6 items (Dipodomys ordii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Plcg1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
	Pik3r1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
	Grb2	Growth factor receptor-bound protein 2. (217 aa)
	Ngfr	Tumor necrosis factor receptor superfamily member 16. (409 aa)
	Shc1	SHC-transforming protein 1 isoform X2. (473 aa)
	Frs2	Fibroblast growth factor receptor substrate 2. (507 aa)

Your Current Organism:

Dipodomys ordii

NCBI taxonomy Id: 10020
Other names: D. ordii

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Frs2	Grb2	ENSDORP00000018239	ENSDORP00000027785	Fibroblast growth factor receptor substrate 2.	Growth factor receptor-bound protein 2.	0.993
Frs2	Pik3r1	ENSDORP00000018239	ENSDORP00000020150	Fibroblast growth factor receptor substrate 2.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.665
Frs2	Shc1	ENSDORP00000018239	ENSDORP00000003514	Fibroblast growth factor receptor substrate 2.	SHC-transforming protein 1 isoform X2.	0.619
Grb2	Frs2	ENSDORP00000027785	ENSDORP00000018239	Growth factor receptor-bound protein 2.	Fibroblast growth factor receptor substrate 2.	0.993
Grb2	Ngfr	ENSDORP00000027785	ENSDORP00000004169	Growth factor receptor-bound protein 2.	Tumor necrosis factor receptor superfamily member 16.	0.889
Grb2	Pik3r1	ENSDORP00000027785	ENSDORP00000020150	Growth factor receptor-bound protein 2.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.985
Grb2	Plcg1	ENSDORP00000027785	ENSDORP00000011410	Growth factor receptor-bound protein 2.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.983
Grb2	Shc1	ENSDORP00000027785	ENSDORP00000003514	Growth factor receptor-bound protein 2.	SHC-transforming protein 1 isoform X2.	0.999
Ngfr	Grb2	ENSDORP00000004169	ENSDORP00000027785	Tumor necrosis factor receptor superfamily member 16.	Growth factor receptor-bound protein 2.	0.889
Ngfr	Shc1	ENSDORP00000004169	ENSDORP00000003514	Tumor necrosis factor receptor superfamily member 16.	SHC-transforming protein 1 isoform X2.	0.885
Pik3r1	Frs2	ENSDORP00000020150	ENSDORP00000018239	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	Fibroblast growth factor receptor substrate 2.	0.665
Pik3r1	Grb2	ENSDORP00000020150	ENSDORP00000027785	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	Growth factor receptor-bound protein 2.	0.985
Pik3r1	Plcg1	ENSDORP00000020150	ENSDORP00000011410	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.914
Pik3r1	Shc1	ENSDORP00000020150	ENSDORP00000003514	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	SHC-transforming protein 1 isoform X2.	0.953
Plcg1	Grb2	ENSDORP00000011410	ENSDORP00000027785	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Growth factor receptor-bound protein 2.	0.983
Plcg1	Pik3r1	ENSDORP00000011410	ENSDORP00000020150	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.914
Plcg1	Shc1	ENSDORP00000011410	ENSDORP00000003514	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	SHC-transforming protein 1 isoform X2.	0.786
Shc1	Frs2	ENSDORP00000003514	ENSDORP00000018239	SHC-transforming protein 1 isoform X2.	Fibroblast growth factor receptor substrate 2.	0.619
Shc1	Grb2	ENSDORP00000003514	ENSDORP00000027785	SHC-transforming protein 1 isoform X2.	Growth factor receptor-bound protein 2.	0.999
Shc1	Ngfr	ENSDORP00000003514	ENSDORP00000004169	SHC-transforming protein 1 isoform X2.	Tumor necrosis factor receptor superfamily member 16.	0.885