STRINGSTRING
Smad2 Smad2 Eng Eng Smad7 Smad7 Tgfb3 Tgfb3 Smad6 Smad6 Lrg1 Lrg1 Tgfbr2 Tgfbr2 Fermt2 Fermt2 Tgfb1 Tgfb1 Snx25 Snx25 Fkbp1a Fkbp1a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Smad2Mothers against decapentaplegic homolog. (467 aa)
EngEndoglin isoform X2. (646 aa)
Smad7Mothers against decapentaplegic homolog. (427 aa)
Tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
Smad6Mothers against decapentaplegic homolog. (401 aa)
Lrg1Leucine-rich alpha-2-glycoprotein. (320 aa)
Tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa)
Fermt2Fermitin family homolog 2. (680 aa)
Tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (130 aa)
Snx25Sorting nexin-25. (767 aa)
Fkbp1aPeptidylprolyl isomerase. (108 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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