STRINGSTRING
Tgfbr1 Tgfbr1 Erlin1 Erlin1 Fzd8 Fzd8 Syt11 Syt11 LOC105998252 LOC105998252 Trim28 Trim28 Grik2 Grik2 Pink1 Pink1 Smad2 Smad2 Gon7 Gon7 Ubox5 Ubox5 Ube2a Ube2a Usp13 Usp13 Ralb Ralb Ikbke Ikbke H13 H13 Vcl Vcl Nfkbia Nfkbia Hspbp1 Hspbp1 Wfs1 Wfs1 Rela Rela Rpl11 Rpl11 Usp7 Usp7 Nkd2 Nkd2 Lrpprc Lrpprc LOC106002211 LOC106002211 Ube2n Ube2n Scn5a Scn5a Bok Bok Atf6 Atf6 Wbp1l Wbp1l ENSDORP00000016922 ENSDORP00000016922 Fzd5 Fzd5 Blzf1 Blzf1 Cxcr4 Cxcr4 Bag6 Bag6 Tollip Tollip Elob Elob Prkar1a Prkar1a Abi2 Abi2 Apbb1 Apbb1 Ubash3a Ubash3a Apc Apc ENSDORP00000016209 ENSDORP00000016209 Usp9x Usp9x Spopl Spopl Traf6 Traf6 Derl1 Derl1 Ppargc1a Ppargc1a Slc25a5 Slc25a5 Traf1 Traf1 Hltf Hltf Rraga Rraga Stx8 Stx8 Pacrgl Pacrgl Foxo1 Foxo1 Cd40 Cd40 Faf1 Faf1 Psmd1 Psmd1 Per3 Per3 Tank Tank Fbxw9 Fbxw9 Prkaca Prkaca Rbx1 Rbx1 Bag5 Bag5 Sqstm1 Sqstm1 Cacul1 Cacul1 LOC105997812 LOC105997812 Nedd8 Nedd8 ENSDORP00000027934 ENSDORP00000027934 Ube2l3 Ube2l3 Egr2 Egr2 Ikbkg Ikbkg Ddx58 Ddx58 Scamp3 Scamp3 Ankra2 Ankra2 Rangap1 Rangap1 Pias2 Pias2 Nek6 Nek6 Vcp Vcp Ube2k Ube2k LOC106001046 LOC106001046 Smad7 Smad7 Bag4 Bag4 Ube2j1 Ube2j1 Trim37 Trim37 Ambra1 Ambra1 Rad18 Rad18 Polr2a Polr2a Ski Ski Ube2k-2 Ube2k-2 Myc Myc Slc22a18 Slc22a18 Pacrg Pacrg ENSDORP00000025450 ENSDORP00000025450 Prr5l Prr5l Sumo1 Sumo1 Egfr Egfr Nae1 Nae1 Sh3kbp1 Sh3kbp1 Laptm4b Laptm4b ENSDORP00000024671 ENSDORP00000024671 Ube2j2 Ube2j2 Tubb Tubb Glmn Glmn Smad6 Smad6 Mul1 Mul1 ENSDORP00000024097 ENSDORP00000024097 Rtn2 Rtn2 Usp2 Usp2 ENSDORP00000023736 ENSDORP00000023736 Myod1 Myod1 Trp53 Trp53 Caml Caml Arih1 Arih1 Atp6v0c Atp6v0c Uchl1 Uchl1 Gsk3b Gsk3b Smad3 Smad3 ENSDORP00000023166 ENSDORP00000023166 Rala Rala Calr Calr Fzd4 Fzd4 Ubb Ubb Traf5 Traf5 LOC105986631 LOC105986631 ENSDORP00000022369 ENSDORP00000022369 ENSDORP00000022365 ENSDORP00000022365 Gabarapl1 Gabarapl1 Crk Crk Prkar2b Prkar2b Arrb2 Arrb2 ENSDORP00000022159 ENSDORP00000022159 Uba52 Uba52 Yod1 Yod1 Rnf8 Rnf8 Bcl10 Bcl10 Patz1 Patz1 ENSDORP00000021689 ENSDORP00000021689 Psma3-2 Psma3-2 Per1 Per1 Fbxw7 Fbxw7 Axin2 Axin2 Mfhas1 Mfhas1 Ube2t Ube2t Spart Spart Pax6 Pax6 LOC105993014 LOC105993014 Eif4e2 Eif4e2 Tcp1 Tcp1 Aicda Aicda ENSDORP00000020658 ENSDORP00000020658 Fam178b Fam178b Mc4r Mc4r Trib2 Trib2 Ube2d1 Ube2d1 Axin1 Axin1 Pik3r1 Pik3r1 Erlin2 Erlin2 ENSDORP00000020034 ENSDORP00000020034 LOC105992166 LOC105992166 Ywhae Ywhae Prkacb Prkacb Brca1 Brca1 Arrb1 Arrb1 ENSDORP00000019733 ENSDORP00000019733 Washc1 Washc1 Gabarap Gabarap Ube2g1 Ube2g1 Hspa1b Hspa1b Rb1 Rb1 Gabarapl2 Gabarapl2 Cacybp Cacybp Becn1 Becn1 LOC105999841 LOC105999841 Ubxn7 Ubxn7 ENSDORP00000018748 ENSDORP00000018748 Trib1 Trib1 Tnk2 Tnk2 Ccdc50 Ccdc50 Sncaip Sncaip Txnip Txnip Dlg3 Dlg3 Laptm4a Laptm4a Cul4b Cul4b Rnf20 Rnf20 Tcp1-2 Tcp1-2 Dnm1l Dnm1l Xrcc5 Xrcc5 Otub1 Otub1 Kdm4a Kdm4a Ywhaz Ywhaz Ubash3b Ubash3b Hspd1 Hspd1 Hsp90ab1 Hsp90ab1 Smc6 Smc6 Flt3 Flt3 Triobp Triobp Ripk1 Ripk1 Smg5 Smg5 Nploc4 Nploc4 Usp25 Usp25 Nlk Nlk Clu Clu Ptk2b Ptk2b Cul4a Cul4a Rnf40 Rnf40 Gpi Gpi Pou5f1 Pou5f1 Anapc2 Anapc2 Ubxn1 Ubxn1 Rnf31 Rnf31 Rffl Rffl Jak1 Jak1 Arrdc5 Arrdc5 Aup1 Aup1 Traf3 Traf3 Tsg101 Tsg101 Daxx Daxx Map1lc3b Map1lc3b Isg15 Isg15 Pml Pml Chek2 Chek2 Hspa9 Hspa9 Herc2 Herc2 Faf2 Faf2 Aurka Aurka Wrap53 Wrap53 Bag2 Bag2 Cul5 Cul5 Arrdc1 Arrdc1 Fancl Fancl Fhit Fhit Usp19 Usp19 Snx9 Snx9 Atxn3 Atxn3 Rnf34 Rnf34 Stub1 Stub1 Zfp746 Zfp746 Rps27a Rps27a Rpl5 Rpl5 Hsp90aa1 Hsp90aa1 Cul3 Cul3 Fzd6 Fzd6 Gpr37 Gpr37 Prkar2a Prkar2a Slf1 Slf1 Smad5 Smad5 Slf2 Slf2 Ngfr Ngfr Rtn3 Rtn3 Hif1a Hif1a Jkamp Jkamp Prdx6 Prdx6 Traf2 Traf2 Kcnq3 Kcnq3 Bid Bid Shprh Shprh Rpa2 Rpa2 Rtn4 Rtn4 Det1 Det1 Pdlim2 Pdlim2 Cul9 Cul9 Pias4 Pias4 Pias1 Pias1 Ube2b Ube2b Asb4 Asb4 Sipa1l1 Sipa1l1 Cbs Cbs Syk Syk Cul1 Cul1 Kcnh2 Kcnh2 Lyn Lyn Cul2 Cul2 Traf4 Traf4 Erbb3 Erbb3 Pa2g4 Pa2g4 Tmbim6 Tmbim6 Rpl23 Rpl23 Pcbp2 Pcbp2 Ube2l6 Ube2l6 Spop Spop Ndufs2 Ndufs2 Bcl2 Bcl2 Ubc Ubc Trib3 Trib3 Psma3 Psma3 Fate1 Fate1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Tgfbr1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (490 aa)
Erlin1Erlin-1. (348 aa)
Fzd8Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (418 aa)
Syt11Synaptotagmin-11. (431 aa)
LOC105998252Transcription elongation factor B polypeptide 2 pseudogene. (103 aa)
Trim28Transcription intermediary factor 1-beta. (834 aa)
Grik2Glutamate receptor ionotropic, kainate 2 isoform X1. (908 aa)
Pink1Serine/threonine-protein kinase PINK1, mitochondrial. (577 aa)
Smad2Mothers against decapentaplegic homolog. (467 aa)
Gon7Uncharacterized protein C14orf142 homolog. (100 aa)
Ubox5RING finger protein 37 isoform X1. (541 aa)
Ube2aUbiquitin-conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
Usp13Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (863 aa)
RalbRas-related protein Ral-B. (206 aa)
IkbkeInhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1. (725 aa)
H13Minor histocompatibility antigen H13 isoform X1. (374 aa)
VclVinculin isoform X2. (1135 aa)
NfkbiaNF-kappa-B inhibitor alpha. (224 aa)
Hspbp1Hsp70-binding protein 1. (358 aa)
Wfs1Wolframin. (885 aa)
RelaTranscription factor p65 isoform X1. (236 aa)
Rpl1160S ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family. (178 aa)
Usp7Ubiquitin carboxyl-terminal hydrolase 7; Belongs to the peptidase C19 family. (891 aa)
Nkd2Protein naked cuticle homolog 2. (442 aa)
LrpprcLeucine-rich PPR motif-containing protein, mitochondrial. (1393 aa)
LOC106002211Small ubiquitin-related modifier. (89 aa)
Ube2nUbiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
Scn5aSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1926 aa)
BokBcl-2-related ovarian killer protein. (138 aa)
Atf6Cyclic AMP-dependent transcription factor ATF-6 alpha isoform X1. (663 aa)
Wbp1lWW domain binding protein 1-like isoform X1. (368 aa)
ENSDORP00000016922annotation not available (98 aa)
Fzd5Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
Blzf1Golgin-45. (405 aa)
Cxcr4C-X-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (357 aa)
Bag6Large proline-rich protein BAG6 isoform X5. (1127 aa)
TollipToll-interacting protein. (263 aa)
ElobTranscription elongation factor B polypeptide 2. (72 aa)
Prkar1acAMP-dependent protein kinase type I-alpha regulatory subunit. (381 aa)
Abi2Abl interactor 2 isoform X1. (446 aa)
Apbb1Amyloid beta A4 precursor protein-binding family B member 1 isoform X1. (708 aa)
Ubash3aUbiquitin-associated and SH3 domain-containing protein A isoform X2. (115 aa)
ApcAdenomatous polyposis coli protein isoform X2. (2842 aa)
ENSDORP00000016209annotation not available (179 aa)
Usp9xProbable ubiquitin carboxyl-terminal hydrolase FAF-X; Belongs to the peptidase C19 family. (2317 aa)
SpoplSpeckle-type POZ protein-like isoform X1. (392 aa)
Traf6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (529 aa)
Derl1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (213 aa)
Ppargc1aPeroxisome proliferator-activated receptor gamma coactivator 1-alpha. (797 aa)
Slc25a5ADP/ATP translocase 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
Traf1TNF receptor-associated factor. (408 aa)
HltfHelicase-like transcription factor isoform X5. (1004 aa)
RragaRas-related GTP-binding protein A. (313 aa)
Stx8Syntaxin-8. (126 aa)
PacrglPACRG-like protein. (248 aa)
Foxo1Forkhead box protein O1. (537 aa)
Cd40Tumor necrosis factor receptor superfamily member 5 isoform X1. (279 aa)
Faf1FAS-associated factor 1. (498 aa)
Psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (938 aa)
Per3Period circadian protein homolog 3 isoform X1. (1041 aa)
TankTRAF family member-associated NF-kappa-B activator isoform X2. (425 aa)
Fbxw9F-box/WD repeat-containing protein 9. (440 aa)
PrkacacAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
Rbx1E3 ubiquitin-protein ligase RBX1. (117 aa)
Bag5BAG family molecular chaperone regulator 5. (447 aa)
Sqstm1Sequestosome-1. (433 aa)
Cacul1CDK2-associated and cullin domain-containing protein 1; Belongs to the cullin family. (246 aa)
LOC105997812LOW QUALITY PROTEIN: uncharacterized protein LOC105997812. (91 aa)
Nedd8NEDD8. (81 aa)
ENSDORP00000027934annotation not available (118 aa)
Ube2l3Ubiquitin-conjugating enzyme E2 L3; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
Egr2E3 SUMO-protein ligase EGR2. (72 aa)
IkbkgNF-kappa-B essential modulator isoform X3. (410 aa)
Ddx58Probable ATP-dependent RNA helicase DDX58. (924 aa)
Scamp3Secretory carrier-associated membrane protein. (349 aa)
Ankra2Ankyrin repeat family A protein 2. (283 aa)
Rangap1Ran GTPase-activating protein 1. (556 aa)
Pias2E3 SUMO-protein ligase PIAS2 isoform X1. (613 aa)
Nek6Serine/threonine-protein kinase Nek6; Belongs to the protein kinase superfamily. (313 aa)
VcpTransitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family. (806 aa)
Ube2kUbiquitin-conjugating enzyme E2 K isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
LOC106001046Stress-70 protein, mitochondrial pseudogene. (567 aa)
Smad7Mothers against decapentaplegic homolog. (427 aa)
Bag4BAG family molecular chaperone regulator 4. (456 aa)
Ube2j1Ubiquitin-conjugating enzyme E2 J1 isoform X2. (159 aa)
Trim37E3 ubiquitin-protein ligase TRIM37. (883 aa)
Ambra1Activating molecule in BECN1-regulated autophagy protein 1. (1243 aa)
Rad18E3 ubiquitin-protein ligase RAD18 isoform X1. (502 aa)
Polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1970 aa)
SkiSki oncogene. (719 aa)
Ube2k-2Ubiquitin-conjugating enzyme E2 K isoform X2; Belongs to the ubiquitin-conjugating enzyme family. (131 aa)
MycMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (435 aa)
Slc22a18Solute carrier family 22 member 18. (277 aa)
PacrgParkin coregulated gene protein. (126 aa)
ENSDORP00000025450annotation not available (102 aa)
Prr5lProline-rich protein 5-like. (367 aa)
Sumo1Small ubiquitin-related modifier 1. (83 aa)
EgfrReceptor protein-tyrosine kinase. (1215 aa)
Nae1NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. (537 aa)
Sh3kbp1SH3 domain-containing kinase-binding protein 1 isoform X5. (707 aa)
Laptm4bLysosomal-associated transmembrane protein 4B. (228 aa)
ENSDORP00000024671annotation not available (72 aa)
Ube2j2Ubiquitin-conjugating enzyme E2 J2. (259 aa)
TubbTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
GlmnGlomulin. (595 aa)
Smad6Mothers against decapentaplegic homolog. (401 aa)
Mul1Mitochondrial ubiquitin ligase activator of NFKB 1. (352 aa)
ENSDORP00000024097annotation not available (150 aa)
Rtn2Reticulon. (465 aa)
Usp2Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (396 aa)
ENSDORP00000023736annotation not available (111 aa)
Myod1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (325 aa)
Trp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (356 aa)
CamlCalcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. (295 aa)
Arih1RBR-type E3 ubiquitin transferase. (409 aa)
Atp6v0cV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (112 aa)
Uchl1Ubiquitin carboxyl-terminal hydrolase. (223 aa)
Gsk3bGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
Smad3Mothers against decapentaplegic homolog. (425 aa)
ENSDORP00000023166annotation not available (120 aa)
RalaRas-related protein Ral-A. (206 aa)
CalrCalreticulin. (417 aa)
Fzd4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (538 aa)
Ubbpolyubiquitin-B. (155 aa)
Traf5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa)
LOC105986631Ubiquitin-like. (77 aa)
ENSDORP00000022369annotation not available (102 aa)
ENSDORP00000022365annotation not available (281 aa)
Gabarapl1Gamma-aminobutyric acid receptor-associated protein-like 1. (87 aa)
CrkAdapter molecule crk. (304 aa)
Prkar2bcAMP-dependent protein kinase type II-beta regulatory subunit. (258 aa)
Arrb2Beta-arrestin-2 isoform X1. (420 aa)
ENSDORP00000022159annotation not available (103 aa)
Uba52ubiquitin-60S ribosomal protein L40. (128 aa)
Yod1Ubiquitin thioesterase OTU1. (349 aa)
Rnf8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (81 aa)
Bcl10B-cell lymphoma/leukemia 10. (117 aa)
Patz1POZ-, AT hook-, and zinc finger-containing protein 1 isoform X5. (687 aa)
ENSDORP00000021689annotation not available (176 aa)
Psma3-2Proteasome subunit alpha type. (241 aa)
Per1Period circadian protein homolog 1 isoform X1. (827 aa)
Fbxw7F-box/WD repeat-containing protein 7 isoform X1. (708 aa)
Axin2Axin-2. (837 aa)
Mfhas1Malignant fibrous histiocytoma-amplified sequence 1. (1055 aa)
Ube2tUbiquitin-conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family. (205 aa)
SpartSpartin isoform X1. (671 aa)
Pax6Paired box protein Pax-6 isoform X2. (561 aa)
LOC105993014ubiquitin-40S ribosomal protein S27a pseudogene. (147 aa)
Eif4e2Eukaryotic translation initiation factor 4E type 2; Belongs to the eukaryotic initiation factor 4E family. (208 aa)
Tcp1T-complex protein 1. (402 aa)
AicdaSingle-stranded DNA cytosine deaminase. (55 aa)
ENSDORP00000020658annotation not available (108 aa)
Fam178bProtein FAM178B. (542 aa)
Mc4rMelanocortin receptor 4. (332 aa)
Trib2Tribbles homolog 2. (343 aa)
Ube2d1Ubiquitin-conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
Axin1Axin-1. (868 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
Erlin2Erlin-2. (339 aa)
ENSDORP00000020034annotation not available (195 aa)
LOC105992166poly(rC)-binding protein 2 pseudogene. (310 aa)
Ywhae14-3-3 protein epsilon; Belongs to the 14-3-3 family. (255 aa)
PrkacbcAMP-dependent protein kinase catalytic subunit beta isoform X2; Belongs to the protein kinase superfamily. (351 aa)
Brca1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (79 aa)
Arrb1Beta-arrestin-1 isoform X1. (411 aa)
ENSDORP00000019733annotation not available (100 aa)
Washc1WAS protein family homolog 1. (474 aa)
GabarapGamma-aminobutyric acid receptor-associated protein. (117 aa)
Ube2g1Ubiquitin-conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family. (143 aa)
Hspa1bHeat shock protein family A (Hsp70) member 1B. (635 aa)
Rb1Retinoblastoma-associated protein isoform X1. (926 aa)
Gabarapl2Gamma-aminobutyric acid receptor-associated protein-like 2. (117 aa)
CacybpCalcyclin-binding protein. (229 aa)
Becn1Beclin-1. (448 aa)
LOC105999841Heat shock 70 kDa protein 1B; Belongs to the heat shock protein 70 family. (641 aa)
Ubxn7UBX domain-containing protein 7. (489 aa)
ENSDORP00000018748annotation not available (67 aa)
Trib1Tribbles homolog 1. (141 aa)
Tnk2Activated CDC42 kinase 1. (976 aa)
Ccdc50Coiled-coil domain containing 50. (226 aa)
SncaipSynphilin-1 isoform X2. (919 aa)
TxnipThioredoxin-interacting protein. (392 aa)
Dlg3Disks large homolog 3 isoform X1; Belongs to the MAGUK family. (849 aa)
Laptm4aLysosomal-associated transmembrane protein 4A. (233 aa)
Cul4bcullin-4B; Belongs to the cullin family. (871 aa)
Rnf20E3 ubiquitin protein ligase; Belongs to the BRE1 family. (975 aa)
Tcp1-2T-complex protein 1 subunit alpha. (557 aa)
Dnm1lDynamin-1-like protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (727 aa)
Xrcc5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (692 aa)
Otub1Ubiquitin thioesterase. (271 aa)
Kdm4aLysine-specific demethylase 4A. (1012 aa)
Ywhaz14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (245 aa)
Ubash3bUbiquitin-associated and SH3 domain-containing protein B. (516 aa)
Hspd160 kDa heat shock protein, mitochondrial; Belongs to the chaperonin (HSP60) family. (573 aa)
Hsp90ab1Heat shock protein HSP 90-beta. (723 aa)
Smc6Structural maintenance of chromosomes protein 6 isoform X1. (1097 aa)
Flt3Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa)
TriobpTRIO and F-actin-binding protein. (593 aa)
Ripk1Receptor-interacting serine/threonine-protein kinase 1. (662 aa)
Smg5Protein SMG5 isoform X2. (1017 aa)
Nploc4Nuclear protein localization protein 4 homolog. (603 aa)
Usp25Ubiquitin carboxyl-terminal hydrolase 25; Belongs to the peptidase C19 family. (984 aa)
NlkSerine/threonine-protein kinase NLK. (428 aa)
CluClusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (446 aa)
Ptk2bProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
Cul4acullin-4A; Belongs to the cullin family. (594 aa)
Rnf40E3 ubiquitin protein ligase; Belongs to the BRE1 family. (961 aa)
GpiGlucose-6-phosphate isomerase; Belongs to the GPI family. (558 aa)
Pou5f1POU domain protein. (360 aa)
Anapc2Anaphase-promoting complex subunit 2; Belongs to the cullin family. (824 aa)
Ubxn1UBX domain-containing protein 1. (297 aa)
Rnf31E3 ubiquitin-protein ligase RNF31 isoform X1. (1070 aa)
RfflE3 ubiquitin-protein ligase rififylin isoform X1. (366 aa)
Jak1Tyrosine-protein kinase. (1155 aa)
Arrdc5Arrestin domain-containing protein 5. (322 aa)
Aup1Ancient ubiquitous protein 1 isoform X1. (421 aa)
Traf3TNF receptor-associated factor. (549 aa)
Tsg101Tumor susceptibility gene 101 protein. (380 aa)
DaxxDeath domain-associated protein 6 isoform X1. (745 aa)
Map1lc3bMicrotubule-associated proteins 1A/1B light chain 3B. (115 aa)
Isg15Ubiquitin-like protein ISG15. (159 aa)
PmlProtein PML isoform X1. (830 aa)
Chek2Serine/threonine-protein kinase Chk2. (467 aa)
Hspa9Stress-70 protein, mitochondrial; Belongs to the heat shock protein 70 family. (679 aa)
Herc2E3 ubiquitin-protein ligase HERC2. (4730 aa)
Faf2LOW QUALITY PROTEIN: FAS-associated factor 2. (392 aa)
AurkaAurora kinase A; Belongs to the protein kinase superfamily. (415 aa)
Wrap53Telomerase Cajal body protein 1. (539 aa)
Bag2BAG family molecular chaperone regulator 2. (196 aa)
Cul5Cullin-5; Belongs to the cullin family. (751 aa)
Arrdc1Arrestin domain-containing protein 1. (372 aa)
FanclE3 ubiquitin-protein ligase FANCL. (353 aa)
FhitBis(5'-adenosyl)-triphosphatase. (150 aa)
Usp19Ubiquitin carboxyl-terminal hydrolase 19. (1322 aa)
Snx9Sorting nexin-9. (565 aa)
Atxn3Ataxin-3 isoform X1. (355 aa)
Rnf34E3 ubiquitin-protein ligase RNF34. (383 aa)
Stub1E3 ubiquitin-protein ligase CHIP. (267 aa)
Zfp746Zinc finger protein 746. (636 aa)
Rps27aubiquitin-40S ribosomal protein S27a. (156 aa)
Rpl560S ribosomal protein L5. (302 aa)
Hsp90aa1Heat shock protein HSP 90-alpha. (733 aa)
Cul3Cullin-3 isoform X1; Belongs to the cullin family. (762 aa)
Fzd6Frizzled-6; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa)
Gpr37Prosaposin receptor GPR37. (605 aa)
Prkar2acAMP-dependent protein kinase type II-alpha regulatory subunit. (358 aa)
Slf1Ankyrin repeat domain-containing protein 32 isoform X1. (1055 aa)
Smad5Mothers against decapentaplegic homolog. (465 aa)
Slf2Protein FAM178A-like. (1028 aa)
NgfrTumor necrosis factor receptor superfamily member 16. (409 aa)
Rtn3Reticulon. (256 aa)
Hif1aHypoxia-inducible factor 1-alpha. (246 aa)
JkampJNK1/MAPK8-associated membrane protein isoform X1. (310 aa)
Prdx6Peroxiredoxin-6. (224 aa)
Traf2TNF receptor-associated factor. (484 aa)
Kcnq3Potassium voltage-gated channel subfamily KQT member 3; Belongs to the potassium channel family. (841 aa)
BidBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (193 aa)
ShprhE3 ubiquitin-protein ligase SHPRH isoform X1. (1678 aa)
Rpa2Replication protein A 32 kDa subunit isoform X1. (255 aa)
Rtn4Reticulon. (1108 aa)
Det1DET1 homolog. (550 aa)
Pdlim2PDZ and LIM domain protein 2. (128 aa)
Cul9Cullin-9; Belongs to the cullin family. (2272 aa)
Pias4E3 SUMO-protein ligase PIAS4. (517 aa)
Pias1E3 SUMO-protein ligase PIAS1. (647 aa)
Ube2bUbiquitin-conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
Asb4Ankyrin repeat and SOCS box protein 4. (426 aa)
Sipa1l1Signal-induced proliferation-associated 1-like protein 1. (1789 aa)
CbsCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (561 aa)
SykTyrosine-protein kinase. (633 aa)
Cul1Cullin-1; Belongs to the cullin family. (776 aa)
Kcnh2Potassium voltage-gated channel subfamily H member 2. (1141 aa)
LynTyrosine-protein kinase. (512 aa)
Cul2Cullin-2; Belongs to the cullin family. (645 aa)
Traf4TNF receptor-associated factor. (470 aa)
Erbb3Receptor tyrosine-protein kinase erbB-3. (1339 aa)
Pa2g4Proliferation-associated protein 2G4. (377 aa)
Tmbim6Bax inhibitor 1; Belongs to the BI1 family. (121 aa)
Rpl2360S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family. (140 aa)
Pcbp2poly(RC)-binding protein 2 isoform X2. (362 aa)
Ube2l6ubiquitin/ISG15-conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
SpopSpeckle-type POZ protein isoform X1. (374 aa)
Ndufs2NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial; Belongs to the complex I 49 kDa subunit family. (457 aa)
Bcl2Apoptosis regulator Bcl-2. (196 aa)
Ubcpolyubiquitin-C. (153 aa)
Trib3Tribbles homolog 3. (357 aa)
Psma3Proteasome 20S subunit alpha 3. (232 aa)
Fate1Fetal and adult testis expressed 1. (99 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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