STRINGSTRING
Hoxa10 Hoxa10 Osr2 Osr2 Ift52 Ift52 Msx1 Msx1 Bmp4 Bmp4 Gja5 Gja5 Dync2h1 Dync2h1 Traf3ip1 Traf3ip1 Pbx2 Pbx2 Mycn Mycn Znf219 Znf219 Bmpr1a Bmpr1a Dlx5 Dlx5 Hoxd10 Hoxd10 Hoxd12 Hoxd12 Evx2 Evx2 Tbx5 Tbx5 Smad4 Smad4 Ihh Ihh Enpp1 Enpp1 Fras1 Fras1 Gli2 Gli2 Msx2 Msx2 Rnf165 Rnf165 Megf8 Megf8 Alx3 Alx3 Lef1 Lef1 Fgf10 Fgf10 Hnf1a Hnf1a Runx2 Runx2 Intu Intu Hand2 Hand2 Pcnt Pcnt Sema3c Sema3c Grhl2 Grhl2 Hoxc10 Hoxc10 Hoxc11 Hoxc11 Plxna2 Plxna2 Hoxa13 Hoxa13 Hoxa11 Hoxa11 Hoxa9 Hoxa9 Dicer1 Dicer1 Shox2 Shox2 Dkk1 Dkk1 Fzd6 Fzd6 Map3k20 Map3k20 Wnt9a Wnt9a Cyp26b1 Cyp26b1 Fbn2 Fbn2 Med1 Med1 Gnas Gnas Sall1 Sall1 Ift140 Ift140 Tgfb2 Tgfb2 Pcsk5 Pcsk5 Idua Idua Chd7 Chd7 Wdpcp Wdpcp Prrx1 Prrx1 Lrp6 Lrp6 Flvcr1 Flvcr1 Sall3 Sall3 Frem2 Frem2 Smarca4 Smarca4 Lrp4 Lrp4 Psen1 Psen1 Psen2 Psen2 Ift88 Ift88 Tbc1d32 Tbc1d32 Gli3 Gli3 Ptch1 Ptch1 B9d1 B9d1 Notch2 Notch2 Ift122 Ift122 ENSDORP00000000772 ENSDORP00000000772 Osr1 Osr1 Hdac1 Hdac1 Aldh1a2 Aldh1a2 Zbtb16 Zbtb16 Col2a1 Col2a1 Pbx1 Pbx1 Tfap2a Tfap2a Tmem231 Tmem231 Reck Reck Sall4 Sall4 Sulf1 Sulf1 Hdac2 Hdac2 Chst11 Chst11 Crabp2 Crabp2 Alx4 Alx4 Fbxw4 Fbxw4 Impad1 Impad1 Bax Bax Gdf5 Gdf5 Lnpk Lnpk Gpc3 Gpc3 Tmem107 Tmem107 Rarg Rarg Bcl2l11 Bcl2l11 Ece1 Ece1 Col3a1 Col3a1 Fgfr2 Fgfr2 Wnt3 Wnt3 Fuz Fuz En1 En1 Lrp5 Lrp5 Tp63 Tp63 ENSDORP00000017990 ENSDORP00000017990 Sp8 Sp8 Atrx Atrx Ttbk2 Ttbk2 Sox4 Sox4 Cacna1c Cacna1c Rarb Rarb Mks1 Mks1 ENSDORP00000020585 ENSDORP00000020585 Tbx2 Tbx2 Tbx4 Tbx4 ENSDORP00000021345 ENSDORP00000021345 Rab23 Rab23 Tulp3 Tulp3 Tfap2b Tfap2b Pitx2 Pitx2 Ror2 Ror2 Wnt5a Wnt5a Tbx3 Tbx3 Wdr19 Wdr19 Pkdcc Pkdcc ENSDORP00000022774 ENSDORP00000022774 Mecom Mecom Nipbl Nipbl Fgfr1 Fgfr1 Bak1 Bak1 Asph Asph Fgf8 Fgf8 Sik3 Sik3 Sp9 Sp9 Zic3 Zic3 Rpgrip1l Rpgrip1l Ski Ski Sfrp2 Sfrp2 Grem1 Grem1 Nog Nog Mbnl1 Mbnl1 Rdh10 Rdh10 Lmbr1 Lmbr1 Fgf4 Fgf4 Rspo2 Rspo2 Gna12 Gna12 C2cd3 C2cd3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Hoxa10Homeobox protein Hox-A10 isoform X2. (94 aa)
Osr2Protein odd-skipped-related 2 isoform X1. (312 aa)
Ift52Intraflagellar transport protein 52 homolog isoform X2. (425 aa)
Msx1Homeobox protein MSX-1. (196 aa)
Bmp4Bone morphogenetic protein 4. (409 aa)
Gja5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (310 aa)
Dync2h1Cytoplasmic dynein 2 heavy chain 1. (4270 aa)
Traf3ip1TRAF3-interacting protein 1 isoform X4. (601 aa)
Pbx2pre-B-cell leukemia transcription factor 2. (430 aa)
MycnN-myc proto-oncogene protein. (461 aa)
Znf219Zinc finger protein 219. (725 aa)
Bmpr1aReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
Dlx5Homeobox protein DLX-5 isoform X1. (289 aa)
Hoxd10Homeobox protein Hox-D10. (340 aa)
Hoxd12Homeobox protein Hox-D12. (269 aa)
Evx2Homeobox even-skipped homolog protein 2. (479 aa)
Tbx5T-box transcription factor TBX5. (518 aa)
Smad4Mothers against decapentaplegic homolog. (528 aa)
IhhIndian hedgehog protein. (397 aa)
Enpp1Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (908 aa)
Fras1Extracellular matrix protein FRAS1. (3950 aa)
Gli2Zinc finger protein GLI2. (1549 aa)
Msx2Homeobox protein MSX-2. (169 aa)
Rnf165RING finger protein 165. (347 aa)
Megf8Multiple epidermal growth factor-like domains protein 8 isoform X2. (2789 aa)
Alx3Homeobox protein aristaless-like 3. (344 aa)
Lef1Lymphoid enhancer-binding factor 1. (370 aa)
Fgf10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (223 aa)
Hnf1aHepatocyte nuclear factor 1-alpha. (631 aa)
Runx2Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (570 aa)
IntuProtein inturned. (853 aa)
Hand2Heart- and neural crest derivatives-expressed protein 2. (217 aa)
PcntPericentrin. (2788 aa)
Sema3csemaphorin-3C; Belongs to the semaphorin family. (752 aa)
Grhl2Grainyhead-like protein 2 homolog. (631 aa)
Hoxc10Homeobox protein Hox-C10. (343 aa)
Hoxc11Homeobox protein Hox-C11. (304 aa)
Plxna2plexin-A2. (1891 aa)
Hoxa13Homeobox protein Hox-A13. (217 aa)
Hoxa11Homeobox protein Hox-A11 isoform X3. (300 aa)
Hoxa9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (272 aa)
Dicer1Endoribonuclease Dicer isoform X1; Belongs to the helicase family. Dicer subfamily. (1912 aa)
Shox2Short stature homeobox protein 2 isoform X2. (190 aa)
Dkk1Dickkopf-related protein 1. (268 aa)
Fzd6Frizzled-6; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa)
Map3k20Mitogen-activated protein kinase kinase kinase MLT isoform X2. (455 aa)
Wnt9aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
Cyp26b1Cytochrome P450 26B1 isoform X1; Belongs to the cytochrome P450 family. (512 aa)
Fbn2Fibrillin-2. (2821 aa)
Med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1546 aa)
GnasGuanine nucleotide-binding protein G(S) subunit alpha isoform X1. (394 aa)
Sall1Sal-like protein 1. (144 aa)
Ift140Intraflagellar transport protein 140 homolog. (1494 aa)
Tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (443 aa)
Pcsk5Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (912 aa)
Iduaalpha-L-iduronidase. (592 aa)
Chd7chromodomain-helicase-DNA-binding protein 7 isoform X1. (2995 aa)
WdpcpWD repeat-containing and planar cell polarity effector protein fritz homolog. (718 aa)
Prrx1Paired mesoderm homeobox protein 1. (132 aa)
Lrp6Low-density lipoprotein receptor-related protein 6. (1602 aa)
Flvcr1Feline leukemia virus subgroup C receptor-related protein 1. (484 aa)
Sall3Sal-like protein 3. (1076 aa)
Frem2FRAS1-related extracellular matrix protein 2. (3167 aa)
Smarca4Transcription activator BRG1. (1513 aa)
Lrp4Low-density lipoprotein receptor-related protein 4. (1882 aa)
Psen1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
Psen2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (447 aa)
Ift88Intraflagellar transport protein 88 homolog isoform X1. (825 aa)
Tbc1d32Protein broad-minded. (1299 aa)
Gli3Transcriptional activator GLI3. (1508 aa)
Ptch1Protein patched homolog 1. (1300 aa)
B9d1B9 domain-containing protein 1. (166 aa)
Notch2Neurogenic locus notch homolog protein 2. (2322 aa)
Ift122Intraflagellar transport protein 122 homolog isoform X2. (1242 aa)
ENSDORP00000000772annotation not available (687 aa)
Osr1Protein odd-skipped-related 1. (266 aa)
Hdac1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (477 aa)
Aldh1a2Retinal dehydrogenase 2; Belongs to the aldehyde dehydrogenase family. (474 aa)
Zbtb16Zinc finger and BTB domain-containing protein 16 isoform X1. (673 aa)
Col2a1Collagen alpha-1(II) chain isoform X2. (1487 aa)
Pbx1pre-B-cell leukemia transcription factor 1 isoform X1. (430 aa)
Tfap2aTranscription factor AP-2-alpha isoform X1. (437 aa)
Tmem231Transmembrane protein 231. (263 aa)
ReckReversion-inducing cysteine-rich protein with Kazal motifs. (971 aa)
Sall4Sal-like protein 4. (998 aa)
Sulf1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (870 aa)
Hdac2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa)
Chst11Carbohydrate sulfotransferase. (352 aa)
Crabp2Cellular retinoic acid-binding protein 2 isoform X1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (138 aa)
Alx4Homeobox protein aristaless-like 4. (411 aa)
Fbxw4F-box/WD repeat-containing protein 4. (406 aa)
Impad1Inositol monophosphatase 3. (358 aa)
BaxApoptosis regulator BAX. (143 aa)
Gdf5Growth/differentiation factor 5. (496 aa)
LnpkLOW QUALITY PROTEIN: protein lunapark. (415 aa)
Gpc3Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (431 aa)
Tmem107Transmembrane protein 107. (147 aa)
RargRetinoic acid receptor gamma isoform X1. (458 aa)
Bcl2l11Bcl-2-like protein 11 isoform X1. (200 aa)
Ece1Endothelin-converting enzyme 1. (724 aa)
Col3a1Collagen alpha-1(III) chain. (1437 aa)
Fgfr2Fibroblast growth factor receptor. (819 aa)
Wnt3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
FuzProtein fuzzy homolog isoform X2. (415 aa)
En1Homeobox protein engrailed-like. (140 aa)
Lrp5Low-density lipoprotein receptor-related protein 5. (1616 aa)
Tp63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
ENSDORP00000017990annotation not available (198 aa)
Sp8Transcription factor Sp8. (468 aa)
AtrxTranscriptional regulator ATRX isoform X1. (2472 aa)
Ttbk2Tau-tubulin kinase 2. (436 aa)
Sox4Transcription factor SOX. (249 aa)
Cacna1cVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1179 aa)
RarbRetinoic acid receptor beta isoform X1. (448 aa)
Mks1Meckel syndrome type 1 protein. (559 aa)
ENSDORP00000020585annotation not available (80 aa)
Tbx2T-box transcription factor TBX2. (590 aa)
Tbx4T-box transcription factor TBX4 isoform X2. (551 aa)
ENSDORP00000021345annotation not available (171 aa)
Rab23Ras-related protein Rab-23. (236 aa)
Tulp3Tubby-like protein; Belongs to the TUB family. (452 aa)
Tfap2bTranscription factor AP-2-beta isoform X2. (460 aa)
Pitx2Homeobox protein. (325 aa)
Ror2Tyrosine-protein kinase transmembrane receptor ROR2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (933 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
Tbx3T-box transcription factor TBX3. (133 aa)
Wdr19WD repeat-containing protein 19. (1266 aa)
PkdccExtracellular tyrosine-protein kinase PKDCC. (456 aa)
ENSDORP00000022774annotation not available (389 aa)
MecomMDS1 and EVI1 complex locus protein EVI1 isoform X2. (1047 aa)
NipblNipped-B protein. (2804 aa)
Fgfr1Fibroblast growth factor receptor. (822 aa)
Bak1Bcl-2 homologous antagonist/killer. (211 aa)
AsphAspartyl/asparaginyl beta-hydroxylase. (169 aa)
Fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (233 aa)
Sik3Serine/threonine-protein kinase SIK3 isoform X1. (1311 aa)
Sp9LOW QUALITY PROTEIN: transcription factor Sp9. (273 aa)
Zic3Zinc finger protein ZIC 3 isoform X1. (466 aa)
Rpgrip1lProtein fantom. (1283 aa)
SkiSki oncogene. (719 aa)
Sfrp2Secreted frizzled-related protein 2. (296 aa)
Grem1Gremlin. (184 aa)
NogNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (233 aa)
Mbnl1Muscleblind-like protein 1 isoform X1. (387 aa)
Rdh10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
Lmbr1Limb region 1 protein homolog; Belongs to the LIMR family. (432 aa)
Fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (52 aa)
Rspo2R-spondin-2. (243 aa)
Gna12Guanine nucleotide-binding protein subunit alpha-12. (305 aa)
C2cd3C2 domain-containing protein 3. (2245 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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