STRINGSTRING
Rab4a Rab4a LOC105994343 LOC105994343 Shank3 Shank3 Gsk3b Gsk3b ENSDORP00000023261 ENSDORP00000023261 Grin1 Grin1 Rapsn Rapsn Necab2 Necab2 Gria1 Gria1 Dnm3 Dnm3 Pick1 Pick1 Gria2 Gria2 Syndig1 Syndig1 Flot1 Flot1 Gnas Gnas Homer3 Homer3 Slc9a3r1 Slc9a3r1 Ptpn5 Ptpn5 Pten Pten Homer1 Homer1 Ophn1 Ophn1 Flot2 Flot2 Cacng2 Cacng2 Cacng4 Cacng4 Neto2 Neto2 Grin2a Grin2a Map1a Map1a Homer2 Homer2 Shank2 Shank2 Plcg1 Plcg1 Myo5b Myo5b Dlg4 Dlg4 Nsf Nsf Cacng3 Cacng3 Drd2 Drd2 Dlg3 Dlg3 Snx27 Snx27 Fus Fus Grip2 Grip2 Sqstm1 Sqstm1 LOC105983195 LOC105983195 Arpc2 Arpc2 Shisa6 Shisa6 Shank1 Shank1 LOC105989882 LOC105989882 Camk2a Camk2a Prnp Prnp Nedd4 Nedd4 LOC106002162 LOC106002162 Akap5 Akap5 Cacng8 Cacng8 Igsf11 Igsf11 ENSDORP00000020585 ENSDORP00000020585 Cdk5r1 Cdk5r1 Canx Canx Il1r1 Il1r1 LOC105997620 LOC105997620 Shisa7 Shisa7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Rab4aRas-related protein Rab-4A isoform X1. (218 aa)
LOC105994343Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (224 aa)
Shank3SH3 and multiple ankyrin repeat domains protein 3. (1417 aa)
Gsk3bGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
ENSDORP00000023261annotation not available (66 aa)
Grin1LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 1. (926 aa)
Rapsn43 kDa receptor-associated protein of the synapse isoform X1. (412 aa)
Necab2N-terminal EF-hand calcium-binding protein 2. (319 aa)
Gria1Glutamate receptor 1 isoform X2. (906 aa)
Dnm3Dynamin-3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (845 aa)
Pick1PRKCA-binding protein. (394 aa)
Gria2Glutamate receptor 2. (842 aa)
Syndig1Synapse differentiation-inducing gene protein 1. (258 aa)
Flot1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (241 aa)
GnasGuanine nucleotide-binding protein G(S) subunit alpha isoform X1. (394 aa)
Homer3Homer protein homolog 3. (101 aa)
Slc9a3r1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (359 aa)
Ptpn5Tyrosine-protein phosphatase non-receptor type 5 isoform X1. (369 aa)
PtenPhosphatase and tensin homolog. (396 aa)
Homer1Homer protein homolog 1. (361 aa)
Ophn1Oligophrenin-1. (782 aa)
Flot2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
Cacng2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (295 aa)
Cacng4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa)
Neto2Neuropilin and tolloid-like protein 2. (518 aa)
Grin2aGlutamate receptor ionotropic, NMDA 2A. (1301 aa)
Map1aMicrotubule-associated protein 1A. (2699 aa)
Homer2Homer protein homolog 2 isoform X2. (355 aa)
Shank2SH3 and multiple ankyrin repeat domains protein 2 isoform X1. (1832 aa)
Plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
Myo5bUnconventional myosin-Vb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1845 aa)
Dlg4Disks large homolog 4; Belongs to the MAGUK family. (657 aa)
NsfVesicle-fusing ATPase. (744 aa)
Cacng3Voltage-dependent calcium channel gamma-3 subunit. (315 aa)
Drd2D(2) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (443 aa)
Dlg3Disks large homolog 3 isoform X1; Belongs to the MAGUK family. (849 aa)
Snx27LOW QUALITY PROTEIN: sorting nexin-27. (380 aa)
FusRNA-binding protein FUS isoform X2. (516 aa)
Grip2Glutamate receptor-interacting protein 2. (1042 aa)
Sqstm1Sequestosome-1. (433 aa)
LOC105983195UPF0183 protein C16orf70 homolog. (423 aa)
Arpc2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (209 aa)
Shisa6Protein shisa-6 homolog. (455 aa)
Shank1SH3 and multiple ankyrin repeat domains protein 1. (1300 aa)
LOC105989882Actin-related protein 2/3 complex subunit 2 pseudogene. (295 aa)
Camk2aCalcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (488 aa)
PrnpMajor prion protein; Belongs to the prion family. (262 aa)
Nedd4E3 ubiquitin-protein ligase. (859 aa)
LOC106002162Disks large homolog 4-like. (150 aa)
Akap5A-kinase anchor protein 5. (438 aa)
Cacng8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (415 aa)
Igsf11Immunoglobulin superfamily member 11. (427 aa)
ENSDORP00000020585annotation not available (80 aa)
Cdk5r1Cyclin-dependent kinase 5 activator. (310 aa)
CanxCalnexin. (560 aa)
Il1r1Interleukin-1 receptor type 1 isoform X1. (574 aa)
LOC105997620Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (282 aa)
Shisa7Protein shisa-7. (380 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.