STRINGSTRING
Mtor Mtor Meis2 Meis2 Glp1r Glp1r Nrxn3 Nrxn3 Ctns Ctns Ppp1r1b Ppp1r1b Adgrb3 Adgrb3 Synj1 Synj1 Aaas Aaas Kalrn Kalrn Slc24a2 Slc24a2 Mapk8ip2 Mapk8ip2 Dbh Dbh Deaf1 Deaf1 Tnr Tnr Rapgef3 Rapgef3 Ythdf1 Ythdf1 Stra6 Stra6 Nrgn Nrgn Gabrb3 Gabrb3 Ift20 Ift20 Vdac3 Vdac3 Pde1b Pde1b Ndrg4 Ndrg4 Cacna1e Cacna1e Actr2 Actr2 Ap1s2 Ap1s2 Eif2ak4 Eif2ak4 Abca7 Abca7 Srf Srf Vdac1 Vdac1 Epm2a Epm2a Nts Nts Agt Agt Ckap5 Ckap5 Nf1 Nf1 Grin2a Grin2a Map1a Map1a Shank2 Shank2 Csmd1 Csmd1 Ric8a Ric8a Ephb2 Ephb2 Uba6 Uba6 Tsc1 Tsc1 Abl2 Abl2 Creb1 Creb1 Elavl4 Elavl4 Dcdc2a Dcdc2a Nps Nps Taco1 Taco1 Slc6a1 Slc6a1 Nrxn2 Nrxn2 Pgrmc1 Pgrmc1 Rgs14 Rgs14 Shank1 Shank1 Ppt1 Ppt1 Htt Htt Pak1 Pak1 Reln Reln Sorcs3 Sorcs3 Npas4 Npas4 Arc Arc Braf Braf ENSDORP00000012692 ENSDORP00000012692 Drd2 Drd2 Zzef1 Zzef1 Crh Crh Tbr1 Tbr1 Chrd Chrd Th Th Ucn Ucn Slc8a2 Slc8a2 Fosl1 Fosl1 Abcc8 Abcc8 Lgmn Lgmn Jph4 Jph4 Slc7a11 Slc7a11 Atp1a2 Atp1a2 Itgb1 Itgb1 Adcy3 Adcy3 Rin1 Rin1 Htr6 Htr6 Csmd2 Csmd2 Ntrk2 Ntrk2 Kit Kit Nlgn3 Nlgn3 Ttc36 Ttc36 Kmt2a Kmt2a Ddhd2 Ddhd2 Foxp2 Foxp2 Cdk5 Cdk5 Dgki Dgki Ptn Ptn Pde8b Pde8b Dkk1 Dkk1 B4galt2 B4galt2 Hmgcr Hmgcr Synpo Synpo Git1 Git1 Drd5 Drd5 Nptn Nptn Atad1 Atad1 Hif1a Hif1a Ube3a Ube3a Lrrn4 Lrrn4 Idua Idua Comt Comt En1 En1 Ptrhd1 Ptrhd1 Drd1 Drd1 Amph Amph Syt11 Syt11 Nrxn1 Nrxn1 Sgk1 Sgk1 Syngap1 Syngap1 Tpbg Tpbg Neurod2 Neurod2 Cln8 Cln8 Chrnb2 Chrnb2 Tanc1 Tanc1 Arf4 Arf4 Crhr1 Crhr1 Cacna1c Cacna1c Btg2 Btg2 Plcb1 Plcb1 Drd3 Drd3 Slc1a1 Slc1a1 Nptx2 Nptx2 Grm7 Grm7 Cntn2 Cntn2 Chst10 Chst10 Prkar2b Prkar2b Foxb1 Foxb1 Slc8a3 Slc8a3 Grin1 Grin1 Bche Bche Shank3 Shank3 Fgf13 Fgf13 Pak6 Pak6 Cic Cic Ptgs1 Ptgs1 Rag1 Rag1 Atxn1 Atxn1 App App Atxn1l Atxn1l Mecp2 Mecp2 Nog Nog Snap25 Snap25 LOC106002855 LOC106002855 Atp8a1 Atp8a1 ENSDORP00000026600 ENSDORP00000026600 Chrna7 Chrna7 Gmfb Gmfb Specc1 Specc1 Gabra5 Gabra5 Tafa2 Tafa2 ENSDORP00000027710 ENSDORP00000027710 Cln3 Cln3 Asic1 Asic1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MtorSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2457 aa)
Meis2Homeobox protein Meis2. (438 aa)
Glp1rGlucagon-like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (331 aa)
Nrxn3Neurexin 3 isoform X2. (1571 aa)
CtnsCystinosin isoform X2. (353 aa)
Ppp1r1bProtein phosphatase 1 regulatory subunit 1B. (192 aa)
Adgrb3Brain-specific angiogenesis inhibitor 3; Belongs to the G-protein coupled receptor 2 family. (655 aa)
Synj1Synaptojanin-1 isoform X2. (693 aa)
AaasAladin. (555 aa)
KalrnKalirin isoform X2. (2981 aa)
Slc24a2Sodium/potassium/calcium exchanger 2 isoform X1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (665 aa)
Mapk8ip2C-Jun-amino-terminal kinase-interacting protein 2. (804 aa)
DbhDopamine beta-hydroxylase. (620 aa)
Deaf1Deformed epidermal autoregulatory factor 1 homolog. (500 aa)
Tnrtenascin-R. (1361 aa)
Rapgef3Rap guanine nucleotide exchange factor 3. (216 aa)
Ythdf1YTH domain-containing family protein 1. (573 aa)
Stra6Stimulated by retinoic acid gene 6 protein homolog. (670 aa)
NrgnNeurogranin. (78 aa)
Gabrb3Gamma-aminobutyric acid receptor subunit beta-3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (495 aa)
Ift20Intraflagellar transport protein 20 homolog isoform X1. (132 aa)
Vdac3Voltage-dependent anion-selective channel protein 3. (283 aa)
Pde1bPhosphodiesterase. (535 aa)
Ndrg4Protein NDRG4 isoform X1. (404 aa)
Cacna1eVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2325 aa)
Actr2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (394 aa)
Ap1s2AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (157 aa)
Eif2ak4Eukaryotic translation initiation factor 2-alpha kinase 4. (1599 aa)
Abca7ATP-binding cassette sub-family A member 7. (1849 aa)
SrfSerum response factor. (508 aa)
Vdac1Voltage-dependent anion-selective channel protein 1. (296 aa)
Epm2aLaforin. (230 aa)
NtsNeurotensin/neuromedin N. (170 aa)
AgtAngiotensinogen; Belongs to the serpin family. (473 aa)
Ckap5Cytoskeleton-associated protein 5. (2000 aa)
Nf1Neurofibromin isoform X1. (2841 aa)
Grin2aGlutamate receptor ionotropic, NMDA 2A. (1301 aa)
Map1aMicrotubule-associated protein 1A. (2699 aa)
Shank2SH3 and multiple ankyrin repeat domains protein 2 isoform X1. (1832 aa)
Csmd1CUB and sushi domain-containing protein 1-like. (3265 aa)
Ric8asynembryn-A. (494 aa)
Ephb2Ephrin type-B receptor 2 isoform X2. (1018 aa)
Uba6Ubiquitin-like modifier-activating enzyme 6. (1045 aa)
Tsc1Hamartin isoform X1. (1121 aa)
Abl2Tyrosine-protein kinase. (1132 aa)
Creb1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
Elavl4ELAV-like protein; Belongs to the RRM elav family. (386 aa)
Dcdc2aDoublecortin domain-containing protein 2. (446 aa)
NpsNeuropeptide S. (89 aa)
Taco1Translational activator of cytochrome c oxidase 1. (294 aa)
Slc6a1Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (599 aa)
Nrxn2Neurexin-2-beta isoform X1. (1400 aa)
Pgrmc1Membrane-associated progesterone receptor component 1; Belongs to the cytochrome b5 family. (194 aa)
Rgs14Regulator of G-protein signaling 14. (551 aa)
Shank1SH3 and multiple ankyrin repeat domains protein 1. (1300 aa)
Ppt1Palmitoyl-protein thioesterase 1. (200 aa)
HttHuntingtin. (3048 aa)
Pak1Non-specific serine/threonine protein kinase. (544 aa)
RelnReelin. (3415 aa)
Sorcs3VPS10 domain-containing receptor SorCS3. (1148 aa)
Npas4Neuronal PAS domain-containing protein 4. (802 aa)
ArcActivity-regulated cytoskeleton-associated protein. (396 aa)
BrafSerine/threonine-protein kinase B-raf. (705 aa)
ENSDORP00000012692annotation not available (98 aa)
Drd2D(2) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (443 aa)
Zzef1LOW QUALITY PROTEIN: zinc finger ZZ-type and EF-hand domain-containing protein 1. (2561 aa)
CrhCorticoliberin. (188 aa)
Tbr1T-box brain protein 1. (682 aa)
ChrdChordin isoform X1. (944 aa)
ThTyrosine 3-monooxygenase isoform X1. (519 aa)
UcnUrocortin. (130 aa)
Slc8a2Sodium/calcium exchanger 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (776 aa)
Fosl1Fos-related antigen 1 isoform X1. (278 aa)
Abcc8ATP-binding cassette sub-family C member 8 isoform X1. (1582 aa)
LgmnLegumain. (436 aa)
Jph4Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (628 aa)
Slc7a11Cystine/glutamate transporter. (503 aa)
Atp1a2Sodium/potassium-transporting ATPase subunit alpha. (1046 aa)
Itgb1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
Adcy3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
Rin1Ras and Rab interactor 1. (785 aa)
Htr65-hydroxytryptamine receptor 6; Belongs to the G-protein coupled receptor 1 family. (438 aa)
Csmd2CUB and sushi domain-containing protein 2. (3483 aa)
Ntrk2Tyrosine-protein kinase receptor. (821 aa)
KitMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa)
Nlgn3Neuroligin-3 isoform X1. (848 aa)
Ttc36Tetratricopeptide repeat protein 36 isoform X1. (188 aa)
Kmt2aHistone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (3886 aa)
Ddhd2Phospholipase DDHD2. (161 aa)
Foxp2Forkhead box protein P2 isoform X1. (736 aa)
Cdk5Cyclin-dependent-like kinase 5 isoform X1; Belongs to the protein kinase superfamily. (292 aa)
DgkiDiacylglycerol kinase. (901 aa)
PtnPleiotrophin. (136 aa)
Pde8bPhosphodiesterase. (783 aa)
Dkk1Dickkopf-related protein 1. (268 aa)
B4galt2Beta-1,4-galactosyltransferase 2. (369 aa)
Hmgcr3-hydroxy-3-methylglutaryl coenzyme A reductase. (404 aa)
SynpoSynaptopodin isoform X1. (926 aa)
Git1ARF GTPase-activating protein GIT1. (758 aa)
Drd5D(1B) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (428 aa)
NptnNeuroplastin. (397 aa)
Atad1ATPase family AAA domain-containing protein 1; Belongs to the AAA ATPase family. (348 aa)
Hif1aHypoxia-inducible factor 1-alpha. (246 aa)
Ube3aUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (873 aa)
Lrrn4Leucine-rich repeat neuronal protein 4. (732 aa)
Iduaalpha-L-iduronidase. (592 aa)
ComtCatechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. (267 aa)
En1Homeobox protein engrailed-like. (140 aa)
Ptrhd1Putative peptidyl-tRNA hydrolase PTRHD1. (146 aa)
Drd1D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (447 aa)
AmphAmphiphysin. (639 aa)
Syt11Synaptotagmin-11. (431 aa)
Nrxn1Neurexin-1-beta isoform X1. (1515 aa)
Sgk1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (445 aa)
Syngap1ras/Rap GTPase-activating protein SynGAP. (1343 aa)
TpbgTrophoblast glycoprotein. (336 aa)
Neurod2Neurogenic differentiation factor. (383 aa)
Cln8Protein CLN8. (288 aa)
Chrnb2Neuronal acetylcholine receptor subunit beta-2 isoform X1. (504 aa)
Tanc1Protein TANC1. (1859 aa)
Arf4ADP-ribosylation factor 4; Belongs to the small GTPase superfamily. Arf family. (180 aa)
Crhr1Corticotropin-releasing factor receptor 1 isoform X1; Belongs to the G-protein coupled receptor 2 family. (415 aa)
Cacna1cVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1179 aa)
Btg2Protein BTG2. (158 aa)
Plcb11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
Drd3D(3) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (445 aa)
Slc1a1Amino acid transporter. (531 aa)
Nptx2Neuronal pentraxin-2. (397 aa)
Grm7Metabotropic glutamate receptor 7 isoform X1. (918 aa)
Cntn2Contactin-2. (1044 aa)
Chst10Carbohydrate sulfotransferase. (374 aa)
Prkar2bcAMP-dependent protein kinase type II-beta regulatory subunit. (258 aa)
Foxb1Forkhead box protein B1. (325 aa)
Slc8a3Sodium/calcium exchanger 3 isoform X1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (926 aa)
Grin1LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 1. (926 aa)
BcheCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (63 aa)
Shank3SH3 and multiple ankyrin repeat domains protein 3. (1417 aa)
Fgf13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (245 aa)
Pak6Non-specific serine/threonine protein kinase. (668 aa)
CicProtein capicua homolog isoform X1. (2470 aa)
Ptgs1Prostaglandin G/H synthase 1. (600 aa)
Rag1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa)
Atxn1Ataxin-1. (801 aa)
AppAmyloid beta A4 protein isoform X1. (770 aa)
Atxn1lAtaxin-1-like. (689 aa)
Mecp2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (500 aa)
NogNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (233 aa)
Snap25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
LOC106002855Neurexin-2-beta. (330 aa)
Atp8a1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1164 aa)
ENSDORP00000026600annotation not available (64 aa)
Chrna7Neuronal acetylcholine receptor subunit alpha-7. (568 aa)
GmfbGlia maturation factor; Belongs to the actin-binding proteins ADF family. GMF subfamily. (142 aa)
Specc1cytospin-B isoform X4. (636 aa)
Gabra5Gamma-aminobutyric acid receptor subunit alpha-5; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (463 aa)
Tafa2Protein FAM19A2. (131 aa)
ENSDORP00000027710annotation not available (102 aa)
Cln3Battenin. (437 aa)
Asic1Acid-sensing ion channel 1 isoform X3; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (526 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
Server load: low (12%) [HD]