxc13 Hoxc13 Apc Apc Fgfr2 Fgfr2 Fuz Fuz Tp63 Tp63 Fgf7 Fgf7 Zdhhc21 Zdhhc21 Trpc4ap Trpc4ap Atp7a Atp7a Nsdhl Nsdhl Tfap2c Tfap2c ENSDORP00000020585 ENSDORP00000020585 Runx3 Runx3 Acvr1b Acvr1b ENSDORP00000022774 ENSDORP00000022774 Apcdd1 Apcdd1 Eda Eda Ldb1 Ldb1 Sostdc1 Sostdc1 Fzd3 Fzd3 Lgr4 Lgr4 Dbi Dbi Nsun2 Nsun2 Snai1 Snai1 Sav1 Sav1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Krt27Keratin, type I cytoskeletal 27; Belongs to the intermediate filament family. (356 aa)
Lhx2LIM/homeobox protein Lhx2 isoform X1. (406 aa)
Hdac1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (477 aa)
InhbaInhibin beta A chain. (133 aa)
Psen2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (447 aa)
Lrp4Low-density lipoprotein receptor-related protein 4. (1882 aa)
Bcl2Apoptosis regulator Bcl-2. (196 aa)
Lamc1Laminin subunit gamma-1. (1563 aa)
Sos1Son of sevenless homolog 1. (1301 aa)
FstFollistatin isoform X1. (344 aa)
Pias4E3 SUMO-protein ligase PIAS4. (517 aa)
PdgfaPlatelet-derived growth factor subunit A isoform X1; Belongs to the PDGF/VEGF growth factor family. (210 aa)
Tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (443 aa)
GnasGuanine nucleotide-binding protein G(S) subunit alpha isoform X1. (394 aa)
Runx1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (468 aa)
NgfrTumor necrosis factor receptor superfamily member 16. (409 aa)
SmoSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (788 aa)
Fzd6Frizzled-6; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa)
Wnt10aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
Dkk1Dickkopf-related protein 1. (268 aa)
Dicer1Endoribonuclease Dicer isoform X1; Belongs to the helicase family. Dicer subfamily. (1912 aa)
Lgr5Leucine-rich repeat-containing G-protein coupled receptor 5 isoform X1. (907 aa)
RbpjRecombining binding protein suppressor of hairless isoform X1. (526 aa)
Krt25Keratin, type I cytoskeletal 25; Belongs to the intermediate filament family. (451 aa)
Krt28Keratin, type I cytoskeletal 28 isoform X1; Belongs to the intermediate filament family. (457 aa)
Celsr1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2759 aa)
IntuProtein inturned. (853 aa)
Fgf10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (223 aa)
Ercc2TFIIH basal transcription factor complex helicase XPD subunit isoform X1. (764 aa)
Gli2Zinc finger protein GLI2. (1549 aa)
Edaraddectodysplasin-A receptor-associated adapter protein. (194 aa)
Igfbp5Insulin-like growth factor-binding protein 5. (271 aa)
Vangl2Vang-like protein. (550 aa)
Ldb2LIM domain binding 2. (308 aa)
Tmem79Transmembrane protein 79. (395 aa)
Pum2Pumilio homolog 2. (1029 aa)
Nf1Neurofibromin isoform X1. (2841 aa)
Dsg4LOW QUALITY PROTEIN: desmoglein-4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1038 aa)
Trps1Zinc finger transcription factor Trps1 isoform X1. (1284 aa)
RelaTranscription factor p65 isoform X1. (236 aa)
EgfrReceptor protein-tyrosine kinase. (1215 aa)
Hdac2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa)
Alx4Homeobox protein aristaless-like 4. (411 aa)
Zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
Cd109CD109 antigen. (1420 aa)
Foxn1Forkhead box protein N1 isoform X2. (647 aa)
Tnfrsf19Tumor necrosis factor receptor superfamily member 19. (415 aa)
EdarTumor necrosis factor receptor superfamily member EDAR. (448 aa)
Nom1Nucleolar MIF4G domain-containing protein 1. (641 aa)
Pla2g10Phospholipase A(2). (149 aa)
Krt71Keratin, type II cytoskeletal 71; Belongs to the intermediate filament family. (528 aa)
Lama5Laminin subunit alpha-5. (3481 aa)
Hoxc13Homeobox protein Hox-C13. (322 aa)
ApcAdenomatous polyposis coli protein isoform X2. (2842 aa)
Fgfr2Fibroblast growth factor receptor. (819 aa)
FuzProtein fuzzy homolog isoform X2. (415 aa)
Tp63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
Fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
Zdhhc21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
Trpc4apShort transient receptor potential channel 4-associated protein. (742 aa)
Atp7aCopper-transporting ATPase 1. (1488 aa)
NsdhlSterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; Belongs to the 3-beta-HSD family. (361 aa)
Tfap2cTranscription factor AP-2 gamma. (471 aa)
ENSDORP00000020585annotation not available (80 aa)
Runx3Runt-related transcription factor 3. (337 aa)
Acvr1bReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (450 aa)
ENSDORP00000022774annotation not available (389 aa)
Apcdd1Protein APCDD1. (510 aa)
Edaectodysplasin-A isoform X1; Belongs to the tumor necrosis factor family. (390 aa)
Ldb1LIM domain-binding protein 1 isoform X1. (411 aa)
Sostdc1Sclerostin domain-containing protein 1. (206 aa)
Fzd3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
Lgr4LOW QUALITY PROTEIN: leucine-rich repeat-containing G-protein coupled receptor 4. (943 aa)
Dbiacyl-CoA-binding protein. (79 aa)
Nsun2tRNA (Cytosine(34)-C(5))-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (736 aa)
Snai1Zinc finger protein SNAI1. (240 aa)
Sav1Protein salvador homolog 1. (384 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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