STRINGSTRING
Dnaic1 Dnaic1 Grb2 Grb2 Pck2 Pck2 Rab13 Rab13 Tbc1d4 Tbc1d4 Trib3 Trib3 Foxo4 Foxo4 Gpt Gpt Csrp3 Csrp3 Inhbb Inhbb Pparg Pparg Shc1 Shc1 Slc25a33 Slc25a33 Vamp2 Vamp2 Srsf5 Srsf5 Lep Lep Mast3 Mast3 Eprs Eprs Prkdc Prkdc Dennd4c Dennd4c Pou4f2 Pou4f2 Rpe65 Rpe65 Igf1r Igf1r Ndel1 Ndel1 Xbp1 Xbp1 Parp1 Parp1 Fbp1 Fbp1 Sh2b2 Sh2b2 Akt1 Akt1 Soga1 Soga1 Ghrhr Ghrhr Lpin2 Lpin2 Capn10 Capn10 Cdk4 Cdk4 Slc27a1 Slc27a1 Pkm Pkm Syap1 Syap1 Appl1 Appl1 Enpp1 Enpp1 Rab12 Rab12 Pten Pten Cpeb1 Cpeb1 Rarres2 Rarres2 Zdhhc7 Zdhhc7 Ucp2 Ucp2 Srd5a1 Srd5a1 Lpin1 Lpin1 Slc2a4 Slc2a4 Pck1 Pck1 Trarg1 Trarg1 LOC106001479 LOC106001479 Fer Fer Pdpk1 Pdpk1 Slc9a1 Slc9a1 Irs1 Irs1 Irs4 Irs4 Phip Phip Cyfip1 Cyfip1 Adipoq Adipoq Wdtc1 Wdtc1 Slc29a2 Slc29a2 Ghsr Ghsr Tsc2 Tsc2 Eef2k Eef2k Pdk4 Pdk4 Cpeb2 Cpeb2 Prkcz Prkcz Stxbp4 Stxbp4 Grb10 Grb10 Foxo1 Foxo1 Rab31 Rab31 Inpp5k Inpp5k Otop1 Otop1 Hnrnpk Hnrnpk Slc27a4 Slc27a4 LOC105989938 LOC105989938 Sp1 Sp1 Apc Apc Pik3r3 Pik3r3 Potea Potea Eif4ebp1 Eif4ebp1 Pak1 Pak1 Pdk2 Pdk2 Igfbp1 Igfbp1 Gpld1 Gpld1 Got1 Got1 Sgk1 Sgk1 C2cd5 C2cd5 Rb1 Rb1 Grb14 Grb14 Sik2 Sik2 Aprt Aprt Rhoq Rhoq Pik3r1 Pik3r1 Hmgcs2 Hmgcs2 Gh Gh Kl Kl Pde3b Pde3b Gclc Gclc LOC105990085 LOC105990085 Igf2 Igf2 Gsk3a Gsk3a Pklr Pklr Errfi1 Errfi1 Usf1 Usf1 Ywhag Ywhag Eif4ebp2 Eif4ebp2 Socs7 Socs7 ENSDORP00000022906 ENSDORP00000022906 Prkci Prkci ENSDORP00000023169 ENSDORP00000023169 Insig2 Insig2 ENSDORP00000023223 ENSDORP00000023223 Gpam Gpam Gsk3b Gsk3b ENSDORP00000023481 ENSDORP00000023481 Rab10 Rab10 Slc2a8 Slc2a8 Srebf1 Srebf1 Rab15 Rab15 Ptpn2 Ptpn2 Insr Insr Lpin3 Lpin3 Insig1 Insig1 Ptpn1 Ptpn1 Sorbs1 Sorbs1 Ptpra Ptpra Bcar3 Bcar3 Znf106 Znf106 Myc Myc Smarcc1 Smarcc1 LOC105991166 LOC105991166 Gck Gck LOC105990733 LOC105990733 Akt2 Akt2 Bcar1 Bcar1 Cav2 Cav2 Akt3 Akt3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Dnaic1Dynein intermediate chain 1, axonemal. (700 aa)
Grb2Growth factor receptor-bound protein 2. (217 aa)
Pck2Phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform X1. (643 aa)
Rab13Ras-related protein Rab-13. (203 aa)
Tbc1d4TBC1 domain family member 4. (1285 aa)
Trib3Tribbles homolog 3. (357 aa)
Foxo4Forkhead box protein O4. (504 aa)
GptAlanine aminotransferase 1. (496 aa)
Csrp3Cysteine and glycine-rich protein 3 isoform X1. (193 aa)
InhbbInhibin beta B chain. (659 aa)
PpargPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (475 aa)
Shc1SHC-transforming protein 1 isoform X2. (473 aa)
Slc25a33Solute carrier family 25 member 33; Belongs to the mitochondrial carrier (TC 2.A.29) family. (321 aa)
Vamp2Vesicle-associated membrane protein 2 isoform X2. (118 aa)
Srsf5Serine/arginine-rich splicing factor 5 isoform X2. (269 aa)
LepLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
Mast3Microtubule associated serine/threonine kinase 3. (71 aa)
EprsBifunctional glutamate/proline--tRNA ligase. (1403 aa)
PrkdcDNA-dependent protein kinase catalytic subunit; Belongs to the PI3/PI4-kinase family. (4088 aa)
Dennd4cDENN domain-containing protein 4C. (1884 aa)
Pou4f2POU domain protein. (348 aa)
Rpe65Retinoid isomerohydrolase. (533 aa)
Igf1rTyrosine-protein kinase receptor. (923 aa)
Ndel1Nuclear distribution protein nudE-like 1 isoform X3. (345 aa)
Xbp1LOW QUALITY PROTEIN: X-box-binding protein 1. (275 aa)
Parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1000 aa)
Fbp1Fructose-1,6-bisphosphatase 1; Belongs to the FBPase class 1 family. (350 aa)
Sh2b2SH2B adapter protein 2. (436 aa)
Akt1Non-specific serine/threonine protein kinase. (188 aa)
Soga1Protein SOGA1. (1333 aa)
GhrhrGrowth hormone-releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (392 aa)
Lpin2Phosphatidate phosphatase LPIN2 isoform X2. (894 aa)
Capn10Calpain-10; Belongs to the peptidase C2 family. (501 aa)
Cdk4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
Slc27a1Long-chain fatty acid transport protein 1. (437 aa)
PkmPyruvate kinase; Belongs to the pyruvate kinase family. (531 aa)
Syap1Synapse-associated protein 1. (359 aa)
Appl1DCC-interacting protein 13-alpha. (634 aa)
Enpp1Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (908 aa)
Rab12Ras-related protein Rab-12. (227 aa)
PtenPhosphatase and tensin homolog. (396 aa)
Cpeb1Cytoplasmic polyadenylation element-binding protein 1 isoform X1. (562 aa)
Rarres2Retinoic acid receptor responder protein 2. (160 aa)
Zdhhc7Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (307 aa)
Ucp2Mitochondrial uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (309 aa)
Srd5a13-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). (255 aa)
Lpin1Phosphatidate phosphatase LPIN1 isoform X1. (927 aa)
Slc2a4Solute carrier family 2, facilitated glucose transporter member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
Pck1Phosphoenolpyruvate carboxykinase, cytosolic [GTP]. (622 aa)
Trarg1Tumor suppressor candidate 5. (182 aa)
LOC106001479Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (492 aa)
FerTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (775 aa)
Pdpk13-phosphoinositide-dependent protein kinase 1 isoform X1. (552 aa)
Slc9a1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (802 aa)
Irs1Insulin receptor substrate 1. (1239 aa)
Irs4Insulin receptor substrate 4. (1262 aa)
PhipPH-interacting protein isoform X1. (1758 aa)
Cyfip1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
AdipoqAdiponectin. (251 aa)
Wdtc1WD and tetratricopeptide repeats protein 1. (357 aa)
Slc29a2Equilibrative nucleoside transporter 2. (451 aa)
GhsrGrowth hormone secretagogue receptor type 1; Belongs to the G-protein coupled receptor 1 family. (366 aa)
Tsc2Tuberin isoform X1. (1809 aa)
Eef2kEukaryotic elongation factor 2 kinase. (723 aa)
Pdk4Protein-serine/threonine kinase. (412 aa)
Cpeb2Cytoplasmic polyadenylation element-binding protein 2 isoform X2. (482 aa)
PrkczProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (518 aa)
Stxbp4Syntaxin-binding protein 4 isoform X2. (515 aa)
Grb10Growth factor receptor-bound protein 10 isoform X2. (541 aa)
Foxo1Forkhead box protein O1. (537 aa)
Rab31Ras-related protein Rab-31. (189 aa)
Inpp5kInositol polyphosphate 5-phosphatase K. (405 aa)
Otop1Otopetrin-1. (461 aa)
HnrnpkHeterogeneous nuclear ribonucleoprotein K isoform X2. (466 aa)
Slc27a4Long-chain fatty acid transport protein 4. (643 aa)
LOC105989938Proprotein convertase subtilisin/kexin type 9-like; Belongs to the peptidase S8 family. (579 aa)
Sp1Transcription factor Sp1. (786 aa)
ApcAdenomatous polyposis coli protein isoform X2. (2842 aa)
Pik3r3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
PoteaPOTE ankyrin domain family member A. (116 aa)
Eif4ebp1Eukaryotic translation initiation factor 4E-binding protein 1. (118 aa)
Pak1Non-specific serine/threonine protein kinase. (544 aa)
Pdk2Protein-serine/threonine kinase. (427 aa)
Igfbp1Insulin-like growth factor-binding protein 1 isoform X1. (273 aa)
Gpld1Phosphatidylinositol-glycan-specific phospholipase D. (830 aa)
Got1Aspartate aminotransferase. (413 aa)
Sgk1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (445 aa)
C2cd5C2 domain-containing protein 5. (859 aa)
Rb1Retinoblastoma-associated protein isoform X1. (926 aa)
Grb14Growth factor receptor-bound protein 14. (507 aa)
Sik2Serine/threonine-protein kinase SIK2. (924 aa)
AprtAdenine phosphoribosyltransferase. (117 aa)
RhoqRho-related GTP-binding protein RhoQ. (205 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
Hmgcs23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
GhSomatotropin. (230 aa)
KlKlotho. (1020 aa)
Pde3bPhosphodiesterase. (1011 aa)
GclcGlutamate--cysteine ligase catalytic subunit. (489 aa)
LOC105990085Tyrosine-protein phosphatase non-receptor type. (333 aa)
Igf2Insulin-like growth factor II. (176 aa)
Gsk3aGlycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily. (483 aa)
PklrPyruvate kinase; Belongs to the pyruvate kinase family. (575 aa)
Errfi1ERBB receptor feedback inhibitor 1. (446 aa)
Usf1Upstream stimulatory factor 1 isoform X1. (310 aa)
Ywhag14-3-3 protein gamma; Belongs to the 14-3-3 family. (247 aa)
Eif4ebp2Eukaryotic translation initiation factor 4E-binding protein 2. (120 aa)
Socs7Suppressor of cytokine signaling 7. (580 aa)
ENSDORP00000022906annotation not available (71 aa)
PrkciProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (601 aa)
ENSDORP00000023169annotation not available (123 aa)
Insig2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa)
ENSDORP00000023223annotation not available (74 aa)
GpamGlycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa)
Gsk3bGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
ENSDORP00000023481annotation not available (114 aa)
Rab10Ras-related protein Rab-10. (200 aa)
Slc2a8Solute carrier family 2, facilitated glucose transporter member 8 isoform X2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (479 aa)
Srebf1Sterol regulatory element-binding protein 1 isoform X1. (1126 aa)
Rab15Ras-related protein Rab-15. (212 aa)
Ptpn2Tyrosine-protein phosphatase non-receptor type 2. (397 aa)
InsrTyrosine-protein kinase receptor. (1183 aa)
Lpin3Phosphatidate phosphatase LPIN3. (846 aa)
Insig1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (237 aa)
Ptpn1Tyrosine-protein phosphatase non-receptor type. (436 aa)
Sorbs1Sorbin and SH3 domain containing 1. (1290 aa)
PtpraReceptor-type tyrosine-protein phosphatase alpha. (789 aa)
Bcar3Breast cancer anti-estrogen resistance protein 3. (798 aa)
Znf106Zinc finger protein 106. (144 aa)
MycMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (435 aa)
Smarcc1SWI/SNF complex subunit SMARCC1. (1061 aa)
LOC105991166Histone H2A; Belongs to the histone H2A family. (102 aa)
GckPhosphotransferase. (466 aa)
LOC105990733Allergen Fel d 4-like; Belongs to the calycin superfamily. Lipocalin family. (177 aa)
Akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
Bcar1Breast cancer anti-estrogen resistance protein 1 isoform X1. (931 aa)
Cav2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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