27 items (Dipodomys ordii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Pdpk1	3-phosphoinositide-dependent protein kinase 1 isoform X1. (552 aa)
	Igf1	Insulin-like growth factor I isoform X2. (130 aa)
	Lmbrd1	Probable lysosomal cobalamin transporter. (527 aa)
	Snx1	Sorting nexin-1. (304 aa)
	Brwd3	Bromodomain and WD repeat-containing protein 3. (1800 aa)
	Shc1	SHC-transforming protein 1 isoform X2. (473 aa)
	Slc2a2	Solute carrier family 2, facilitated glucose transporter member 2 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (521 aa)
	Igf1r	Tyrosine-protein kinase receptor. (923 aa)
	Ptprf	Receptor-type tyrosine-protein phosphatase F isoform X1. (1901 aa)
	Ptpn11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (583 aa)
	Enpp1	Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (908 aa)
	Ccdc88a	Girdin. (1835 aa)
	Elp6	Elongator complex protein 6 isoform X1. (263 aa)
	Plcg1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
	Irs1	Insulin receptor substrate 1. (1239 aa)
	Irs4	Insulin receptor substrate 4. (1262 aa)
	Phip	PH-interacting protein isoform X1. (1758 aa)
	Snx2	Sorting nexin-2. (506 aa)
	Grb10	Growth factor receptor-bound protein 10 isoform X2. (541 aa)
	ENSDORP00000019661	annotation not available (110 aa)
	Pik3r1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
	Snx4	Sorting nexin 4. (392 aa)
	Igf2	Insulin-like growth factor II. (176 aa)
	Brwd1	Bromodomain and WD repeat-containing protein 1. (572 aa)
	Insr	Tyrosine-protein kinase receptor. (1183 aa)
	Ptpn1	Tyrosine-protein phosphatase non-receptor type. (436 aa)
	Sorbs1	Sorbin and SH3 domain containing 1. (1290 aa)

Your Current Organism:

Dipodomys ordii

NCBI taxonomy Id: 10020
Other names: D. ordii

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Brwd1	Phip	ENSDORP00000021528	ENSDORP00000011981	Bromodomain and WD repeat-containing protein 1.	PH-interacting protein isoform X1.	0.441
Brwd3	Phip	ENSDORP00000003106	ENSDORP00000011981	Bromodomain and WD repeat-containing protein 3.	PH-interacting protein isoform X1.	0.441
ENSDORP00000019661	Phip	ENSDORP00000019661	ENSDORP00000011981	annotation not available	PH-interacting protein isoform X1.	0.434
Grb10	Igf1r	ENSDORP00000014594	ENSDORP00000004240	Growth factor receptor-bound protein 10 isoform X2.	Tyrosine-protein kinase receptor.	0.981
Grb10	Igf2	ENSDORP00000014594	ENSDORP00000020877	Growth factor receptor-bound protein 10 isoform X2.	Insulin-like growth factor II.	0.545
Grb10	Insr	ENSDORP00000014594	ENSDORP00000024273	Growth factor receptor-bound protein 10 isoform X2.	Tyrosine-protein kinase receptor.	0.964
Grb10	Irs1	ENSDORP00000014594	ENSDORP00000011617	Growth factor receptor-bound protein 10 isoform X2.	Insulin receptor substrate 1.	0.697
Grb10	Irs4	ENSDORP00000014594	ENSDORP00000011859	Growth factor receptor-bound protein 10 isoform X2.	Insulin receptor substrate 4.	0.648
Grb10	Pdpk1	ENSDORP00000014594	ENSDORP00000011222	Growth factor receptor-bound protein 10 isoform X2.	3-phosphoinositide-dependent protein kinase 1 isoform X1.	0.468
Grb10	Pik3r1	ENSDORP00000014594	ENSDORP00000020150	Growth factor receptor-bound protein 10 isoform X2.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.814
Grb10	Plcg1	ENSDORP00000014594	ENSDORP00000011410	Growth factor receptor-bound protein 10 isoform X2.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.548
Grb10	Ptpn1	ENSDORP00000014594	ENSDORP00000024749	Growth factor receptor-bound protein 10 isoform X2.	Tyrosine-protein phosphatase non-receptor type.	0.614
Grb10	Ptpn11	ENSDORP00000014594	ENSDORP00000007760	Growth factor receptor-bound protein 10 isoform X2.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.606
Grb10	Ptprf	ENSDORP00000014594	ENSDORP00000005537	Growth factor receptor-bound protein 10 isoform X2.	Receptor-type tyrosine-protein phosphatase F isoform X1.	0.587
Grb10	Shc1	ENSDORP00000014594	ENSDORP00000003514	Growth factor receptor-bound protein 10 isoform X2.	SHC-transforming protein 1 isoform X2.	0.579
Igf1	Igf1r	ENSDORP00000000221	ENSDORP00000004240	Insulin-like growth factor I isoform X2.	Tyrosine-protein kinase receptor.	0.782
Igf1	Insr	ENSDORP00000000221	ENSDORP00000024273	Insulin-like growth factor I isoform X2.	Tyrosine-protein kinase receptor.	0.782
Igf1r	Grb10	ENSDORP00000004240	ENSDORP00000014594	Tyrosine-protein kinase receptor.	Growth factor receptor-bound protein 10 isoform X2.	0.981
Igf1r	Igf1	ENSDORP00000004240	ENSDORP00000000221	Tyrosine-protein kinase receptor.	Insulin-like growth factor I isoform X2.	0.782
Igf1r	Igf2	ENSDORP00000004240	ENSDORP00000020877	Tyrosine-protein kinase receptor.	Insulin-like growth factor II.	0.992